Evaluation of the Modified VISTA Technique Using ALB-PRF vs CTG in the Treatment of Multiple Miller Class III Recessions

March 19, 2026 updated by: Tamani Mahmoud Abdullah Fakhri, Cairo University

Clinical Evaluation of the Modified VISTA Technique (M-VISTA )Using Albumin-platelet Rich Fibrin (Alb-PRF) Versus Connective Tissue Graft (CTG)in the Treatment of Multiple Miler Class III RT2 Recessions A Randomized Clinical Trial

treatment of miller class III RT2 gingival recession using modified vista technique using connective tissue graft vs albumin PRF

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

treatment of gingival recession is an important element in the treatment of periodontitis this study covers clinical evaluation of using the modified VISTA technique with using Albumin-PRF VS connective tissue graft in the treatment of miller class III / RT2 for root coverage outcomes

Study Type

Interventional

Enrollment (Estimated)

26

Phase

  • Phase 2
  • Phase 3

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Egypt
      • Cairo, Egypt, 4240101
        • Recruiting
        • Faculty of Dentistry Cairo University
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • 18 years old good oral hygiene

Exclusion Criteria:

  • smokers patients with poor oral hygiene

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: patients with gingival recession control group
patients with gingival recessions of miller class III /RT2 the control group will be treated with modified vista technique using connective tissue graft
Other: Connective tissue graft
regenerative properties
Experimental: patients with gingival recession interventional group
patients with gingival recessions of miller class III /RT2 the interventional group will be treated with modified vista technique using albumin PRF
Biological: ALB-PRF
regenerative properties

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
mean root coverage
Time Frame: 6 months
primary outcome measures of mean root coverage in millimeters by UNC15 periodontal probe
6 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
the percentage of mean root coverage
Time Frame: 6 months
secondary outcome measures in percentage by UNC15 probe
6 months
the percentage of complete root coverage
Time Frame: 6 months
measures in percentage by using UNC periodontal probe
6 months
recession depth
Time Frame: 6 months
measures in millimeters by using UNC15 periodontal probe
6 months
recession width
Time Frame: 6 months
measures in millimeters by using UNC 15periodontal probe
6 months
keratinized tissue width
Time Frame: 6 months
measures in millimeters by using UNC15 periodontal probe
6 months
clinical attachment level
Time Frame: 6 months
measures by millimeters by using UNC 15 periodontal probe
6 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Cairo University

Investigators

  • Study Director: Enji EA Ahmed, BDS.MDS.PHD, Cairo University
  • Study Director: Sarah SE Elbanna, BDS.MDS.PHD, Cairo University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 20, 2025

Primary Completion (Estimated)

December 20, 2026

Study Completion (Estimated)

January 30, 2027

Study Registration Dates

First Submitted

October 10, 2024

First Submitted That Met QC Criteria

October 13, 2024

First Posted (Actual)

October 16, 2024

Study Record Updates

Last Update Posted (Actual)

March 20, 2026

Last Update Submitted That Met QC Criteria

March 19, 2026

Last Verified

March 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • PER 3 -3 -1

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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