Impact of Night Shift Work on 24-hour Blood Glucose Levels

Impact of Regular Night Shift Work on 24-hour Blood Glucose Levels in Nurses

This study will determine whether nurses regularly working night shifts have elevated 24-hour glucose levels compared to nurses regularly working day shifts, using continuous glucose monitoring (CGM).

Study Overview

• Status: Completed
• Conditions: Metabolic Disease; Circadian Rhythm; Inversion

• Study Type: Observational
• Enrollment (Actual): 22

Contacts and Locations

Study Locations

• United States
  • Washington
    • Spokane, Washington, United States, 99204
      • Providence Sacred Heart Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 14 years to 61 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Full time nurses working either day shifts or night shifts

Description

Inclusion Criteria:

• • RNs working at least a 0.6 FTE and 12-hour night or day shift (not able to alternate between days and nights) for at least the past two months

  • Free from presence of uncontrolled chronic illness and specifically prediabetes, Type 1 or Type 2 diabetes (but not including history of gestational diabetes) and not currently taking any glucose-lowering or steroid medication
  • Not currently pregnant or breastfeeding
  • English speaking and able to provide informed consent
  • Must own and know how to operate a Smartphone
  • Must be willing and able to wear two small sensors attached by adhesive for the study duration, the Fibion SENS activity monitor and the Dexcom G6 continuous glucose monitor
  • Must regularly consume food during shifts and refrain from actively attempting weight loss during the study duration
  • Must work only one job at the time of study participation

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Prospective

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
Day Shift; Nurses regularly working 12hr day shifts
Night Shift; Nurses regularly working night shift

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
24hr glucose	continuous glucose monitoring	7 days

Collaborators and Investigators

• Sponsor: Lincoln Memorial University
• Collaborators: Providence St Joseph Health
• Investigators: Principal Investigator: Lindsey Miller, Lincoln Memorial University

Study record dates

Study Major Dates

• Study Start (Actual): November 8, 2022
• Primary Completion (Actual): July 30, 2023
• Study Completion (Actual): July 30, 2023

Study Registration Dates

• First Submitted: September 26, 2022
• First Submitted That Met QC Criteria: September 26, 2022
• First Posted (Actual): September 29, 2022

Study Record Updates

• Last Update Posted (Actual): March 25, 2025
• Last Update Submitted That Met QC Criteria: March 6, 2025
• Last Verified: March 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Metabolic Diseases
• Other Study ID Numbers: STUDY2022000529

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No