Efficacy of Cuminum Cyminum Herbal =Preparation in Inhibition of Plaque and Gingivitis.

February 22, 2021 updated by: DR SURINDER SACHDEVA, Maharishi Markendeswar University (Deemed to be University)

Efficacy of Cuminum Cyminum Herbal Preparation in Inhibition of Plaque and Gingivitis

Present work was to investigate the possible efficacy of 0.2% cuminum cyminum herbal preparation as an antiplaque and antigingivitis agent when compared with chlorhexidine.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

To evaluate and compare the efficacy of 0.2% cuminum cyminum herbal preparation against 0.2% chlorhexidine by various clinical parameters i.e. plaque index, gingival index and sulcus bleeding index.

Study Type

Interventional

Enrollment (Actual)

30

Phase

  • Phase 2
  • Phase 3

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • India
    • Haryana
      • Ambāla, Haryana, India, 133207
        • Department of Periodontology, M.M. College of Dental Sciences and Research.

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

23 years to 30 years (Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • volunteers with minimum 20 natural teeth without restoration.
  • cooperative
  • motivated and committed to participate in the trial period.

Exclusion Criteria:

  • Antibiotic or anti-inflammatory therapy in previous month.
  • Any known allergy/ hypersensitivity to any product used in trial.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: Quadruple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: cuminum cyminum mouthwash
cuminum cyminum mouthwash in chronic gingivitis patients
Drug: Cuminum Cyminum
Cuminum Cyminum mouthwash in chronic gingivitis patients
Other Names:
  • Cuminum Cyminum mouthwash
Active Comparator: herbal mouthwash
herbal mouthwash in chronic gingivitis patients
Drug: herbal Mouthwash
herbal mouthwash in chronic gingivitis patients
Other Names:
  • herbal mouthwash in chronic gingivitis patients

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
PLAQUE INDEX
Time Frame: changes from baseline to 8 days
PLAQUE INDEX: Turesky-Gilmore-Glickman Modification of Quigley Hein 1962
changes from baseline to 8 days
Gingival Index
Time Frame: changes from baseline to 8 days
Gingival Index: Loe H ans Silness 1963
changes from baseline to 8 days
Bleeding on probing
Time Frame: changes from baseline to 8 days
Bleeding on probing: Muhlemann HR and Son 1971
changes from baseline to 8 days

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Maharishi Markendeswar University (Deemed to be University)

Investigators

  • Principal Investigator: surinder sachdeva, M.D.S., professor

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2019

Primary Completion (Actual)

January 15, 2021

Study Completion (Actual)

January 31, 2021

Study Registration Dates

First Submitted

February 9, 2021

First Submitted That Met QC Criteria

February 20, 2021

First Posted (Actual)

February 23, 2021

Study Record Updates

Last Update Posted (Actual)

February 24, 2021

Last Update Submitted That Met QC Criteria

February 22, 2021

Last Verified

February 1, 2021

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • MaharishiMu2012

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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