Epidemiology of Digital Nerve Injuries in the Stockholm County

This is a registry and medical record based epidemiological description of patients with digitial nerve injuies in the Stockholm County, Sweden

Study Overview

• Status: Completed
• Conditions: Digital Nerve Injury
• Intervention / Treatment: Procedure: Suture of digital nerve

Detailed Description

The primary aim of this study was to describe the epidemiology of patients with surgically repaired digital nerve injuries in a Swedish population during the period 2012 to 2018. Secondary aims included a description of the patient population, surgical treatment and rehabilitation regimens following digital nerve injury. Comparisons were made between groups consisting in patients with isolated nerve injuries and those with a concomitant flexor tendon injury.

METHODS

Patients In this cohort study, all patients treated with surgical repair of a digital nerve injury at the Department of Hand Surgery at Södersjukhuset, Stockholm, Sweden were included. Inclusion period was between 2012-01-01 and 2018-12-31. Patients were identified through the Swedish national quality registry for Hand surgery (HAKIR). Inclusion criteria were the diagnostic codes (ICD-10) for a digital nerve injury in the thumb (S64.3) or finger (S64.4) in combination with the surgical code (KKÅ97) Nomesco classification of surgical procedures for nerve repair (ACB29). A total of 1,329 patients were identified. Exclusion criteria were concomitant skeletal injury, amputations, severe soft tissue injuries, or if the injury needed microvascular reconstruction. Patients reciding outside the Stockholm region and children below 18 years of age were also excluded. A total of 1,004 patients were included for the final analysis. The study population was thereafter divided into two groups: patients with an isolated digital nerve injury and patients with a ditial nerve injry with a concomitant tendon injury. All clinical data was collected through search of medical records.

• Study Type: Observational
• Enrollment (Actual): 1004

Contacts and Locations

Study Locations

• Sweden
  • Stockholm, Sweden, 11883
    • Karolinska Institutet Södersjukhuset, Department of clinical research and education

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

All patients treated with surgical repair of a operatively for a digital nerve injury at the Department of Hand Surgery at Södersjukhuset, Stockholm, Sweden between 2012-01-01 and 2018-12-31 were included.

Description

Inclusion Criteria:

• diagnostic codes (ICD-10) for a digital nerve injury in the thumb (S64.3) or finger (S64.4) in combination with the surgical code (KKÅ97) Nomesco classification of surgical procedures for nerve repair (ACB29).

Exclusion Criteria:

• concomitant skeletal injury
• amputations
• severe soft tissue injuries
• injury needed microvascular reconstruction.
• Patients reciding outside the Stockholm region and
• patient age below 18 years of age

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Digital nerve injury, surgical treatment, isolated injury; Patient over the age of 18 with an isolated injury to a digital nerve.	Procedure: Suture of digital nerve; The digital nerves were sutured according to the discretion of the treating surgeon and the standard procedure was three epineural sutures 8.0 or 9.0 nylon under loop magnification. Concomitant tendon injuries were also sutured according to the discretion of the treating surgeon, most commonly with two loop sutures (four strand core) and a peritendinous PDS suture.
Digital nerve injury, surgical treatment, concomittant flexor tendon injury; Patient over the age of 18 with an injury to a digital nerve and a concomittant flexor tendon injury.	Procedure: Suture of digital nerve; The digital nerves were sutured according to the discretion of the treating surgeon and the standard procedure was three epineural sutures 8.0 or 9.0 nylon under loop magnification. Concomitant tendon injuries were also sutured according to the discretion of the treating surgeon, most commonly with two loop sutures (four strand core) and a peritendinous PDS suture.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Incidence	The incidence of digital nerve injury as calculated as the numbers of treated patients divided by the population at risk	at study inclusion

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Demographic features of the patient cohort	date of birth, gender, injured hand, time and date of injury and surgery. Injured nerve, injury level, injury mechanism and type of injury, total or partial nerve injury, isolated nerve injury/concomitant flexor tendon injury, and postoperative complications. Smoking status, profession, numbres of visits to health care professionals.	at study inclusion
Health care interventions	time from injury to surgery, time from injury to rehabilitation, types of rehabilitation, number of visits to health care personnel, days of sick leave	through study completion, at an average 6 months

Collaborators and Investigators

• Sponsor: Karolinska Institutet
• Collaborators: Region Stockholm
• Investigators: Principal Investigator: Marianne Arner, Professor, Karolinska Institutet

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2021
• Primary Completion (Actual): June 1, 2021
• Study Completion (Actual): June 1, 2021

Study Registration Dates

• First Submitted: October 7, 2021
• First Submitted That Met QC Criteria: February 25, 2022
• First Posted (Actual): March 8, 2022

Study Record Updates

• Last Update Posted (Actual): March 8, 2022
• Last Update Submitted That Met QC Criteria: February 25, 2022
• Last Verified: February 1, 2022

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Wounds and Injuries
• Other Study ID Numbers: Digital nerve injury, epi

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No