The State of Nebulizer Therapy in Russian Federation (SoNeT)

The State of Nebulizer Therapy in Russian Federation: a National Survey Among Medicine Physicians

It is known that the inhalation (nebulizer) use of drugs is of great importance in the intensive care of patients with acute and chronic respiratory failure of various origins.

Searching PubMed data for the last 5 years (2017-2022) for the keywords "nebulizer therapy" revealed 533 publications, and "mesh nebulizer therapy" - only 25 sources.

During the same period, the national database (E-Library) has 75 publications for the keywords "nebulizer therapy", and 4 sources for "mesh nebulizer therapy".

It should be noted that almost all publications are devoted to the use of nebulizers for specific diseases and pathological syndromes. There are no works evaluating the adherence of specialists, systemic indications and actually used methods.

The aim of trial is to study the current state of the use of nebulizer therapy in medical organizations and identify ways to improve its effectiveness This study is planned to be carried out using a questionnaire using a database based on the Internet electronic survey form.

Study Overview

• Status: Active, not recruiting
• Conditions: Respiratory Failure; Respiratory Disease; Survey
• Intervention / Treatment: Other: Survey

Detailed Description

We intend to involve at least 3 medical organizations in the subjects of the Russian Federation with a population of up to 1 million people; at least 5 medical organizations in the constituent entities of the Russian Federation with a population level of 1 to 3 million people, at least 7 organizations with a population level of more than 3 million people. In cities of the Russian Federation with a population of 1 million people or more - at least 5 medical organizations, and in the cities of Moscow and St. Petersburg - at least 10 medical organizations.

• Study Type: Observational
• Enrollment (Estimated): 370

Contacts and Locations

Study Locations

• Russian Federation
  • Krasnoyarsk, Russian Federation
    • Alexey Gritsan

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Medicine physicians (VMP) practicing in the hospital and in the community settings.

Description

Inclusion Criteria:

• Medical physicians

Exclusion Criteria:

• Lack of experience in conducting nebulizer therapy. Lack of technical capability for nebulizer therapy in a medical organization.

Study Plan

How is the study designed?

Design Details

• Observational Models: Other
• Time Perspectives: Prospective

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Medicine physicians; Anesthesiologists, intensive care specialists, heads of departments of anesthesiology and intensive care, deputy chief physicians for anesthesiology and intensive care (heads of centers), employees of the department of anesthesiology and intensive care, pulmonologists working in medical organizations that use nebulizer therapy.	Other: Survey; an electronic survey will be conducted

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Structure of indications, methods and frequency of use of nebulizer therapy	Registration of the structure and indications for nebulizer therapy	up to 1 month after inclusion

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Drugs and frequency of their use during nebulizer therapy	Registration of drugs used for nebulizer therapy	up to 6 month after inclusion
The frequency of use of nebulizer therapy for high-flow oxygen therapy, non-invasive ventilation and mechanical ventilation	Frequency of use of nebulizer therapy for various types of respiratory support	up to 6 month after inclusion

Collaborators and Investigators

• Sponsor: Russian Federation of Anesthesiologists and Reanimatologists
• Investigators: Principal Investigator: Alexey Gritsan, MD, Krasnoyarsk State Medical University n.a. prof. V.F. Voyno-Yasenetsky

Study record dates

Study Major Dates

• Study Start (Actual): July 1, 2023
• Primary Completion (Actual): June 30, 2024
• Study Completion (Estimated): July 31, 2025

Study Registration Dates

• First Submitted: November 7, 2022
• First Submitted That Met QC Criteria: November 14, 2022
• First Posted (Actual): November 15, 2022

Study Record Updates

• Last Update Posted (Actual): April 4, 2025
• Last Update Submitted That Met QC Criteria: April 1, 2025
• Last Verified: April 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Respiratory Insufficiency; Respiratory Tract Diseases; Respiration Disorders
• Other Study ID Numbers: FARCT0004

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No