A Study of Evacetrapib in Participants With Abnormal Cholesterol

Inclusion Criteria:

• Generally healthy participants or have stable medical conditions that, in the investigator's opinion, will not significantly alter the disposition of the drug, will not place the participant at increased risk by participating in the study, and will not interfere with interpretation of the data and meets one of the following criteria:

  • Elevated low-density lipoprotein cholesterol (LDL-C) greater than 100 milligrams per deciliter (mg/dL), OR
  • Low high-density lipoprotein cholesterol (HDL-C) less than 45 mg/dL (men); less than 50 mg/dL (women), OR
  • Hypercholesterolemia on stable statin therapy for at least 3 month
• Have a body mass index (BMI) of 18 to 37 kilograms per square meter (kg/m^2), inclusive, at screening

Exclusion Criteria:

• Have known allergies or intolerance to evacetrapib, related compounds
• Have history of recurrent rashes or chronic skin conditions
• Have significant history of or current chronic, active inflammatory conditions
• Have history or current evidence of significant neurological disorder
• Have long-standing diabetes that is insulin requiring
• Have history of or current symptoms of malabsorption syndromes, history of gastric bypass surgery