- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05466136
Mindfulness, Mental Fatigue, Inhibitory Control and Endurance Performance in Athletes
Effects of Mental Fatigue on Inhibitory Control and Endurance Performance in Athletes With Different Levels of Dispositional Mindfulness: An Event-Related Potential Study
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Recent research suggests that mental fatigue by prolonged cognitive tasks would impair neurocognitive functions (e.g., executive functions, brain activity) and sports performance, especially inhibitory control and endurance performance. On the other hand, individuals with higher dispositional mindfulness have been linked to greater athletic performance and cognitive functions. Still, there is little known whether higher dispositional mindfulness counteracts the detrimental effects of mental fatigue on endurance performance and inhibitory control in athletes. Therefore, this study is conducted to investigate whether dispositional mindfulness mediates the effects of mental fatigue on neurocognitive functions and endurance performance in athletes.
The qualified participants will visit the lab on two counterbalanced order occasions to complete either a modified incongruent Stroop task (mental fatigue condition, MF) or a modified congruent Stroop task (control condition, CON) for 30 minutes. Before and after each cognitive task, participants will be measured for their subjective mental fatigue by a visual analog scale (VAS). After each cognitive task, inhibitory control and endurance performance will be evaluated by a Flanker task and a graded exercise test (GXT), respectively. Furthermore, the general and athletic dispositional mindfulness will be measured using the Five Facet Mindfulness Questionnaire (FFMQ) and Athlete Mindfulness Questionnaire (AMQ), respectively.
Specifically, the targeted primary outcomes are neurocognitive functions (i.e., reaction time, accuracy and ERPs in Flanker task) and endurance performance (i.e., VO2max & time to exhaustion in GXT); The secondary outcomes are subjective (i.e., VAS score)/objective (i.e., reaction time, accuracy in Stroop task) mental fatigue, motivation in tasks, mood (i.e., BRUMS-C).
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Contacts and Locations
Study Locations
-
-
-
Taipei, Taiwan, 106
- Department of Physical Education and Sport Sciences, National Taiwan Normal University
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Description
Inclusion Criteria:
- Regular sports training at least 4 hours weekly
- Normal or corrected-to-normal vision
- Right-handed
Exclusion Criteria:
- Physical limitation or injury in lower limbs before and during the study
- Diagnosed or self-reported neurological disorders (e.g., epilepsy)
- Diagnosed or self-reported major psychiatric illness (e.g., major depression, schizophrenia)
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Screening
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Mental fatigue condition
Performing a completed incongruent version of Stroop task for 30min.
|
In mental fatigue condition, the mental fatigue manipulation will use a modified Stroop task with complete incongruent trials, which is wildly used to induce a mentally fatigued state in previous studies.
The Stroop task included four colored words presented in traditional Chinese (i.e., red, green, blue, and yellow), the color of the word will paint inconsistent with the semantic meaning of the word (e.g., red word printed in green).
The task consisted of five 6-minute blocks and 1080 incongruent trials for each block.
The total duration will be 30-min.
|
Experimental: Control condition
Performing a completed congruent version of Stroop task for 30min.
|
Similar to mental fatigue conditions, the modified Stroop task with complete congruent trials will be used, The Stroop task also included four colored words presented in traditional Chinese (i.e., red, green, blue, and yellow), but the color of the word will paint consistent with the semantic meaning of the word (e.g., red word printed in red) in order to set up the match condition of relative less cognitive demanding for participants.
Same with the mental fatigue condition, the task consisted of five 6-minute blocks and 1080 congruent trials for each block.
The total duration will be 30-min.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Inhibitory control: Reaction time
Time Frame: about 1 year
|
Inhibitory control will be evaluated by a Flanker task in terms of reaction time in this study, and the types of trials are the congruent (i.e., > > > > >) and incongruent (i.e., < < > < <).
In the Flanker task, participants will be presented with five arrows and will be instructed to respond as quickly and accurately as possible to the direction where the middle arrow is pointing (i.e., left or right).
|
about 1 year
|
Inhibitory control: Accuracy
Time Frame: about 1 year
|
Inhibitory control will be evaluated by a Flanker task in terms of accuracy in this study, and the types of trials are the congruent (i.e., > > > > >) and incongruent (i.e., < < > < <).
In the Flanker task, participants will be presented with five arrows and will be instructed to respond as quickly and accurately as possible to the direction where the middle arrow is pointing (i.e., left or right).
|
about 1 year
|
Endurance performance: Time to exhaustion
Time Frame: about 1 year
|
The endurance performance in terms of time to exhaustion (TTE) will be assessed by graded exercise test (GXT) with Bruce protocol on treadmill (h/p/cosmos pulsar 3p, Germany).
The initial speed and grade of the GXT will be set at 2.74 km/hr with grade of 10% and increase speed and grade every 3 min until participants are volitionally exhausted.
|
about 1 year
|
Endurance performance: Maximum Oxygen Consumption
Time Frame: about 1 year
|
The maximal oxygen consumption (VO2max) throughout the whole GXT will be recorded by a computerized indirect calorimetry system (SensorMedics Vmax 29C, USA), and until the participants reached volitional exhaustion.
The VO2max in the study will be defined as the highest 30-s average value of VO2 measured during GXT.
|
about 1 year
|
Changes in neuroelectrical activities
Time Frame: about 1 year
|
The neuroelectrical activities during the computerized cognitive tasks (i.e., Stroop task & Flanker task) will be recorded.
The changes in the event-related potential (e.g., P3) will be analyzed.
|
about 1 year
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Subjective mental fatigue
Time Frame: about 1 year
|
Before, after Stroop task, and after Flanker task, changes in subjective mental fatigue will be measured using a visual analog scale for mental fatigue (VAS-MF).
Participants will be asked the following questions "What is your mental fatigue level now?", and participants could indicate how mental fatigue on a scale from 0 (i.e., no mental fatigue at all) to 100 (i.e., completely mentally exhausted).
|
about 1 year
|
Objective mental fatigue: Reaction time in Stroop task
Time Frame: about 1 year
|
During the intervention, the reaction time in both Stroop tasks will be calculated as an index of objective mental fatigue.
|
about 1 year
|
Objective mental fatigue: Accuracy in Stroop task
Time Frame: about 1 year
|
During the intervention, the accuracy in both Stroop tasks will be calculated as an index of objective mental fatigue.
|
about 1 year
|
Rating of perceived exertion
Time Frame: about 1 year
|
The Rating of perceived exertion (RPE) will be measured at beginning and every 2.5-min during the GXT using Borg 6 to 20 scale, until the participant comes to voluntary exhaustion.
|
about 1 year
|
Collaborators and Investigators
Investigators
- Study Director: Yu-Kai Chang, Ph.D, Department of Physical Education and Sport Sciences, National Taiwan Normal University
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- PACNL_JT_MF_Trait
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Mental Fatigue
-
Bakulev Scientific Center of Cardiovascular SurgeryFoundation for the Support of Physical Culture and Sports BECOME A CHAMPION; Autonomous Non-Profit organization of additional education sports school BECOME A CHAMPIONNot yet recruitingEfficacy, Self | Fatigue, Mental | Fatigue; Muscle, Heart | Fatigue; CombatRussian Federation
-
Universita di VeronaUniversity of Southern CaliforniaCompletedDiet, Healthy | Fasting | Fatigue, Mental | Fatigue; Muscle, HeartItaly
-
Supplement Formulators, Inc.Completed
-
PepsiCo Global R&DCompletedMotivation | Mood | Cognitive Performance | Fatigue, Mental | AlertnessUnited States
-
Vedic Lifesciences Pvt. Ltd.CompletedAlert Fatigue, Health PersonnelIndia
-
University GhentCompletedMental Fatigue | Muscle Fatigue | Event-related PotentialsBelgium
-
Lancaster UniversityMedtronic; East Lancashire Hospitals NHS Trust; KARL STORZ Endoscopy-America,... and other collaboratorsCompletedFatigue | Surgery | Fatigue, Mental | Muscle Strain | Training Group, SensitivityUnited Kingdom
-
Eskisehir Osmangazi UniversityRecruitingStress Perception, Psychological Resilience, Compassion FatigueTurkey
-
University of GeorgiaThe Hershey CompanyCompleted
-
Boehringer IngelheimCompletedMental Fatigue | Mental CompetencyUnited Kingdom
Clinical Trials on Mental fatigue condition
-
University GhentCompletedMental Fatigue | Muscle Fatigue | Event-related PotentialsBelgium
-
Vrije Universiteit BrusselCompletedHealthy | Mental FatigueBelgium
-
Vrije Universiteit BrusselCompletedMental Fatigue | Return to Sport | EEG | Brain Activity | Functional PerformanceBelgium
-
Vrije Universiteit BrusselRecruitingHypoxia | Mental Fatigue | Cognition | NIRS | Near Infrared Spectroscopy | Cerebral HeamodynamicsBelgium
-
Vrije Universiteit BrusselCompletedHealthy | Mental Fatigue | Robotics | Industrial WorkBelgium
-
Vrije Universiteit BrusselUnknownThe Electrophysiological Signature of the Mental Fatigue-induced Impairment in Endurance PerformanceMental Fatigue | ElectroencephalographyBelgium
-
Momentum DataOptimum Patient CareCompletedSchizophrenia | Inflammatory Bowel Diseases | Bipolar Disorder | Sleep Disturbance | Suicide, Attempted | Attention Deficit Hyperactivity Disorder | Post-traumatic Stress Disorder | Self Harm | Body Image Disorder | Eating Disorders | Adjustment Disorders | Anxiety Disorder | Depressive Episode | Behavioral Disorder | Psychological Disorder and other conditionsUnited Kingdom
-
University of LiegeRecruiting
-
H. Lee Moffitt Cancer Center and Research InstituteNational Cancer Institute (NCI)CompletedChronic Myelogenous LeukemiaUnited States
-
Centre Hospitalier Universitaire de Saint EtienneRecruiting