Aquatic Aerobic Training, Cardiorespiratory and Metabolic Variables in Coronary Artery Disease

Effects of Aquatic Aerobic Training on Body Composition and Cardiorespiratory and Metabolic Variables in Patients With Coronary Artery Disease

Although approaches to reduce cardiovascular disease, coronary artery disease (CAD) remains the leading cause of mortality in the industrialized world. In order to reduce the deleterious effects of the atherosclerotic process, proposals for non-pharmacological treatment have been used, such as cardiac rehabilitation programs, with emphasis on exercise -based therapy. Traditionally aerobic exercises like biking, walking and jogging are conducted, however, alternative ways such as aquatic exercise training have been proposed, however, the cardiorespiratory adaptations in this population are not well documented in the literature. Thus, the aim of this study was to evaluate the effects of aquatic aerobic training (AAT) on body composition, autonomic modulation of heart rate (HR) and cardiorespiratory and metabolic variables in patients with CAD. This was a longitudinal clinical trial with a sample allocated for convenience, in which twenty-one patients were male, with a diagnosis of CAD, which were divided into control group (CG were studied, n=8), who was only assessed, and training group (TG, n=13). All patients underwent assessment of body composition, heart rate variability (HRV) at rest in the supine posture, and cardiopulmonary exercise testing (CPET), performed before and after the AAT program. The training protocol consisted of three sessions per week on alternate days for 16 weeks, totaling 48 sessions, which had lasted approximately one hour. The exercise intensity was prescribed between 80 and 110% of the first ventilatory threshold (VT1) obtained in CPET. Given that these parameters represent risk markers for cardiovascular events in the population studied, the results suggest that the AAT proposed in this study may be an important therapeutic strategy to be incorporated into cardiac rehabilitation programs.

Study Overview

• Status: Completed
• Conditions: Arteriosclerosis, Coronary
• Intervention / Treatment: Other: Exercise, Aerobic (Water based)

Detailed Description

1. Personal Data recording:

   • History: personal data, lifestyle and food, family history, current and previous history of disease.
   • Physical examination: cardiac and lung auscultation,measurement of heart rate (HR), blood pressure (BP), body weight and height.

2. Assessments:

   All experimental procedures were performed in the morning in order to minimize the influence of circadian cycle. The temperature of the experimental room was maintained between 22 ° C and 24 ° C with relative humidity between 40% and 60%. Patients were familiarized with the experimental protocol, and instructed not to ingest stimulant drinks such as coffee, tea and soft drinks, do not drink alcohol, do not perform strenuous exercise (48 hours before surgery), and to perform a light meal at least four hours before the collections.

   Aiming to verify if the baseline conditions were suitable for the beginning of the experimental procedures, the patients remained 15 minutes of rest in the supine position, and recorded blood pressure (BP) and HR.

   After this, were performed:

   • Analysis of body composition by bioelectrical impedance analysis.
   • Registration of HR and NN intervals (NN) during rest, in the supine and sitting positions.
   • Recording of HR and NN during rest in the supine position, sitting, standing and during respiratory sinus arrhythmia maneuver.
   • Spirometric test and
   • Cardiopulmonary exercise test (CPET). This is a submaximal CPET performed on a treadmill, in order to verify and identify possible changes in hemodynamic, electrocardiographic induced to physical exertion, their aerobic functional capacity as well as to prescribe physical training protocol.

3. Training:

   After this assessment the volunteers were trained by a aerobic water based physical training program for 4 weeks.

4. Second assessment:

Components of the first assessment have been repeated at the end of each month of physical training.

• Study Type: Interventional
• Enrollment (Actual): 21
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Brazil
  • São Paulo
    • Piracicaba, São Paulo, Brazil, 55
      • Universidade Metodista de Piracicaba

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 48 years to 68 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Male

Description

Inclusion Criteria:

• diagnosis by angiography
• sedentaries
• family story of cardiac disease
• obesity

Exclusion Criteria:

• frequent arrhythmias at rest
• triggered by physical effort
• unstable angina
• chronic obstructive pulmonary disease
• insulin-dependent diabet
• renal failure
• sequel of stroke
• uncontrolled hypothyroidism
• water phobia
• skin infections, allergic reactions to chlorine,
• urinary incontinence and
• musculoskeletal and neuromuscular disorders precluding physical tests and training sessions

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Non-Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
No Intervention: Control group; Patients of this group don't performed physical training
Experimental: Exercise, Aerobic (Water based); Patients of this group were submitted to an aerobic water based physical training	Other: Exercise, Aerobic (Water based); Patients of this group were submitted to an aerobic water based physical training

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in autonomic system modulation	Change in autonomic system modulation in assess by comparing the heart rate variability at baseline and after a 16 weeks of aerobic water and land based physical training.	baseline and 16 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in body composition	Change in body composition is assess by comparing the body composition at baseline and after a 16 weeks of aerobic water and land based physical training.	baseline and 16 weeks

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Oxygen uptake	Change in oxygen uptake is assessed by comparing the oxygen uptake at baseline and after a 16 weeks of aerobic water and land based physical training.	16 Weeks

Collaborators and Investigators

• Sponsor: Universidade Metodista de Piracicaba

Publications and helpful links

Helpful Links

• Land versus water exercise in patients with coronary artery disease: effects on body composition, blood lipids, and physical fitness

Study record dates

Study Major Dates

• Study Start: May 1, 2013
• Primary Completion (Actual): October 1, 2013
• Study Completion (Actual): March 1, 2014

Study Registration Dates

• First Submitted: August 5, 2014
• First Submitted That Met QC Criteria: August 5, 2014
• First Posted (Estimate): August 7, 2014

Study Record Updates

• Last Update Posted (Estimate): August 7, 2014
• Last Update Submitted That Met QC Criteria: August 5, 2014
• Last Verified: August 1, 2014

More Information

Terms related to this study

• Keywords: Autonomic Nervous System, Body composition, Oxygen Uptake,; Water Based Physical Training.
• Additional Relevant MeSH Terms: Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Arterial Occlusive Diseases; Coronary Artery Disease; Myocardial Ischemia; Coronary Disease; Arteriosclerosis
• Other Study ID Numbers: 03/14