Investigating Proximal Muscle Strength Effects by Incorporating Proximal Muscle Lengthening

The purpose of this study is to assess strength gains of proximal musculature in the nondominant upper extremity after implementing blood flow restriction (BFR) and myofascial release (MFR) with the supplementation of whey protein.

Study Overview

• Status: Active, not recruiting
• Conditions: Proximal Muscle Strength; Proximal Muscle Lengthening
• Intervention / Treatment: Other: myofascial release; Device: blood flow restriction; Other: myofascial release

Detailed Description

The purpose of this study is to assess strength gains of proximal musculature in the nondominant upper extremity after implementing blood flow restriction (BFR) and myofascial release (MFR) with the supplementation of whey protein. Blood flow restricted (BFR) exercise is the brief and non-continuous blockage of venous blood flow using a device that restricts the flow of blood while exercising. This technique is used to produce hypertrophy (muscle growth) and strength responses while exercising at a lighter load than traditionally required to produce a similar response. Myofascial release (MFR) is a technique that involves applying gentle sustained pressure into the myofascial connective tissue restrictions to eliminate pain and restore motion.

• Study Type: Interventional
• Enrollment (Estimated): 60
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: LaToya L Green, EdD; Phone Number: 901-448-5888; Email: lgreen24@uthsc.edu
• Study Contact Backup: Name: Myra M Meekins, PhD; Phone Number: 901-448-5888; Email: mmeekins@uthsc.edu

Study Locations

• United States
  • Tennessee
    • Memphis, Tennessee, United States, 38163
      • University of Tennessee Health Science Center
      • Contact: Kimberly Williams, MS; Phone Number: 901-448-1343; Email: kwilli72@uthsc.edu
      • Contact: Jessica McMorris, MS; Phone Number: 901.448.5920; Email: jmcmorr1@uthsc.edu
      • Principal Investigator: LaToya L Green, EdD
      • Sub-Investigator: Myra M Meekins, PhD

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 30 years (Adult)
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Healthy individuals between the age of 18 and 30

Exclusion Criteria:

• Individuals with uncontrolled high blood pressure
• Individuals with sickle cell anemia, current pregnancy
• Individuals with a history of deep vein thrombosis
• Individuals with diabetes
• Individuals with active infection
• Individuals with less than normal range of motion or muscle strength
• Individuals with moderate to severe upper extremity injury in the past 12 months
• Individuals with a current diagnosis of cancer.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Myofascial Release; The Experimental group will receive a myofascial release pectoralis minor release intervention.	Other: myofascial release; Myofascial release (MFR) is a technique that involves applying gentle sustained pressure into the myofascial connective tissue restrictions to eliminate pain and restore motion.; Device: blood flow restriction; Blood flow restricted (BFR) exercise is the brief and non-continuous blockage of venous blood flow using a device that restricts the flow of blood while exercising. This technique is used to produce hypertrophy (muscle growth) and strength responses while exercising at a lighter load than traditionally required to produce a similar response.; Other: myofascial release; Sham MFR.
Sham Comparator: Sham Myofascial Release; The Control group will receive a sham myofascial release pectoralis minor release intervention.	Other: myofascial release; Myofascial release (MFR) is a technique that involves applying gentle sustained pressure into the myofascial connective tissue restrictions to eliminate pain and restore motion.; Device: blood flow restriction; Blood flow restricted (BFR) exercise is the brief and non-continuous blockage of venous blood flow using a device that restricts the flow of blood while exercising. This technique is used to produce hypertrophy (muscle growth) and strength responses while exercising at a lighter load than traditionally required to produce a similar response.; Other: myofascial release; Sham MFR.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Scapular retraction strength	Assess scapular retraction strength with a dynamometer	8 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
One repetition maximum (1RM)	maximum amount of weight that can be lifted one time for scapular retractors on a row machine	8 weeks

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Length for the pectoralis minor	Assess length of the pectoralis minor with a tape measure	8 weeks

Collaborators and Investigators

• Sponsor: University of Tennessee

Study record dates

Study Major Dates

• Study Start (Actual): October 16, 2023
• Primary Completion (Estimated): September 1, 2024
• Study Completion (Estimated): September 1, 2024

Study Registration Dates

• First Submitted: January 12, 2023
• First Submitted That Met QC Criteria: January 24, 2023
• First Posted (Actual): February 2, 2023

Study Record Updates

• Last Update Posted (Actual): March 20, 2024
• Last Update Submitted That Met QC Criteria: March 19, 2024
• Last Verified: March 1, 2024

More Information

Terms related to this study

• Keywords: blood flow restriction; myofascial release
• Other Study ID Numbers: 22-08926-XP

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: Yes