Hand Grasping Techniques on Eliciting the Grasp Reflex in Patients With Dementia

The Effect of Hand Grasping Techniques on Eliciting the Grasp Reflex in Patients With Dementia or Suspected Frontal Lobe Dysfunction

Sponsors

Lead Sponsor: Rowan University

Source Rowan University
Brief Summary

In this study, the investigators will determine the difference between the two techniques used to elicit the grasp response in patients with frontal lobe dysfunction, primarily in dementia patients versus control patients.

Detailed Description

The goal of this project is to determine the optimal technique to elicit the grasping response in patients with dementia or suspected frontal lobe dysfunction. The proposed study is to perform two techniques to elicit grasp response in patients with dementia or suspected frontal lobe dysfunction and observe the presence or absence of the response and prominence of the response on a proposed rating scale. Future goals will be aimed at aiding clinicians in refining their clinical techniques to be more sensitive for diagnosing frontal lobe dysfunctions.

Overall Status Completed
Start Date July 2016
Completion Date May 23, 2018
Primary Completion Date May 23, 2018
Phase N/A
Study Type Interventional
Primary Outcome
Measure Time Frame
Grasp response six months
Secondary Outcome
Measure Time Frame
Frontal Lobe release- Glabellar Response six months
Frontal lobe release- Palmomental Response six months
Frontal lobe release- Snout Response six months
Enrollment 1
Condition
Intervention

Intervention Type: Other

Intervention Name: palmar grasp without dorsal stimulation

Description: The patient will then be asked to keep the arms at 90 degrees and the researcher will slightly stroke palm and fingers of both hands of the patient simultaneously. After completion of each technique, the presence or absence of the response will be noted. In addition, the prominence of the response on the rating scale will be obtained as explained below. The scaling of the grasp response is as followed: Flexion at the distal interphalangeal joint of the hand Flexion at the proximal interphalangeal joint of the hand Flexion at the metacarpal-phalangeal joint of the hand

Arm Group Label: Standard

Intervention Type: Other

Intervention Name: standard palmar grasp test with dorsal stimulation

Description: The patient will be asked to put their arms at 90 degrees and the researcher will hold one hand at the wrist and dorsum of the palm and lightly stroke the palm and fingers. The patient will be instructed to relax hands and not hold on while doing the grasp and see if the response persists. The same technique will be repeated for the patient's other hand.

Arm Group Label: Standard

Eligibility

Criteria:

Inclusion Criteria:

1. Ability to sign informed consent or have a surrogate present to sign the consent

2. Age 18 or above

3. Patients are diagnosed with dementia, Alzheimer's disease, or frontal lobe dysfunction

4. Medications are to remain stable during the course of the study except for emergency modifications.

Exclusion Criteria:

1. Inability to obtain informed consent from patient or surrogate

2. Unable to follow commands.

3. Physical restrictions (i.e. spasticity of hands/arms, upper extremity amputation)

4. Other comorbidities such as muscular diseases, hepatic encephalopathy, renal failure, down syndrome, NPH, depression, and cerebral palsy.

Gender: All

Minimum Age: 18 Years

Maximum Age: N/A

Healthy Volunteers: No

Overall Official
Last Name Role Affiliation
Donald Barone, DO Principal Investigator Rowan University School of Osteopathic Medicine
Location
Facility: Rowan University School of Osteopathic Medicine
Location Countries

United States

Verification Date

October 2019

Responsible Party

Type: Principal Investigator

Investigator Affiliation: Rowan University

Investigator Full Name: Lauren Fedor

Investigator Title: Program Manager

Keywords
Has Expanded Access No
Condition Browse
Number Of Arms 1
Arm Group

Label: Standard

Type: Other

Description: Prospective, grasp techniques will be compared in each patient from the experimental group using a palmar grasp without dorsal stimulation and a standard palmar grasp test with dorsal stimulation on the same patient as the control group

Acronym GRASP
Patient Data No
Study Design Info

Allocation: N/A

Intervention Model: Single Group Assignment

Primary Purpose: Health Services Research

Masking: None (Open Label)

Source: ClinicalTrials.gov