Dental Autotransplantation or Immediate Single Implant for the Replacement of a Hopeless Molar.

Dental Autotransplantation or Immediate Single Implant for the Replacement of a Hopeless Molar: a Comparative Case Series Study.

The aim of this comparative study is to know the differences between the soft tissue volume changes around the autotransplanted tooth and the dental implant placed immediately after the extraction of a posterior tooth. Patient-centered results will also be obtained after having received one or the other treatment.

Study Overview

• Status: Completed
• Conditions: Surgery, Oral; Transplantation, Autologous; Autografts
• Intervention / Treatment: Procedure: Tooth Autotransplantation; Procedure: Immediate implant

Detailed Description

Dental autotransplantation has high levels of success in permanent teeth with open apex. The results of success in permanent teeth with closed apex are somewhat lower but sufficient to consider the treatment as a viable alternative and to extend the therapeutic range of the treatment to older ages.

The aim of this prospective observational investigation is to evaluate the dimensional and attachment changes that occur in the treated areas and in the autotransplanted teeth respectively of adult patients with permanent teeth with closed apex. All adult patients receiving a dental autotransplantation between the years 2022 and 2023 will be included.

Pre-treatment, volume and insertion parameters will be recorded before and one year after treatment. The comparison with the extraction and dental implant treatment will be made using the digital records that are usually obtained during the performance of this treatment. The comparison will be made with the same number of patients who have been recruited for the dental autotransplant treatment, and the volumetric changes that occur will also be analyzed.

The volume comparisons will be carried out using the Medit Link digital measurement software (Medit, Seoul, Republic of Korea) and data will be obtained and analyzed statistically in order to draw the appropriate conclusions.

• Study Type: Observational
• Enrollment (Actual): 29

Contacts and Locations

Study Locations

• Spain
  • Alicante, Spain, 03001
    • Clínica Dental Esteve

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 80 years (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

Patients who come to the clinic and need a tooth extracted.

Description

Inclusion Criteria:

• Patients in ASA-I health status
• Aged between 18 and 80 years,
• Present a tooth in need of extraction with a mature candidate donor tooth compatible with the recipient bed
• Acceptance of proposed treatment of dental autotransplantation

Exclusion Criteria:

• Unavailability of a candidate donor tooth
• Refusal of proposed treatment of dental autotransplantation

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Only
• Time Perspectives: Prospective

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Autotransplantation; Patients who receive one tooth autotransplanted.	Procedure: Tooth Autotransplantation; Place another tooth in the place of the newly extracted tooth in the same patient.; Other Names: Dental autotransplant
Immediate implant; Patients who receive one inmediate dental implant.	Procedure: Immediate implant; Place a dental implant immediately after tooth extraction.; Other Names: Type 1 implant

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Soft tissue volume changes	Soft tissue volume changes in the buccal side of the site in mm3	2 times measurement: day 0 and 6 months after
Periodontal probing pocket depth	Periodontal probing pocket depth in mm	6 months after

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Patients satisfaction after treatment	Satisfaction assessed by Numeric Rating Scale (NRS) form 0 to 10, being 0 "not satisfied at all" and 10 "very satisfied".	6 months after the reception of the treatment

Collaborators and Investigators

• Sponsor: Aula Dental Avanzada
• Investigators: Principal Investigator: Guillem Esteve-Pardo, PhD, Clínica Dental Esteve

Study record dates

Study Major Dates

• Study Start (Actual): May 1, 2021
• Primary Completion (Actual): September 1, 2023
• Study Completion (Actual): September 2, 2023

Study Registration Dates

• First Submitted: December 8, 2022
• First Submitted That Met QC Criteria: December 27, 2022
• First Posted (Actual): December 30, 2022

Study Record Updates

• Last Update Posted (Actual): April 26, 2024
• Last Update Submitted That Met QC Criteria: April 25, 2024
• Last Verified: April 1, 2024

More Information

Terms related to this study

• Other Study ID Numbers: PROSP AUTO

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED
• IPD Plan Description: Data will be shared upon reasonable request.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No