- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00043563
Cognitive Behavioral Treatment of Pediatric Trichotillomania
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
TTM is a persistent impulse control disorder in which the individual acts on urges to pull out his or her own hair. Onset typically occurs by adolescence, and TTM is often associated with significant functional impairment and distress. CBT is a type of psychotherapy designed to change problematic behaviors and thinking. It includes self-monitoring of hair-pulling urges and homework assignments to practice the use of cognitive and behavioral strategies.
Participants are assigned randomly to receive either CBT or AC for 8 weeks. Participants assigned to CBT receive weekly 1-hour sessions of CBT for 8 weeks; participants assigned to AC receive 6 telephone contacts and 2 in-person sessions for 8 weeks. After 8 weeks, CBT participants who respond to treatment enter Phase II, which lasts an additional 8 weeks and includes 4 in-person maintenance sessions. AC participants who are still symptomatic after 8 weeks are offered CBT.
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Contacts and Locations
Study Locations
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Pennsylvania
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Philadelphia, Pennsylvania, United States, 19104
- Center for the Treatment and Study of Anxiety
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-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- Primary diagnosis of Trichotillomania
- Minimum symptom duration of 6 months
- Presence of a stable parent or guardian
Exclusion Criteria:
- Other primary psychiatric diagnosis
- Bipolar illness, pervasive developmental disorder, thought disorder, current major depression, ADD/ADHD
- Concurrent psychotherapy
- Currently receiving psychotropic medications
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
National Institute of Mental Health (NIMH) Trichotillomania Severity Scale
Time Frame: 1 week
|
Semi-structured interview about hair-pulling and related symptoms
|
1 week
|
Collaborators and Investigators
Sponsor
Collaborators
Publications and helpful links
General Publications
- Franklin ME, Edson AL, Ledley DA, Cahill SP. Behavior therapy for pediatric trichotillomania: a randomized controlled trial. J Am Acad Child Adolesc Psychiatry. 2011 Aug;50(8):763-71. doi: 10.1016/j.jaac.2011.05.009. Epub 2011 Jul 1.
- Franklin ME, Edson AL, Freeman JB. Behavior therapy for pediatric trichotillomania: Exploring the effects of age on treatment outcome. Child Adolesc Psychiatry Ment Health. 2010 Jun 28;4:18. doi: 10.1186/1753-2000-4-18.
Study record dates
Study Major Dates
Study Start
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- R21MH061457 (U.S. NIH Grant/Contract)
- DSIR CT-S
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Trichotillomania
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Johns Hopkins UniversityRecruitingTrichotillomania | Trichotillomania (Hair-Pulling Disorder) | Hair PullingUnited States
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University of ChicagoNot yet recruitingTrichotillomania (Hair-Pulling Disorder) | DermatillomaniaUnited States
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University of ChicagoCompletedTrichotillomania (Hair-Pulling Disorder) | DermatillomaniaUnited States
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University of ChicagoRecruitingTrichotillomania (Hair-Pulling Disorder) | Skin-PickingUnited States
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American UniversityCompletedTrichotillomania (Hair-Pulling Disorder) | Skin-PickingUnited States
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Yale UniversityNeurocrine BiosciencesRecruitingTrichotillomania (Hair-Pulling Disorder)United States
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HabitAware Inc.National Institute of Mental Health (NIMH); Marquette UniversityCompletedTrichotillomaniaUnited States
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University of Wisconsin, MilwaukeeCompleted
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University of PennsylvaniaNational Institute of Mental Health (NIMH)CompletedTrichotillomaniaUnited States
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University of Sao PauloCompleted
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Henry M. Jackson Foundation for the Advancement...National Alliance for Research on Schizophrenia and DepressionCompletedSuicide, AttemptedUnited States
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Qazvin University Of Medical SciencesUnknownInsomniaIran, Islamic Republic of
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University of PittsburghEmory UniversityCompletedStress, Psychological | Metabolic Disturbance | Disorder of Endocrine Ovary | Hypersecretion; CortisolUnited States
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Karolinska InstitutetCompletedFunctional Dyspepsia | Functional Abdominal Pain | Irritable Bowel Syndrome (IBS) | Functional Gastrointestinal Disorders (FGID) | FGID According to the Rome III CriteriaSweden