Ta strona została przetłumaczona automatycznie i dokładność tłumaczenia nie jest gwarantowana. Proszę odnieść się do angielska wersja za tekst źródłowy.

Targeted eHealth Intervention to Reduce Fear of Recurrence Among Breast Cancer Survivors (FoRtitude)

27 kwietnia 2018 zaktualizowane przez: Wake Forest University Health Sciences

Targeted eHealth Intervention to Reduce Fear of Recurrence Among Breast Cancer Survivors: The FoRtitude Trial

The FoRtitude trial aims to evaluate an eHealth intervention designed to teach breast cancer survivors strategies to manage anxiety about cancer recurrence. The eHealth intervention includes educational content and interactive tools, designed to teach coping strategies and/or inert content, depending on the study participant's randomization assignment. The FoRtitude study will examine whether three coping strategies (relaxation training, cognitive restructuring, worry practice) are more effective than general health-related content in reducing fear of cancer recurrence.

Przegląd badań

Status

Zakończony

Warunki

Interwencja / Leczenie

Szczegółowy opis

The purpose of the FoRtitude trial is to develop and evaluate a targeted eHealth intervention designed to teach breast cancer survivors (BCS) coping strategies to manage fear about cancer recurrence (FoR). FoRtitude, a web-based program with interactive text messaging capabilities, was created to deliver a targeted intervention for BCS with moderate to severe FoR. FoRtitude consists of didactic content presented in written and video-based formats and interactive tools, designed to teach coping strategies. Commonly used cognitive behavior therapy (CBT) techniques were tailored to the management of FoR and included diaphragmatic breathing and relaxation, cognitive restructuring, and scheduled worry practice. Participants are encouraged to use the FoRtitude site several times per week over a period of 4 weeks. The investigators employed principles of user-centered design to create the FoRtitude website and incorporated feedback from 17 BCS to refine site content and improve FoRtitude usability.

After refining the FoRtitude site, the investigators will conduct a randomized controlled trial using the Multiphase Optimization Strategy (MOST) to individually evaluate three coping strategies; each coping strategy will be compared to health management content. Inert content includes general health information and managing comorbid illnesses, information on general nutrition, and information on nutritional topics of interest to BCS. Half of the participants will be randomized to receive telecoaching, which included 3-4 telephone-based brief sessions with a motivational interviewer, aimed at improving adherence to use of the FoRtitude site. Participants will complete questionnaires at baseline, 4 weeks (immediately after completing the FoRtitude site) and at 8 weeks.

Study hypotheses:

BCS randomized to Relaxation training will report a greater reduction in fear of cancer recurrence from pre-post intervention than BCS randomized to inert (health management) content
BCS randomized to Cognitive restructuring will report a greater reduction in fear of cancer recurrence from pre-post intervention than BCS randomized to inert (health management) content
BCS randomized to Scheduled Worry practice will report a greater reduction in fear of cancer recurrence from pre-post intervention than BCS randomized to inert (health management) content
BCS randomized to receive Telecoaching will demonstrate higher adherence to using the FoRtitude site and will report a greater reduction in fear of cancer recurrence from pre-post intervention compared to BCS randomized to no Telecoaching
BCS randomized to a higher number of coping strategies will report a greater reduction in fear of cancer recurrence from pre-post intervention than BCS randomized to receive all inert content or fewer coping strategies (dose-response effect)

Typ studiów

Interwencyjne

Zapisy (Rzeczywisty)

215

Faza

Nie dotyczy

Kryteria uczestnictwa

Badacze szukają osób, które pasują do określonego opisu, zwanego kryteriami kwalifikacyjnymi. Niektóre przykłady tych kryteriów to ogólny stan zdrowia danej osoby lub wcześniejsze leczenie.

Kryteria kwalifikacji

Wiek uprawniający do nauki

18 lat i starsze (Dorosły, Starszy dorosły)

Akceptuje zdrowych ochotników

Tak

Płeć kwalifikująca się do nauki

Kobieta

Opis

Inclusion Criteria:

Female
Diagnosis of breast cancer, non-metastatic, stage I-III
Completed primary treatment for breast cancer (surgery, chemotherapy and/or radiation therapy, current hormonal treatment allowable)
No current evidence of disease
1. Greater than 1 year post treatment (for phase I interviews and usability testing)
2. Between 1 and 10 years post-treatment (for Phase I field testing and Phase II)
Good overall functional status as evidenced by ECOG Performance Status < 3
At least 18 years of age (for Phase I only)
At least 19 years of age (for Phase 2 only)
Able to speak and read English
Able to provide informed consent
Clinically significant FoR, measured by the 9-item FCRI severity scale using established cut-off
a. Patients may be eligible for Phase I and Phase IV of the study regardless of their FCRI score
Cellular telephone with SMS messaging capability and access to a computer with broadband Internet access
Self-reported familiarity with the Internet per Internet Usage Patterns Measure
For Phase III, participants must have participated in Phase II
For Phase IV, participants must be a self-identified African American breast cancer survivor that is willing to review site content and provide feedback in addition to meeting inclusion criteria above (with exception of FCRI severity scale score)

Exclusion Criteria:

Visual, hearing, voice, or motor impairment that would prevent completion of study procedures
Diagnosed with a psychotic disorder, bipolar disorder, dissociative disorder, or other diagnosis for which participation in this trial is either inappropriate or dangerous
Hazardous substance or alcohol use
Suicidal ideation, plan, intent
Dementia
Or if the participant is deemed ineligible by the investigators for reasons not otherwise specified.

Plan studiów

Ta sekcja zawiera szczegółowe informacje na temat planu badania, w tym sposób zaprojektowania badania i jego pomiary.

Jak projektuje się badanie?

Szczegóły projektu

Główny cel: Leczenie podtrzymujące
Przydział: Randomizowane
Model interwencyjny: Przypisanie czynnikowe
Maskowanie: Potroić

Liczba ramion

Broń i interwencje

Grupa uczestników / Arm	Interwencja / Leczenie
Eksperymentalny: Group 1 Participants were exposed to the following conditions: general health for week 1, diet-general information for week 2, and diet-BCSS information (breast cancer survivor-specific) for week 3. Telephone coaching was given.	Inny: Telephone coaching BCS will receive 5 TeleCoaching calls over a period of 4 weeks, to include one introductory phone call, followed by 4 calls focused each week on the current CSM; if the participant is not randomized to a CSM, TeleCoaching will provide reflective listening and encouragement. Inny: Usual care Includes general health, diet-general information and diet-BCSS (breast cancer survivor-specific) information.
Eksperymentalny: Group 2 Participants were exposed to the one of the following usual care conditions: general health for week 1, diet-general information for week 2, and diet-BCSS information (breast cancer survivor-specific) for week 3.	Inny: Usual care Includes general health, diet-general information and diet-BCSS (breast cancer survivor-specific) information.
Eksperymentalny: Group 3 Participants were exposed to the following conditions: cognitive restructuring for week 1, general health for week 2, and diet-general information and diet-BCSS information (breast cancer survivor-specific) for week 3. Telephone coaching was given.	Inny: Telephone coaching BCS will receive 5 TeleCoaching calls over a period of 4 weeks, to include one introductory phone call, followed by 4 calls focused each week on the current CSM; if the participant is not randomized to a CSM, TeleCoaching will provide reflective listening and encouragement. Inny: Usual care Includes general health, diet-general information and diet-BCSS (breast cancer survivor-specific) information. Inny: Cognitive restructuring Education on the thought-emotion connection and exercises designed to better understand cognitions associated with increased anxiety and tools to evaluate and replace anxiety-generating cognitions. Includes an interactive tool (thought record) participants complete to facilitate this process.
Eksperymentalny: Group 4 Participants were exposed to the following conditions: cognitive restructuring for week 1, general health for week 2, and diet-general information and diet-BCSS information (breast cancer survivor-specific) for week 3.	Inny: Usual care Includes general health, diet-general information and diet-BCSS (breast cancer survivor-specific) information. Inny: Cognitive restructuring Education on the thought-emotion connection and exercises designed to better understand cognitions associated with increased anxiety and tools to evaluate and replace anxiety-generating cognitions. Includes an interactive tool (thought record) participants complete to facilitate this process.
Eksperymentalny: Group 5 Participants were exposed to the following conditions: scheduled worry practice for week 1, general health for week 2, and diet-general information and diet-BCSS information (breast cancer survivor-specific) for week 3. Telephone coaching was given.	Inny: Telephone coaching BCS will receive 5 TeleCoaching calls over a period of 4 weeks, to include one introductory phone call, followed by 4 calls focused each week on the current CSM; if the participant is not randomized to a CSM, TeleCoaching will provide reflective listening and encouragement. Inny: Usual care Includes general health, diet-general information and diet-BCSS (breast cancer survivor-specific) information. Inny: Scheduled worry practice Education on the association between avoidance and increased anxiety, and instructions on actively thinking about feared events to reduce avoidance and engage healthy coping strategies. Interactive tool includes a video-based guided worry practice session and an interactive worksheet and timer.
Eksperymentalny: Group 6 Participants were exposed to the following conditions: scheduled worry practice for week 1, general health for week 2, and diet-general information and diet-BCSS information (breast cancer survivor-specific) for week 3.	Inny: Usual care Includes general health, diet-general information and diet-BCSS (breast cancer survivor-specific) information. Inny: Scheduled worry practice Education on the association between avoidance and increased anxiety, and instructions on actively thinking about feared events to reduce avoidance and engage healthy coping strategies. Interactive tool includes a video-based guided worry practice session and an interactive worksheet and timer.
Eksperymentalny: Group 7 Participants were exposed to the following conditions: cognitive restructuring for week 1, worry practice for week 2, and General Health and Diet (General and BCSS) for week 3. Telephone coaching was given.	Inny: Telephone coaching BCS will receive 5 TeleCoaching calls over a period of 4 weeks, to include one introductory phone call, followed by 4 calls focused each week on the current CSM; if the participant is not randomized to a CSM, TeleCoaching will provide reflective listening and encouragement. Inny: Usual care Includes general health, diet-general information and diet-BCSS (breast cancer survivor-specific) information. Inny: Cognitive restructuring Education on the thought-emotion connection and exercises designed to better understand cognitions associated with increased anxiety and tools to evaluate and replace anxiety-generating cognitions. Includes an interactive tool (thought record) participants complete to facilitate this process. Inny: Scheduled worry practice Education on the association between avoidance and increased anxiety, and instructions on actively thinking about feared events to reduce avoidance and engage healthy coping strategies. Interactive tool includes a video-based guided worry practice session and an interactive worksheet and timer.
Eksperymentalny: Group 8 Participants were exposed to the following conditions: cognitive restructuring for week 1, scheduled worry practice for week 2, and General Health and Diet (General and BCSS) for week 3.	Inny: Usual care Includes general health, diet-general information and diet-BCSS (breast cancer survivor-specific) information. Inny: Cognitive restructuring Education on the thought-emotion connection and exercises designed to better understand cognitions associated with increased anxiety and tools to evaluate and replace anxiety-generating cognitions. Includes an interactive tool (thought record) participants complete to facilitate this process. Inny: Scheduled worry practice Education on the association between avoidance and increased anxiety, and instructions on actively thinking about feared events to reduce avoidance and engage healthy coping strategies. Interactive tool includes a video-based guided worry practice session and an interactive worksheet and timer.
Eksperymentalny: Group 9 Participants were exposed to the following conditions: Diaphragmatic breathing and relaxation for week 1, general health for week 2, and Diet - General and BCSS for week 3. Telephone coaching was given.	Inny: Telephone coaching BCS will receive 5 TeleCoaching calls over a period of 4 weeks, to include one introductory phone call, followed by 4 calls focused each week on the current CSM; if the participant is not randomized to a CSM, TeleCoaching will provide reflective listening and encouragement. Inny: Usual care Includes general health, diet-general information and diet-BCSS (breast cancer survivor-specific) information. Inny: Diaphragmatic breathing and relaxation Education on physiological effects of anxiety, instructions in diaphragmatic breathing and relaxation techniques, and audio-recordings 5-15 minutes in length that provide guided relaxation exercises (autogenic, imagery-based and progressive muscle relaxation).
Eksperymentalny: Group 10 Participants were exposed to the following conditions: Diaphragmatic breathing and relaxation for week 1, general health for week 2, and Diet - General and BCSS for week 3.	Inny: Usual care Includes general health, diet-general information and diet-BCSS (breast cancer survivor-specific) information. Inny: Diaphragmatic breathing and relaxation Education on physiological effects of anxiety, instructions in diaphragmatic breathing and relaxation techniques, and audio-recordings 5-15 minutes in length that provide guided relaxation exercises (autogenic, imagery-based and progressive muscle relaxation).
Eksperymentalny: Group 11 Participants were exposed to the following conditions: Diaphragmatic breathing and relaxation for week 1, cognitive restructuring for week 2, and General health and Diet (General and BCSS) for week 3. Telephone coaching was given.	Inny: Telephone coaching BCS will receive 5 TeleCoaching calls over a period of 4 weeks, to include one introductory phone call, followed by 4 calls focused each week on the current CSM; if the participant is not randomized to a CSM, TeleCoaching will provide reflective listening and encouragement. Inny: Usual care Includes general health, diet-general information and diet-BCSS (breast cancer survivor-specific) information. Inny: Cognitive restructuring Education on the thought-emotion connection and exercises designed to better understand cognitions associated with increased anxiety and tools to evaluate and replace anxiety-generating cognitions. Includes an interactive tool (thought record) participants complete to facilitate this process. Inny: Diaphragmatic breathing and relaxation Education on physiological effects of anxiety, instructions in diaphragmatic breathing and relaxation techniques, and audio-recordings 5-15 minutes in length that provide guided relaxation exercises (autogenic, imagery-based and progressive muscle relaxation).
Eksperymentalny: Group 12 Participants were exposed to the following conditions: Diaphragmatic breathing and relaxation for week 1, cognitive restructuring for week 2, and General health and Diet (General and BCSS) for week 3.	Inny: Usual care Includes general health, diet-general information and diet-BCSS (breast cancer survivor-specific) information. Inny: Cognitive restructuring Education on the thought-emotion connection and exercises designed to better understand cognitions associated with increased anxiety and tools to evaluate and replace anxiety-generating cognitions. Includes an interactive tool (thought record) participants complete to facilitate this process. Inny: Diaphragmatic breathing and relaxation Education on physiological effects of anxiety, instructions in diaphragmatic breathing and relaxation techniques, and audio-recordings 5-15 minutes in length that provide guided relaxation exercises (autogenic, imagery-based and progressive muscle relaxation).
Eksperymentalny: Group 13 Participants were exposed to the following conditions: Diaphragmatic breathing and relaxation for week 1, worry practice for week 2, and General health and Diet (General and BCSS) for week 3. Telephone coaching was given.	Inny: Telephone coaching BCS will receive 5 TeleCoaching calls over a period of 4 weeks, to include one introductory phone call, followed by 4 calls focused each week on the current CSM; if the participant is not randomized to a CSM, TeleCoaching will provide reflective listening and encouragement. Inny: Usual care Includes general health, diet-general information and diet-BCSS (breast cancer survivor-specific) information. Inny: Scheduled worry practice Education on the association between avoidance and increased anxiety, and instructions on actively thinking about feared events to reduce avoidance and engage healthy coping strategies. Interactive tool includes a video-based guided worry practice session and an interactive worksheet and timer. Inny: Diaphragmatic breathing and relaxation Education on physiological effects of anxiety, instructions in diaphragmatic breathing and relaxation techniques, and audio-recordings 5-15 minutes in length that provide guided relaxation exercises (autogenic, imagery-based and progressive muscle relaxation).
Eksperymentalny: Group 14 Participants were exposed to the following conditions: Diaphragmatic breathing and relaxation for week 1, scheduled worry practice for week 2, and General health and Diet (General and BCSS) for week 3.	Inny: Usual care Includes general health, diet-general information and diet-BCSS (breast cancer survivor-specific) information. Inny: Scheduled worry practice Education on the association between avoidance and increased anxiety, and instructions on actively thinking about feared events to reduce avoidance and engage healthy coping strategies. Interactive tool includes a video-based guided worry practice session and an interactive worksheet and timer. Inny: Diaphragmatic breathing and relaxation Education on physiological effects of anxiety, instructions in diaphragmatic breathing and relaxation techniques, and audio-recordings 5-15 minutes in length that provide guided relaxation exercises (autogenic, imagery-based and progressive muscle relaxation).
Eksperymentalny: Group 15 Participants were exposed to the following conditions: Diaphragmatic breathing and relaxation for week 1, worry practice for week 2, and cognitive restructuring for week 3. Telephone coaching was given.	Inny: Telephone coaching BCS will receive 5 TeleCoaching calls over a period of 4 weeks, to include one introductory phone call, followed by 4 calls focused each week on the current CSM; if the participant is not randomized to a CSM, TeleCoaching will provide reflective listening and encouragement. Inny: Cognitive restructuring Education on the thought-emotion connection and exercises designed to better understand cognitions associated with increased anxiety and tools to evaluate and replace anxiety-generating cognitions. Includes an interactive tool (thought record) participants complete to facilitate this process. Inny: Scheduled worry practice Education on the association between avoidance and increased anxiety, and instructions on actively thinking about feared events to reduce avoidance and engage healthy coping strategies. Interactive tool includes a video-based guided worry practice session and an interactive worksheet and timer. Inny: Diaphragmatic breathing and relaxation Education on physiological effects of anxiety, instructions in diaphragmatic breathing and relaxation techniques, and audio-recordings 5-15 minutes in length that provide guided relaxation exercises (autogenic, imagery-based and progressive muscle relaxation).
Eksperymentalny: Group 16 Participants were exposed to the following conditions: Diaphragmatic breathing and relaxation for week 1, scheduled worry practice for week 2, and cognitive restructuring for week 3.	Inny: Cognitive restructuring Education on the thought-emotion connection and exercises designed to better understand cognitions associated with increased anxiety and tools to evaluate and replace anxiety-generating cognitions. Includes an interactive tool (thought record) participants complete to facilitate this process. Inny: Scheduled worry practice Education on the association between avoidance and increased anxiety, and instructions on actively thinking about feared events to reduce avoidance and engage healthy coping strategies. Interactive tool includes a video-based guided worry practice session and an interactive worksheet and timer. Inny: Diaphragmatic breathing and relaxation Education on physiological effects of anxiety, instructions in diaphragmatic breathing and relaxation techniques, and audio-recordings 5-15 minutes in length that provide guided relaxation exercises (autogenic, imagery-based and progressive muscle relaxation).

Co mierzy badanie?

Podstawowe miary wyniku

Miara wyniku	Opis środka	Ramy czasowe
Fear of Cancer Recurrence Inventory (FCRI) total score (minus Coping and Reassurance subscales) Ramy czasowe: Baseline to Week 8 change score	Questionnaire aims to better understand the experience of worries about cancer recurrence. Scaled from 1-4 with 4 being "all the time" and 1 being "never". The FCRI is the only FoR measure validated using interview to define 'caseness' and has demonstrated reliability and validity with English speaking survivors. FCRI total score to be calculated without including the Coping and Reassurance subscales defined a priori and determined by FoR theoretical model.	Baseline to Week 8 change score

Miary wyników drugorzędnych

Miara wyniku	Opis środka	Ramy czasowe
Impact of Events Scale - Revised Ramy czasowe: Baseline to Week 8 change score	Questionnaire to assess illness-related distress and post-truamatic type anxiety	Baseline to Week 8 change score
Concerns about Recurrence Scale (CARS) - 4 item severity score Ramy czasowe: Baseline to Week 8 change score	Questionnaire to assess concerns about recurrence among BCS	Baseline to Week 8 change score
PROMIS Anxiety Computer adaptive test Ramy czasowe: Baseline to Week 8 change score	Questions administered using a computer adaptive test-based algorithm to assess overall anxiety	Baseline to Week 8 change score
PROMIS Depression Computer adaptive test Ramy czasowe: Baseline to Week 8 change score	Questions administered using a computer adaptive test-based algorithm to assess depression	Baseline to Week 8 change score
PROMIS Sleep Disturbance Computer adaptive test Ramy czasowe: Baseline to Week 8 change score	Questions administered using a computer adaptive test-based algorithm to assess sleep disturbances	Baseline to Week 8 change score
PROMIS Fatigue Computer adaptive test Ramy czasowe: Baseline to Week 8 change score	Questions administered using a computer adaptive test-based algorithm to assess fatigue	Baseline to Week 8 change score
PROMIS Global Health Ramy czasowe: Baseline to Week 8 change score	Questionnaire to assess overall health and health-related quality of life	Baseline to Week 8 change score
PROMIS Applied Cognition Computer adaptive test Ramy czasowe: Baseline to Week 8 change score	Questions administered using a computer adaptive test-based algorithm to assess patient-reported cognitive impairments	Baseline to Week 8 change score
Breast Cancer Self-Efficacy scale (BCSE) Ramy czasowe: Baseline to Week 8 change score	Questionnaire to assess confidence in one's ability to manage breast cancer	Baseline to Week 8 change score

Współpracownicy i badacze

Tutaj znajdziesz osoby i organizacje zaangażowane w to badanie.

Sponsor

Wake Forest University Health Sciences

Współpracownicy

National Cancer Institute (NCI)

Śledczy

Główny śledczy: Lynne Wagner, Ph.D., Wake Forest University Health Sciences

Daty zapisu na studia

Daty te śledzą postęp w przesyłaniu rekordów badań i podsumowań wyników do ClinicalTrials.gov. Zapisy badań i zgłoszone wyniki są przeglądane przez National Library of Medicine (NLM), aby upewnić się, że spełniają określone standardy kontroli jakości, zanim zostaną opublikowane na publicznej stronie internetowej.

Główne daty studiów

Rozpoczęcie studiów (Rzeczywisty)

1 marca 2014

Zakończenie podstawowe (Rzeczywisty)

5 grudnia 2015

Ukończenie studiów (Rzeczywisty)

5 grudnia 2015

Daty rejestracji na studia

Pierwszy przesłany

20 grudnia 2017

Pierwszy przesłany, który spełnia kryteria kontroli jakości

20 grudnia 2017

Pierwszy wysłany (Rzeczywisty)

28 grudnia 2017

Aktualizacje rekordów badań

Ostatnia wysłana aktualizacja (Rzeczywisty)

30 kwietnia 2018

Ostatnia przesłana aktualizacja, która spełniała kryteria kontroli jakości

27 kwietnia 2018

Ostatnia weryfikacja

1 kwietnia 2018

Więcej informacji

Terminy związane z tym badaniem

Słowa kluczowe

Dodatkowe istotne warunki MeSH

Inne numery identyfikacyjne badania

IRB00036679
1R21CA173193-01A1 (Grant/umowa NIH USA)

Informacje o lekach i urządzeniach, dokumenty badawcze

Bada produkt leczniczy regulowany przez amerykańską FDA

Nie

Bada produkt urządzenia regulowany przez amerykańską FDA

Nie

Te informacje zostały pobrane bezpośrednio ze strony internetowej clinicaltrials.gov bez żadnych zmian. Jeśli chcesz zmienić, usunąć lub zaktualizować dane swojego badania, skontaktuj się z register@clinicaltrials.gov. Gdy tylko zmiana zostanie wprowadzona na stronie clinicaltrials.gov, zostanie ona automatycznie zaktualizowana również na naszej stronie internetowej .

Badania kliniczne na Rak piersi

University of Michigan Rogel Cancer Center
National Cancer Institute (NCI)

Jeszcze nie rekrutacja

Internetowy program (Kindred) mający na celu poprawę zrozumienia genetycznego ryzyka zachorowania na nowotwory oraz testów genetycznych w rodzinach Afroamerykanów

Syndrom Lyncha | Dziedziczny zespół nowotworowy | BRCA1-Related Hereditary Breast and Ovarian Cancer Syndrome | BRCA2-Related Hereditary Breast and Ovarian Cancer Syndrome

Stany Zjednoczone
University of Chicago

Jeszcze nie rekrutacja

Trastuzumab deruxtecan w celu leczenia HER2 + nowo zdiagnozowanych przerzutowych nowotworów GI

HER2 Pozytywne nowo zdiagnozowane przerzuty przełyku, żołądka, GEJ Cancer Pacjenci ze statusem wydajności ECOG 2
Emory University
National Cancer Institute (NCI)

Wycofane

Radiochirurgia stereotaktyczna z użyciem abemacyklibu, rybocyklibu lub palbocyklibu w leczeniu pacjentów z rakiem piersi z dodatnim receptorem hormonalnym i przerzutami do mózgu

Prognostyczny rak piersi IV stopnia AJCC v8 | Przerzutowy nowotwór złośliwy w mózgu | Przerzutowy rak piersi | Anatomiczny IV stopień raka piersi American Joint Committee on Cancer (AJCC) v8
Jonsson Comprehensive Cancer Center

Zakończony

Wpływ inhibitorów sygnalizacji receptora androgenowego na obrazowanie PET/CT 68Ga-PSMA-11 u pacjentów z opornym na kastrację rakiem prostaty

Rak prostaty oporny na kastrację | Przerzutowy rak prostaty | Stadium IVA raka prostaty AJCC v8 | Rak prostaty w stadium IVB AJCC v8 | Rak prostaty w stadium IV American Joint Committee on Cancer (AJCC) v8

Stany Zjednoczone
Jonsson Comprehensive Cancer Center
Eli Lilly and Company; Genentech, Inc.

Aktywny, nie rekrutujący

Necytumumab i trastuzumab w skojarzeniu z ozymertynibem w leczeniu opornego na leczenie receptora naskórkowego czynnika wzrostu (EGFR) w stadium IV z mutacją niedrobnokomórkowego raka płuca

Niedrobnokomórkowy rak płuc z przerzutami | Oporny na leczenie niedrobnokomórkowy rak płuc | Rak płuca w stadium IV American Joint Committee on Cancer (AJCC) v8 | Rak płuc w stadium IVA AJCC v8 | Rak płuc w stadium IVB AJCC v8

Stany Zjednoczone
Jonsson Comprehensive Cancer Center

Rekrutacyjny

Biopsje sterowane obrazem w celu identyfikacji mechanizmów oporności u pacjentów z opornym na kastrację rakiem gruczołu krokowego z przerzutami, leczonych radioligandem 177Lu-PSMA

Rak prostaty oporny na kastrację | Przerzutowy rak prostaty | Stadium IVA raka prostaty AJCC v8 | Rak prostaty w stadium IVB AJCC v8 | Rak prostaty w stadium IV American Joint Committee on Cancer (AJCC) v8

Stany Zjednoczone
Jonsson Comprehensive Cancer Center

Zakończony

68Ga-PSMA-11 PET/CT do diagnostyki przerzutów do kości u pacjentów z rakiem prostaty i progresji biochemicznej podczas terapii deprywacji androgenów

Biochemicznie nawracający rak prostaty | Przerzutowy rak prostaty | Nowotwór złośliwy z przerzutami w kości | Stadium IVA raka prostaty AJCC v8 | Rak prostaty w stadium IVB AJCC v8 | Rak prostaty w stadium IV American Joint Committee on Cancer (AJCC) v8

Stany Zjednoczone
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Zakończony

Stereotaktyczna radioterapia ciała w leczeniu pacjentów z rakiem prostaty wysokiego ryzyka poddawanych zabiegom chirurgicznym

Gruczolakorak gruczołu krokowego III stopnia AJCC v7 | Gruczolakorak gruczołu krokowego II stopnia AJCC v7 | Stopień I gruczolakoraka gruczołu krokowego American Joint Committee on Cancer (AJCC) v7

Stany Zjednoczone
NRG Oncology
National Cancer Institute (NCI)

Zakończony

Testowanie, czy leczenie przerzutów raka piersi za pomocą operacji lub promieniowania w dużych dawkach poprawia przeżycie

Anatomiczny rak piersi IV stadium AJCC v8 | Prognostyczny rak piersi IV stopnia AJCC v8 | Nowotwór złośliwy z przerzutami w kości | Przerzutowy nowotwór złośliwy w węzłach chłonnych | Przerzutowy nowotwór złośliwy w wątrobie | Przerzutowy rak piersi | Przerzutowy nowotwór złośliwy w płucach | Nowotwór... i inne warunki

Stany Zjednoczone, Kanada, Arabia Saudyjska, Korea Południowa
National Cancer Institute (NCI)

Zakończony

Navitoclax i Vistusertib w leczeniu pacjentów z nawrotowym rakiem drobnokomórkowym płuca i innymi guzami litymi

Oporny na leczenie złośliwy nowotwór lity | Nawracający złośliwy nowotwór lity | Przerzutowy złośliwy nowotwór lity | Nieoperacyjny lity nowotwór | Nawracający rak drobnokomórkowy płuca | Stopień IIIA Rak drobnokomórkowy płuca AJCC v7 | Etap IIIB Rak drobnokomórkowy płuca AJCC v7 | Rak drobnokomórkowy... i inne warunki

Stany Zjednoczone

Badania kliniczne na Telephone coaching

Boston Medical Center
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Zakończony

Wspierane przez IT wczesne leczenie nadwagi u dzieci (HEAT)

Dziecięca otyłość | Interwencja otyłości oparta na technologii

Stany Zjednoczone
Mayo Clinic

Zakończony

Wpływ profesjonalnego coachingu na wczesne kariery akademickich lekarzy medycyny ratunkowej

Stres | Lęk | Przywództwo | Rola zawodowa | Cele | Dobre samopoczucie | Rola lekarza | Wypalenie zawodowe | Rozwój, człowiek

Stany Zjednoczone
Rigshospitalet, Denmark
Gilead Sciences

Zakończony

Interwencja coachingowa dla młodych dorosłych z mukowiscydozą

Mukowiscydoza

Dania
VA Office of Research and Development
VA Palo Alto Health Care System; Atlanta VA Medical Center; Malcom Randall VA... i inni współpracownicy

Rekrutacyjny

Strategie opieki wirtualnej poprawiające udział weteranów w rehabilitacji kardiologicznej (IMPACT)

Choroby układu krążenia

Stany Zjednoczone
Creighton University
DexCom, Inc.

Zakończony

Telezdrowotny coaching rodzinny z cukrzycą typu 1

Cukrzyca typu 1

Stany Zjednoczone
Slovak Academy of Sciences
University Hospital Bratislava Comenius University; Kempelen Institute of Inteligent...

Rekrutacyjny

Digitalizacja spersonalizowanego zarządzania ryzykiem zdrowotnym (DIG4HEALTH)

Otyłość | Przedsoczowość

Słowacja
Food and Health Bureau, Hong Kong

Rekrutacyjny

Trener wspierany przez mZdrowie

Czynniki ryzyka chorób serca

Hongkong
University of Maryland, Baltimore
National Institute on Aging (NIA)

Zakończony

Aktywacja behawioralna, odżywianie i interwencja w zakresie aktywności

HIV

Stany Zjednoczone
University of Central Florida

Zakończony

Wskazówki werbalne a podejście oparte na ograniczeniu do nauczania zamachu z kettlebell.

Zaburzenia ruchowe | Czułość mięśni

Stany Zjednoczone
Utah State University

Zakończony

Pilotażowa ocena coachingu wsparcia rówieśniczego w celu zwiększenia przestrzegania samopomocy online w zakresie zdrowia psychicznego uczelni

Przestrzeganie leczenia

Stany Zjednoczone

Targeted eHealth Intervention to Reduce Fear of Recurrence Among Breast Cancer Survivors (FoRtitude)

Targeted eHealth Intervention to Reduce Fear of Recurrence Among Breast Cancer Survivors: The FoRtitude Trial

Przegląd badań

Status

Warunki

Interwencja / Leczenie

Szczegółowy opis

Typ studiów

Zapisy (Rzeczywisty)

Faza

Kryteria uczestnictwa

Kryteria kwalifikacji

Wiek uprawniający do nauki

Akceptuje zdrowych ochotników

Płeć kwalifikująca się do nauki

Opis

Plan studiów

Jak projektuje się badanie?

Szczegóły projektu

Liczba ramion

Broń i interwencje

Grupa uczestników / Arm

Interwencja / Leczenie

Co mierzy badanie?

Podstawowe miary wyniku

Miara wyniku

Opis środka

Ramy czasowe

Miary wyników drugorzędnych

Miara wyniku

Opis środka

Ramy czasowe

Współpracownicy i badacze

Sponsor

Współpracownicy

Śledczy

Daty zapisu na studia

Główne daty studiów

Rozpoczęcie studiów (Rzeczywisty)

Zakończenie podstawowe (Rzeczywisty)

Ukończenie studiów (Rzeczywisty)

Daty rejestracji na studia

Pierwszy przesłany

Pierwszy przesłany, który spełnia kryteria kontroli jakości

Pierwszy wysłany (Rzeczywisty)

Aktualizacje rekordów badań

Ostatnia wysłana aktualizacja (Rzeczywisty)

Ostatnia przesłana aktualizacja, która spełniała kryteria kontroli jakości

Ostatnia weryfikacja

Więcej informacji

Terminy związane z tym badaniem

Słowa kluczowe

Dodatkowe istotne warunki MeSH

Inne numery identyfikacyjne badania

Informacje o lekach i urządzeniach, dokumenty badawcze

Bada produkt leczniczy regulowany przez amerykańską FDA

Bada produkt urządzenia regulowany przez amerykańską FDA

Badania kliniczne na Rak piersi

Badania kliniczne na Telephone coaching

Wyszukaj podobne próby

Sponsorzy i współpracownicy

Warunki medyczne

Interwencje lekowe

CROs by country

CROs in Sri Lanka

Warunki

Rzadkie choroby

Interwencje lekowe

Suplementy diety

Sponsor / Współpracownicy

Lokalizacje