- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05981820
High Intensity Interval Training, Creatine Intake and Anaerobic Power
Effect of High Intensity Interval Training and Creatine Intake on Anaerobic Power and Muscle Strength
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Despite the time-efficiency of HIIT in inducing chronic physiological adaptation, it depleted phosphocreatine stores in the muscle and decrease power output. It has been observed that high-intensity exercise performance increases with the increase of intramuscular phosphocreatine. It is thought that with creatine supplementation, the rate of phosphocreatine resynthesis and mitochondrial transfer of ATP to the cytoplasm may increase. This suggests that performing HIIT with creatine supplementation will provide further improvement. Therefore, the purpose of this study to compare the effectiveness of HIIT with creatine supplement compared to HIIT only. We hypothesized that creatine supplementation intake with wingate-based HIIT will positively affect power capacity and performance-related parameters.
The research will be carried out using experimental research design, one of the quantitative research methods, to measure the variables and determine the relationship between dependent and independent variables. Anaerobic power, heart rate variability, leg strength, and body composition measurements of the participants will be made 1 week before the training program started and the week after the training program ended.
The G*power software was utilized in order to determine the appropriate sample size. It has been reported that a minimum of 12 participants, 6 in each group, should be included in the study (alpha value = 0.05, 1-beta value = 0.80, and effect size = 1.6). Measurement of tests and the Wingate-based HIIT program will be conducted in the Performance Laboratory of the Faculty of Sports Sciences of Ankara University. Twenty physically active adult men aged 18-30 years, who had no history of medical and did not use drugs or ergogenic aids, will be recruited voluntarily. The ethics committee approval for the study methodology was obtained from the Ethics Committee of Ankara University Rectorate (Number: E-56786525-050.04.04/378028 Decision Number: 2022/02) and it will be carried out in compliance with the Declaration of Helsinki's principles. Written inform consents which explain the study to the participant and any right and risk will be obtained prior to data collection. Permission for the research to be carried out in the Performance Laboratory of the Faculty of Sport Sciences of Ankara University will be obtained from the Deanery of the Faculty of Sport Sciences of Ankara University. Participants will be divided into two groups as those who will perform Wingate-based HIIT with creatine (C-HIIT) (age: 21,78 ± 1,79 years; height: 179.56 ± 8.26 cm; weight: 76.86 ± 10.66 kg) and those who will perform only Wingate-based HIIT (HIIT) (age: 20.167 ± 0,98 years; height: 172.33 ± 9,88 cm ; weight: 66.53 ± 9.51kg ). Out of twenty potential participants, only 15 participants agreed to participate in the study (HIIT=6, C-HIIT=9) and 5 dropped out because of sport injuries that occured before the study process.
IBM SPSS 24.0 program (SPSS Inc., Chicago, IL, USA) will be used to statistically analyze the data obtained in the study. First of all, the distribution of the data will be evaluated to determine the test used to compare the data as parametric or non-parametric. This normality distribution assessment will be tested with Shapiro Wilk, as both groups had less than 50 participants. Determination of the mean difference in within-group statistics will be performed with Paired Sample t-Test in data with normal distribution and with Wilcoxon test in data where it is not normal. Groups will be expressed as mean ± standard error. American Psychological Association (APA) 6.0 style will be used to report statistical differences. The alpha value will be accepted as 0.05 in all statistical analysis.
This study aimed to determine whether there was a difference in the effects of taking creatine supplementation with Wingate-based HIIT on anaerobic power, leg strength, heart rate variability and body composition.
The limitation of the current research is that the study will be carried out with a single gender. In future studies on the subject, the number of participants can be increased, female participants can be included in the research and it can be examined whether there is a difference between genders and to increase the generalizability of the study, the effects of different HIIT methods on anaerobic power, leg strength, heart rate variability and body composition can be compared by investigating. In addition, the trial period may be extended as longer periods are needed to see clearer changes in HRV.
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Contacts and Locations
Study Locations
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Ankara
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Golbasi, Ankara, Turkey, 06830
- Ankara University Spor Bilimleri Fakultesi
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Description
Inclusion Criteria:
- having no health and communication problem
- using no drugs or ergogenic aids
- being physically active adult men aged 18-30 years
Exclusion Criteria:
- using any drugs or ergogenic aids
- having any musculoskeletal problem
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: HIIT group
This group will only participate Wingate-based HIIT training. In the first three weeks:
In the last three weeks:
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In the first three weeks: Warm-up: Warm-up at 70 rpm for 4 minutes, including 2-3 seconds of maximal sprint at 1.30 and 2.30 minutes Wingate-based HIIT: HIIT 4 sets of 12x15 seconds of maximal repetitions with 15 seconds of passive rest between reps in each set Cool-down: 4 minutes of passive rest between sets In the last three weeks: Warm-up: Warm-up at 70 rpm for 4 minutes, including 2-3 seconds of maximal sprint at 1.30 and 2.30 minutes Wingate-based HIIT: HIIT 5 sets of 20x15 seconds of maximal repetitions with 15 seconds of passive rest between reps in each set Cool-down: 4 minutes of passive rest between sets |
Experimental: HIIT + creatine group
The HIIT + creatine group will participate the same Wingate-based HIIT training in addition to consume 10 g of creatine supplementation.
Participants in this group will use 10 g of creatine monohydrate by dissolved in 200 ml of water.
Creatine supplementation will be taken in two doses of five grams, 30 minutes before and after training.
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In the first three weeks: Warm-up: Warm-up at 70 rpm for 4 minutes, including 2-3 seconds of maximal sprint at 1.30 and 2.30 minutes Wingate-based HIIT: HIIT 4 sets of 12x15 seconds of maximal repetitions with 15 seconds of passive rest between reps in each set Cool-down: 4 minutes of passive rest between sets In the last three weeks: Warm-up: Warm-up at 70 rpm for 4 minutes, including 2-3 seconds of maximal sprint at 1.30 and 2.30 minutes Wingate-based HIIT: HIIT 5 sets of 20x15 seconds of maximal repetitions with 15 seconds of passive rest between reps in each set Cool-down: 4 minutes of passive rest between sets
To observe the effects of creatine in the study, 10 g of creatine supplementation was taken only on training days during the study period.
Participants used 10 g of creatine monohydrate by dissolved in 200 ml of water.
Creatine supplementation was taken in two doses of five grams, 30 minutes before and after training.
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Wingate anaerobic power test
Time Frame: two months
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The Wingate anaerobic power test will be performed using a bicycle ergometer.First, a four-minute warm-up protocol with a bicycle ergometer at 60-80 rpm pedal speed and 50 W workload will be applied.
Weights of 7.5% kilograms of their body weight for each participant will be placed on the pan of the bicycle ergometer and anaerobic power testing will be initiated.
When they reach the pedal speed to 150 rpm, the test will start.
Their maximal effort during 30-seconds will be collected.
The Wingate software will be used in which the program set up with the ergometers.
Information about the relevant power parameters during the test will be transmitted to the software program on the computer.
All power parameters such as both absolute and relative peak power, minimum power, average power etc. will be calculated by the software program automatically.
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two months
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Leg strength
Time Frame: two months
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Back and leg dynamometer (Takei-Back & Lift, Japan) will be used to measure leg strength.
Participants will be placed their feet on the dynamometer stand.
The legs will be bent at 15 angles, the body slightly forward, and the back straight.
The participants will pull the dynamometer bar, which they grasped with their hands, using only their legs, without changing their current position, until the knees will be extended.
Participants will repeat this trial twice, and the best value for each participant will be recorded.
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two months
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Collaborators and Investigators
Sponsor
Investigators
- Study Director: Dicle Aras, Ankara University Faculty of Sport Sciences
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- AnkaraUSport
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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