- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01566734
Effect of Cefazolin and Normal Saline Irrigation on Surgical Site Infections (SSIs)
October 12, 2012 updated by: Mohammad E Shahrzad, MD, Hormozgan University of Medical Sciences
Comparison of the Effect of Cefazolin and Normal Saline Irrigation With no Irrigation on the Incidence of Surgical Site Infections
This study conducted to assess the effects of normal saline or cefazolin irrigation on the incidence of SSIs.
Hypothesis:
Normal saline or cefazolin irrigation decreases the incidence of SSIs.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
All pregnant women who underwent cesarean after 6 hours passed their rupture of membrane and attended to Shariati Hospital of Bandarabbass were eligible for our study.
Study Type
Interventional
Enrollment (Actual)
200
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Hormozgan
-
Bandar 'Abbas, Hormozgan, Iran, Islamic Republic of, 79176
- Shariati Hospital
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
No
Genders Eligible for Study
Female
Description
Inclusion Criteria:
- pregnant women
- 6 hours passed their rupture of membrane
- needed to undergo cesarean
Exclusion Criteria:
- allergy to penicillin
- allergy to cefazolin
- history of immunosuppressive drug use
- gestational diabetes mellitus
- preeclampsia
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
No Intervention: Control
|
|
Experimental: Cefazolin
after the surgery and before closing up the patients, 2 grams of cefazolin in 5 cc of distilled water was used to irrigate the patients
|
after the surgery and before closing up the patients, 2 grams of cefazolin in 5 cc of distilled water was used to irrigate the patients
Other Names:
|
Experimental: Normal Saline
after the surgery and before closing up the patients, 150 cc of normal saline was used to irrigate the patients
|
after the surgery and before closing up the patients, 150 cc of normal saline was used to irrigate the patients and in the last group
Other Names:
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
SSI
Time Frame: one week after discharge
|
one week after discharge
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Study Director: Maryam Rahmani, MD, Hormozgan University of Medical Sciences
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
December 1, 2010
Primary Completion (Actual)
December 1, 2011
Study Completion (Actual)
February 1, 2012
Study Registration Dates
First Submitted
March 26, 2012
First Submitted That Met QC Criteria
March 28, 2012
First Posted (Estimate)
March 29, 2012
Study Record Updates
Last Update Posted (Estimate)
October 15, 2012
Last Update Submitted That Met QC Criteria
October 12, 2012
Last Verified
October 1, 2012
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- U1111-1128-4677
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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