Surgeon-Guided Serratus Block in Breast Reduction Surgery

Postoperative Analgesic Efficacy of Intraoperative Surgeon-Guided Serratus Block: A Prospective Randomized Study

Surgeon guided serratus block, which can be performed by the surgeon in participants undergoing breast reduction surgery, may reduce the sensation of pain from the surgical field in the postoperative period. Thus, participants experience less pain in the postoperative period, consume less analgesics, and there is a decrease in related complications. The aim of this study was to evaluate the effects of the intraoperative surgeon guided serratus block applied on the analgesic consumption of the participants in the first 24 hours after surgery in participants undergoing breast reduction surgery.

Study Overview

• Status: Completed
• Conditions: Postoperative Pain Control; Breast Reduction
• Intervention / Treatment: Other: surgeon guided serratus block

• Study Type: Interventional
• Enrollment (Actual): 60
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey (Türkiye)
  • Samsun, Turkey (Türkiye), 55020
    • Samsun Training and Research Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Patient's willingness to be included in the study
• 18-65 years
• Woman
• Operated with inferior pedicled breast reduction technique
• The distance from the sternal notch to the nipple complex is between 25-40cm
• ASA I-II
• Breast Usg result BIRADS 1-2
• Patients who have not previously received RT to the breast and have no history of malignancy

Exclusion Criteria:

• Patient's request/refusal not to be included in the study
• Previous history of malignancy
• RT story,
• ASA 3-4-5-patient group
• Severe organ failure
• Alcohol, drug addiction
• Bupivacaine allergy
• Diagnosis of psychiatric illness and psychiatric drug use
• Surgery lasting longer than 3 hours
• Bleeding diathesis

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
No Intervention: Group Control; No intervention will be made in this group.
Experimental: Group SSPB; Surgeon guided serratus block will be applied before closing dermoglandular flaps	Other: surgeon guided serratus block; Surgeon guided Serratus Block will be applied before closing dermoglandular flaps

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
24 hours postoperatively opioid consumption	In the postoperative period, patients will be given opioids according to their pain density with a patient-controlled device, and the daily Morphine consumption in Patient Controlled Analgesia device will be collected and compared between groups.	24 hours

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
post-operative acute pain status, post-operative nausea-vomiting status, post-operative NRS determination of pain at rest and in motion determination of complications such as nausea, vomiting, itching, determination of the first PCA analgesic request.	Changes in the Numerical Rating Scale (NRS) will be recorded at rest and during movement. The participant's baseline NRS will be recorded, followed by measurements before and after neuraxial positioning and up to 24 hours post-surgery. The NRS is a unidimensional measure of pain intensity in adults. The 11-point numerical scale ranges from '0' representing one end of the pain spectrum (e.g. 'no pain') to '10' representing the other end (e.g. 'worst imaginable pain').	24 hours

Collaborators and Investigators

• Sponsor: alperen can kokten
• Investigators: Study Director: Ayhan Sönmez, Samsun University

Study record dates

Study Major Dates

• Study Start (Actual): December 1, 2024
• Primary Completion (Actual): October 30, 2025
• Study Completion (Actual): October 31, 2025

Study Registration Dates

• First Submitted: February 10, 2025
• First Submitted That Met QC Criteria: March 25, 2025
• First Posted (Actual): April 1, 2025

Study Record Updates

• Last Update Posted (Actual): January 29, 2026
• Last Update Submitted That Met QC Criteria: January 28, 2026
• Last Verified: January 1, 2026

More Information

Terms related to this study

• Keywords: breast reduction; postoperative pain control
• Additional Relevant MeSH Terms: Pain; Neurologic Manifestations; Postoperative Complications; Pathologic Processes; Pain, Postoperative
• Other Study ID Numbers: SGSB-01; SamsunU (Other Identifier: Samsun university)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No