Surviving a Decade or More After Coronary Revascularization in a Middle Eastern Population (DECADE1+ME)

Evolution of Risk Factors and Revascularization Among >1 Decade Survivors After Coronary Revascularization in the Middle East

The study will look at the cardiovascular risk factors as they arise, as well at the need for further revascularization after at least 10 years of coronary revascularization in Middle Eastern patients.

The PI will overlook the whole process. Dr Ahmad Tamari, the assistant to the PI will asses this whole process of data collection, management and manuscript drafting.

Study Overview

• Status: Completed
• Conditions: Risk Factors AND Repeat Revascularization
• Intervention / Treatment: Other: risk factors and revascularization procedures

Detailed Description

Middle Eastern patients aged 18 years or above presenting to cardiology service at one tertiary care center who had coronary revascularization (stent or coronary bypass surgery, i.e., index procedure) at least 10 years back, will interviewed to determine:

1. Evolution of cardiovascular risk factors in the period from index procedure to time of interview. These risk factors include; hypertension, diabetes, smoking, dyslipidemia and obesity.

2. Need for further arterial revascularization from the index procedure to time of interview.

   These arterial revascularization procedures include A. Coronary: stent and/or bypass surgery B. Carotid endarterectomy. C. peripheral arterial revascularization D. Renal artery stent.

3. Medications used at the time if interview with special emphases on the guideline-recommended medications including antiplatelet agents, beta blockers, statins and renin angiotensin blockers.

• Study Type: Observational
• Enrollment (Actual): 1000

Contacts and Locations

Study Locations

• Jordan
  • Amman, Jordan
    • Istishari Hospital
  • Amman, Jordan
    • Specialty Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: N/A

• Sampling Method: Non-Probability Sample

Study Population

All comers who had undergone coronary stent or bypass surgery 10 years or more prior to interview. These patients will be asked about the appearance of new cardiovascular risk factors during this period and whether they had undergone further operations or procedures to the coronary arteries, carotid arteries, lower limb arteries ir renal arteries.

Description

Inclusion Criteria:

1. Age 18 years or older
2. Coronary stent or bypass 10 years ago or more.
3. Dependable mental status to recall events.

Exclusion Criteria:

1. Non coronary operations
2. Inability to recall evnets

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Risk factors	Appearance of diabetes, hypertension, smoking, dyslipidemia or obesity since index procedure	Since index procedure to time of interview at least 10 years later
Arterial revascularizations	Undergoing further coronary stent or surgery, carotid stent or surgery, lower limbs stent or surgery, and renal artery stent.	Since index procedure to time of interview at least 10 years later

Collaborators and Investigators

• Sponsor: Jordan Collaborating Cardiology Group

Study record dates

Study Major Dates

• Study Start (Actual): June 1, 2018
• Primary Completion (Actual): June 10, 2019
• Study Completion (Actual): June 10, 2019

Study Registration Dates

• First Submitted: April 2, 2018
• First Submitted That Met QC Criteria: April 2, 2018
• First Posted (Actual): April 9, 2018

Study Record Updates

• Last Update Posted (Actual): May 25, 2023
• Last Update Submitted That Met QC Criteria: May 24, 2023
• Last Verified: May 1, 2023

More Information

Terms related to this study

• Other Study ID Numbers: DecadeOrMoreSurvivors01

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No