Investigation of the Relationship Between Executive Functions and Occupational Performance of Children With Duchenne Muscular Dystrophy

February 20, 2026 updated by: Başak Çağla Arslan, Lokman Hekim University
The effects of Duchenne muscular dystrophy and its treatments on executive functions and occupational performance are under-mentioned in the literature. The researches believe that developmental and cognitive research is needed to identify interventions for children with DMD to identify and adapt to both individual and social environments, including self-care, productivity and leisure activities. Therefore, the aim of this study was to examine executive functions and occupational performance in children with DMD and compare them with healthy controls.

Study Overview

Status

Enrolling by invitation

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

38

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
    • Çankaya
      • Ankara, Çankaya, Turkey (Türkiye), 06510
        • Lokman Hekim University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

All boys diagnosed with DMD between the ages of 6-12 years constitute the population of this study.

Description

Inclusion Criteria:

  • Being diagnosed with DMD
  • Volunteering to participate in the study by their parents and reading and signing the informed consent form

Exclusion Criteria:

  • Having a neuromuscular disease other than DMD and/or another diagnosed neuromuscular disease accompanying DMD
  • The family and/or the child has problems with cooperation in completing the assessments for any reason
  • Difficulty understanding and speaking the Turkish language

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Children with Duchenne muscular dystrophy
Other: Evaluations
Evaluations of executive functions and occupational performance
Healthy control group of children
Other: Evaluations
Evaluations of executive functions and occupational performance

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Demographic information form
Time Frame: one-time evaluation
one-time evaluation
Brooke upper extremity functional scale
Time Frame: one-time evaluation
It will be used to assess the functional level of the upper limbs of children with DMD. The classification consists of six stages and progression from the first to the sixth stage indicates a decrease in the functionality of the upper limb.
one-time evaluation
Vignos lower extremity functional scale
Time Frame: one-time evaluation
It will be used to assess the functional level of the lower limbs of children with DMD. The classification consists of ten stages and progression from the first to the tenth stage indicates a decrease in the functionality of the upper limb.
one-time evaluation
The Childhood Executive Functioning Inventory
Time Frame: one-time evaluation
This 26-item scale consists of 4 subscales: working memory (9 items), planning (6 items), inhibition (6 items) and regulation (5 items). Working memory and planning sub-dimensions constitute the total score of "working memory" and inhibition and regulation sub-dimensions constitute the total score of "inhibition". As the score obtained from the scale increases, the child's executive functions weaken.
one-time evaluation
Canadian Occupational Performance Measure
Time Frame: one-time evaluation
It will be used to assess children's occupational performance.
one-time evaluation

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Lokman Hekim University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 1, 2025

Primary Completion (Actual)

December 31, 2025

Study Completion (Estimated)

December 31, 2026

Study Registration Dates

First Submitted

May 10, 2024

First Submitted That Met QC Criteria

March 9, 2025

First Posted (Actual)

March 11, 2025

Study Record Updates

Last Update Posted (Actual)

February 23, 2026

Last Update Submitted That Met QC Criteria

February 20, 2026

Last Verified

February 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2023025

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

IPD Plan Description

Patient data in this study will not be shared with other researchers. The results of the study will be shared after anonymizing the demographic information of DMD and healthy children.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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