Glycemic Index and Polyphenol Bioavailability of Potatoes (GI)

January 14, 2011 updated by: Guelph Food Research Centre

A Trial to Measure the Glycemic Index and Polyphenol Bioavailability of Four Different Varieties of Potato.

The purpose of this study is to determine the glycemic index of four varieties of potatoes and to determine the bioavailability of polyphenols contained in these potatoes.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Ten healthy persons will have a fasting blood sample drawn and asked to randomly consume a 50g glucose drink (2 occasions), or 50g carbohydrate equivalent of cooked purple, red, yellow and white potatoes. Further blood samples will be obtained at 15,30, 45, 60, 90, 120, 180, 240 mins. Bloods from the first 2 hours will be analyzed for glucose and insulin to determine the glycemic response. Hourly blood samples will be analyzed for polyphenol to determine the bioavailability of polyphenols from the different potato variety. Urine samples will be collected before ingestion of the food items and again at 4 hours, and will be used to determine polyphenol bioavailability.

Study Type

Interventional

Enrollment (Anticipated)

10

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Canada
    • Ontario
      • Guelph, Ontario, Canada, N1G 0B4
        • Nutrasource Diagnostic Inc

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 50 years (Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • healthy, non-smoker on no medication
  • normal glucose tolerance
  • willing to have a catheter inserted in forearm

Exclusion Criteria:

  • abnormal glucose tolerance
  • abnormal BMI
  • on medication for a chronic disorder

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: Randomized
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Glucose Standard
Other: Glycemic response to different varieties of potatoes
the glycemic response top 50g available carbohydrates from 4 potato varieties will be compared to a 50g glucose standard
Other Names:
  • Purple potato
  • Red potato
  • White potato
  • Yellow potaot
Experimental: Potato Variety
Other: Glycemic response to different varieties of potatoes
the glycemic response top 50g available carbohydrates from 4 potato varieties will be compared to a 50g glucose standard
Other Names:
  • Purple potato
  • Red potato
  • White potato
  • Yellow potaot

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Glycemic response
Time Frame: 2 hrs
2 hrs

Secondary Outcome Measures

Outcome Measure
Time Frame
Bioavailability of polyphenols from potatoes
Time Frame: 4 hours
4 hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Guelph Food Research Centre

Collaborators

Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

Investigators

  • Principal Investigator: Dan Ramdath, PhD, Agriculture and Agri-Food Canada
  • Study Director: Maggie Laidlaw, PhD, Nutracource Diagnostics Inc

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2010

Primary Completion (Actual)

February 1, 2010

Study Completion (Actual)

March 1, 2010

Study Registration Dates

First Submitted

January 20, 2010

First Submitted That Met QC Criteria

January 20, 2010

First Posted (Estimate)

January 21, 2010

Study Record Updates

Last Update Posted (Estimate)

January 17, 2011

Last Update Submitted That Met QC Criteria

January 14, 2011

Last Verified

January 1, 2011

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 09-11-004
  • GFRC 09-11-004 (Other Identifier: Canadian Shield)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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