- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06276309
Protein Molecular Characteristics and Prognosis of Cervical Neuroendocrine Tumors
Study Overview
Status
Detailed Description
1. The clinical diagnosis and treatment data of 300 cases of cervical neuroendocrine tumors were used for prognostic analysis.
(1) The diagnosis and treatment information of cervical neuroendocrine carcinoma in multiple hospitals was collected, including clinical and medical data such as age, preoperative HPV genotyping, preoperative biopsy pathological results, postoperative histopathological results, FIGO staging, prognosis and survival information, and follow-up of patients.
2. Protein and other omics analysis was performed on paraffin tissues of 100 cases of cervical neuroendocrine tumors Paraffin samples collected from 100 cases of cervical neuroendocrine tumors were identified, processed and segmtioned, and protein concentration and proteome were determined to establish the molecular characteristics and prognostic targets of cervical neuroendocrine tumors.
Study Type
Enrollment (Estimated)
Contacts and Locations
Study Contact
- Name: Binhua Dong
- Phone Number: +86-0591-87558732
- Email: dongbinhua86@fjmu.edu.cn
Study Contact Backup
- Name: Pengming Sun
- Email: fmsun1975@fjmu.edu.cn
Study Locations
-
-
Fujian
-
Fuzhou, Fujian, China, 350001
- Recruiting
- Fujian Maternity and Child Health Hospital
-
Contact:
- Binhua Dong
- Phone Number: +8687558732
- Email: dbh18-jy@126.com
-
Fuzhou, Fujian, China
- Recruiting
- Fujian Provincial Hospital
-
Contact:
- Dongjie Chen
-
Ningde, Fujian, China
- Recruiting
- Ningde Mindong Hospital
-
Contact:
- Fang Xie
-
Putian, Fujian, China
- Recruiting
- Putian City first Hospital
-
Contact:
- Yi Chen
-
Quanzhou, Fujian, China
- Recruiting
- The Second Affiliated Hospital of Fujian Medical University
-
Contact:
- Luhong Li
-
Zhangzhou, Fujian, China, 363000
- Recruiting
- Zhangzhou Affiliated Hospital of Fujian Medical University
-
Contact:
- Feifeng Shi, M.D
-
-
Hubei
-
Wuhan, Hubei, China
- Recruiting
- Maternal and Child Health Hospital of Hubei Province
-
Contact:
- Hongning Cai, M.D
- Phone Number: +8615926224867
-
-
Hunan
-
Changsha, Hunan, China
- Recruiting
- Xiangya Hospital, Central South University
-
Contact:
- Yu Zhang
-
-
Jiangxi
-
Nanchang, Jiangxi, China
- Recruiting
- Jiangxi Maternal and Child Health Hospital
-
Contact:
- Ling Li
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
- Patients diagnosed with cervical neuroendocrine carcinoma by histopathology
- Clinical data were complete
Exclusion Criteria:
- Patients who are not being treated in our hospital
- Patients with lack of follow-up data, unable to obtain survival information
- Patients call to refuse to participate in this project
- The quality of paraffin specimens can not meet the requirements of proteome concentration determination
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
mortality rate
Time Frame: Among patients with cervical neuroendocrine carcinoma, the mortality rate within 3 years following surgery
|
3-year mortality rate for cervical neuroendocrine carcinoma
|
Among patients with cervical neuroendocrine carcinoma, the mortality rate within 3 years following surgery
|
Disease-free survival
Time Frame: Among patients with cervical neuroendocrine carcinoma, the disease-free survival within 3 years following surgery
|
3-year disease-free survival for cervical neuroendocrine carcinoma
|
Among patients with cervical neuroendocrine carcinoma, the disease-free survival within 3 years following surgery
|
Collaborators and Investigators
Investigators
- Study Chair: Pengming Sun, PhD, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- NECC2401
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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