Swiss Hospital started a new clinical trial of Anatomic Versus Reverse Shoulder Arthroplasty for Primary Glenohumeral Osteoarthritis

Photo by Morgan Vander Hart

La Tour Hospital is enrolling patients into the clinical trial investigating Anatomic TSA vs RTSA for Glenohumeral Arthritis.

There are no published prospective studies that compared 2-year functional outcomes of RTSA and anatomic TSA for the treatment of primary glenohumeral osteoarthritis with intact rotator cuffs and no excessive glenoid retroversion. The primary goal of this study is to determine whether RTSA have at least as good results as anatomic TSA (non-inferiority), in patients with glenohumeral osteoarthritis, without rotator cuff tears nor significant glenoid retroversion.
Total anatomic shoulder arthroplasty (TSA) is an effective treatment of severe glenohumeral osteoarthritis, with significant improvement in shoulder pain and function. Concerns about glenoid loosening, associated with difficult revision procedures and disappointing outcomes, have however been raised.

Reverse total shoulder arthroplasty (RTSA) was designed with a medialized center of rotation to treat cuff tear arthropathy. Favorable early reports led to the expansion of primary indications of RTSA to proximal humeral fractures as well as osteoarthritis with poor glenoid bone stock. Recent reports revealed excellent clinical results of RTSA for primary glenohumeral arthropathy with intact rotator cuff and a low rate of complications.

The trial is designed to enrol male and female 65 years to 85 years and is being conducted in the La Tour Hospital, Meyrin, Switzerland.

The study population that can be enrolled into this study includes patients with primary glenohumeral arthritis, intact rotator cuff and no important glenoid bone loss.

Among the exclusion criteria are:

• Full thickness rotator cuff tear.
• Chronic locked dislocation.
• Rheumatoid arthritis.
• Axillary nerve damage

and others.

This page provides a more detailed overview of this clinical trial: https://ichgcp.net/clinical-trials-registry/NCT04629391.