- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04760223
Reducing Stigma Towards Depression Among Adolescents
Reducing Depression-related Stigma and Increasing Treatment-seeking Among Adolescents: Randomized Controlled Trial of a Brief Video Intervention
Study Overview
Detailed Description
Young people present with the higher prevalence of mental health disorders compared to individuals at any other age, with up to 20% of adolescents likely to experience mental health disorders. Around 50% of mental health conditions start before the age of 14 and the onset of 75% of cases is before the age of 18. Depression is the most common diagnosis and epidemiological studies suggest that at any one time 8% to 10% of adolescents have severe depression. This means that the major burden of assessing and managing adolescent depression falls on primary care practitioners. Depression is a principal cause of illness and disability in teenagers, and suicide is the third most common cause of death among older adolescents. Mental health problems can significantly affect the development of children and young people having an enduring impact on their health and social functioning in adulthood. However, 75% of adolescents with mental health problems are not in contact with mental health services,8 and the primary reason for the reluctance to seek help is stigma.
Stigma refers to negative beliefs and stereotypes held toward a specific group of people and adversely affects people with mental illness. Public stigma refers to negative attitudes and beliefs that motivate individuals to fear, reject, avoid, and discriminate against people with mental illness. Individuals with mental illness expect to face prejudice and discrimination (anticipated stigma) and internalize public stereotypes of people with mental illness (self-stigma). Adolescents are particularly aware of how others perceive them and care greatly about what their peers think of them. Public stigma toward youngsters with mental illness has been identified as a barrier to seeking help; therefore, reducing public stigma among young people at risk for or even experiencing depression could enhance their receptivity to seeking help or treatment.
Applying strategies to reduce stigma towards mental health care among adolescents with high levels of depression may prevent worsening of symptoms, ameliorate impaired functioning, and reduce risks for long-term psychiatric illness. Among possible strategies, studies19 have shown that social contact is the most effective type of intervention to reduce stigmatizing attitudes. Social contact involves interpersonal contact with members of the stigmatized group: members of the general public who meet and interact with individuals who suffer from depression are likely to lessen their stigma. Corrigan identified the most important ingredients of contact-based programs: an empowered presenter with lived experience who attains his/her goals (e.g., "I was able to fight the depression and go back to school"). Although direct, in-person social contact, as well as indirect, video-based social contact have effectively improved attitudes toward mental issues and care, the latter can be implemented on a larger scale, use minimal resources and be easily disseminated.
The purpose of this study is to: (1) examine adolescents' stigma-related attitudes towards depression; and (2) test the utility of a brief video-based intervention in reducing stigma towards depression and increasing help-seeking intentions.
The investigators propose to randomly assign 1,000 individuals aged 14-18 in to either: (a) brief video-based intervention 1 ('Video 1'); (b) brief video-based intervention 2 ('Video 2'); or (c) no intervention video control arm ('Control'). The intervention videos will focus on empowered presenters with depression. The presenters will be 16-year-old adolescent professional actors, one of them is a boy (Video 1), one is a girl (Video 2). They each will share his/her personal story regarding depression and describe how social support from family, friends, and professionals have helped them overcome their symptoms and recover. The third group will watch a same length video with unrelated contents. Assessments will occur at baseline and at post-intervention and will tap into demographic identifiers and attitudes around stigma and help-seeking questionnaires.
Actors will be hired through the Child Study Center, and / or through the Standardized Patient Program of Teaching and Learning Center, Yale School of Medicine. Actors will be compensated and follow standardized patient best practices, including those specifically pertaining to under-age actors.
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Contacts and Locations
Study Locations
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Connecticut
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New Haven, Connecticut, United States, 06520
- Yale University
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New York
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New York, New York, United States, 10032
- New York State Psychiatric Institute
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- 14-18-year-old
- US residents
- English speaker
Exclusion Criteria:
- None
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Health Services Research
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Video intervention 1
We presented a 100-second video to study participants to reduce stigma towards depression (a boy presenter).
The protagonist discussed his own depression and how getting help assist him.
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a 100-second video, presenting a personal story of a boy/girl dealing with depression
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|
Experimental: Video intervention 2
We presented a 100-second video to study participants to reduce stigma towards depression (a girl presenter).
The protagonist discussed his own depression and how getting help assist her.
|
a 100-second video, presenting a personal story of a boy/girl dealing with depression
|
|
Placebo Comparator: control video 1
A 100-second video presenting a boy without depression
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a 100-second video, presenting a personal story of a boy/girl dealing with depression
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Placebo Comparator: control video 2
A 100-second video presenting a girl without depression
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a 100-second video, presenting a personal story of a boy/girl dealing with depression
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Stigma levels
Time Frame: Through the study completion (pre and post-intervention), an average of one month
|
Level of stigma towards depression measured by the 9-item Depression Stigma Scale (DSS).
This is a 9-item self report questionnaire to measure the personal stigma towards depression.
It has 5-point Likert scale tanging from strongly disagree (1) and strongly agree (5).
It had test-retest reliability of 0.71 and internal consistency of 0.76 (Griffiths KM et al. 2004)
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Through the study completion (pre and post-intervention), an average of one month
|
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help-seeking intentions
Time Frame: Through the study completion (pre and post-intervention), an average of one month
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The General Help-Seeking Questionnaire (GHSQ) has been developed to measure help-seeking intentions from different sources (friend, parent, mental health professional, and others) and is divided into personal-emotional problems and suicidal thoughts.
The instrument consists of 10 items repeated twice for each part, measured with a 7-point Likert scale ranging from 1 (extremely unlikely) to 7 (extremely likely).
One question is stated as "I would not seek help from anyone" and is reverse scored.
Higher scores on this scale indicate more help-seeking.
The GHSQ has shown good psychometric properties: Cronbach's alpha = 0.70, and test-retest of 0.86 for personal-emotional problems, and Cronbach's alpha = 0.83, and test-retest of 0.88 for suicidal thoughts (Wilson CJ et al. 2008)
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Through the study completion (pre and post-intervention), an average of one month
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Collaborators and Investigators
Investigators
- Study Director: Doron Amsalem, MD, Columbia University and NYSPI
Publications and helpful links
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- ResearchFMH
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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