Impact of Microbe Literacy Initiative on Improved Vaccine Uptake in Peri-urban Slum Areas in Kathmandu, Nepal

Impact of Microbe Literacy Initiative on Improved Vaccine Uptake in Peri-urban Slum Areas in Kathmandu, Nepal: A Community Based Cluster Randomized Controlled Trial

This study is designed to assess the impact of the first introduction of microscope-based health education on people's attitude and practice towards disease prevention in Nepal, measured by vaccine acceptance rate. Such health education has an important role to play in communities where vaccine acceptance is low.

Study Overview

• Status: Not yet recruiting
• Conditions: Vaccine Acceptance
• Intervention / Treatment: Other: Microbe literacy Program in the form of workshop

• Study Type: Interventional
• Enrollment (Anticipated): 1252
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Nepal
  • Bagmati
    • Kathmandu, Bagmati, Nepal, 44600
      • Nepal Health Research Council
      • Contact: Dr. Pradip Gyanwali, MD

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• People aged 18 years or older who are resident of the study target area
• People who stayed at least for 6 months on the area of study
• People who agrees with the procedure of study and follow ups visits
• People who provide consent for their participation will be recruited in the study.

Exclusion Criteria:

• People under 18 years of age will not be enrolled into study due to their limitation of understanding and implementation of the content of workshop given as intervention.
• People who do not wish to participate in the trial
• Those with currently ongoing court hearing and deprive of freedom will not be enrolled for the study.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Health Services Research
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Intervention Arm; Participants allocated in this arm will be approached for a workshop related to microbe literacy. Using a microscope, live demonstration of the biological samples brought by the participants will be carried out by the team of researchers. Participants will be assisted to place biological materials under the microscope, manipulate the slides and discover the profusion of microbial life from the immediate environment. The session will be followed by question and answer round related to concurrent hygiene practices and basic sanitation to prevent infections including vaccines.	Other: Microbe literacy Program in the form of workshop; Two to Three hours of workshop on microbe literacy will be conducted as an intervention. Workshop includes discussion on various common microorganisms causing diseases, their sources, relationship with surroundings and management. Prime focus of the session will be on management via treatments and risk reduction via vaccination.
No Intervention: Control arm; Participants in this arm will be consented for the study and baseline data collection will be made but there will not be any intervention. Data will be collected for baseline as well as post interventional vaccination status among the studied population.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Differential vaccine acceptance rates between intervention and control group	Data will be collected for baseline as well as post intervention after 3 months of workshop. For both the intervention and control group, number of vaccinated among the participants for provided COVID-19 vaccine and Typhoid vaccine will be made. Comparative analysis will be made in both the study groups before and after the intervention program.	Within 3 months of intervention

Collaborators and Investigators

• Sponsor: Nepal Health Research Council
• Collaborators: Microbe Literacy Initiative; Partnership for Sustainable Development Nepal (PSDNepal)

Study record dates

Study Major Dates

• Study Start (Anticipated): July 15, 2022
• Primary Completion (Anticipated): September 30, 2022
• Study Completion (Anticipated): April 17, 2023

Study Registration Dates

• First Submitted: May 12, 2022
• First Submitted That Met QC Criteria: May 12, 2022
• First Posted (Actual): May 18, 2022

Study Record Updates

• Last Update Posted (Actual): July 6, 2022
• Last Update Submitted That Met QC Criteria: July 5, 2022
• Last Verified: July 1, 2022

More Information

Terms related to this study

• Other Study ID Numbers: 39/2022

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No