Meniscus Repair With Simultaneous ACL Reconstruction: Clinical Outcomes，Failure Rates And Subsequent Processing

Our study has explored the causes of failure of meniscus repair and investigated the clinical effects of partial meniscectomy when meniscus repair failed.

Study Overview

• Status: Completed
• Conditions: Meniscus Injury; The ACL Rupture
• Intervention / Treatment: Procedure: Meniscus repair; partial meniscectomy

Detailed Description

Background: Meniscus repair performed during ACL reconstruction may fail and the subsequent treatment includes revision meniscal repair or partial meniscectomy.

Purpose: To retrospectively analyze the clinical outcomes of meniscus repair with simultaneous anterior cruciate ligament (ACL) reconstruction and explore the causes of failure of meniscus repair.

Methods: From May 2013 to July 2018, the clinical data of 165 patients who were treated with meniscus surgery and simultaneous ACL reconstruction by the same doctor, including 69 cases of meniscus repair (repair group) and 96 cases of partial meniscectomy (partial meniscectomy group), were retrospectively analyzed. The 69 patients of the repair group were divided into the nonfailure group (62 cases) and the failure group (7 cases) depending on the repair effect. The average follow-up period was 38 (±10.5) months. Postoperative outcomes of the repair group and the partial meniscectomy group were compared. General conditions and postoperative outcomes of the failure group and the nonfailure group were compared. Seven patients in the failure group who underwent second arthroscopy were followed up for 30 (±17.4) months, and their postoperative outcomes were summarized.

• Study Type: Observational
• Enrollment (Actual): 165

Contacts and Locations

Study Locations

• China
  • Beijing
    • Beijing, Beijing, China, 100191
      • Peking University Third Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 13 years to 60 years (ADULT, CHILD)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

This retrospective case series was conducted to evaluate the clinical outcomes and failure rates of primary meniscus repair with simultaneous ACL reconstruction in patients who were operated by the same physician at our institution.

Description

Inclusion Criteria:

1. patients with intraoperatively confirmed ACL rupture combined with medial, lateral, or medial and lateral meniscal injury;
2. age <60 years
3. no history of previous ipsilateral knee meniscal injury.

Exclusion Criteria:

1. ACL rupture associated with fracture, collateral ligament injury, or complex ligament injury;
2. a history of knee surgery;
3. a significant degree of osteoarthritis.

Study Plan

How is the study designed?

Number of groups / cohorts

3

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
repair group; The first operation in these patients was meniscus repair	Procedure: Meniscus repair; partial meniscectomy; 69 cases of meniscus repair (repair group) and 96 cases of partial meniscectomy (partial meniscectomy group), were retrospectively analyzed. The 69 patients of the repair group were divided into the nonfailure group (62 cases) and the failure group (7 cases) depending on the repair effect.
nonfailure group; These patients had a successful first operation	Procedure: Meniscus repair; partial meniscectomy; 69 cases of meniscus repair (repair group) and 96 cases of partial meniscectomy (partial meniscectomy group), were retrospectively analyzed. The 69 patients of the repair group were divided into the nonfailure group (62 cases) and the failure group (7 cases) depending on the repair effect.
failure group; In these patients, the first meniscus repair operation failed	Procedure: Meniscus repair; partial meniscectomy; 69 cases of meniscus repair (repair group) and 96 cases of partial meniscectomy (partial meniscectomy group), were retrospectively analyzed. The 69 patients of the repair group were divided into the nonfailure group (62 cases) and the failure group (7 cases) depending on the repair effect.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The result of partial meniscus resection	Clinical signs were assessed after the surgery, including swelling of the joint, tenderness at the joint line, locked-in syndrome, and positive McMurray's sign.	Two years after the surgery
International Knee Documentation Committee（IKDC）scores	The minimum is 0, the maximum is 100, and the higher the score, the better the result	Two years after the surgery
Visual analog scale (VAS) scores	The minimum is 0, the maximum is 10, and the higher the score, the worse the result	Two years after the surgery
Lysholm scores	The minimum is 0, the maximum is 100, and the higher the score, the better the result	Two years after the surgery

Collaborators and Investigators

• Sponsor: Peking University Third Hospital

Study record dates

Study Major Dates

• Study Start (ACTUAL): March 16, 2020
• Primary Completion (ACTUAL): April 16, 2020
• Study Completion (ACTUAL): May 16, 2020

Study Registration Dates

• First Submitted: June 25, 2020
• First Submitted That Met QC Criteria: July 1, 2020
• First Posted (ACTUAL): July 2, 2020

Study Record Updates

• Last Update Posted (ACTUAL): July 7, 2020
• Last Update Submitted That Met QC Criteria: July 1, 2020
• Last Verified: July 1, 2020

More Information

Terms related to this study

• Keywords: arthroscopy; meniscus; anterior cruciate ligament reconstruction; failure of repair
• Additional Relevant MeSH Terms: Wounds and Injuries; Rupture
• Other Study ID Numbers: M2020024

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No