Intracranial Arterial Stenosis in Young Patients (ICAS-Young)

April 21, 2025 updated by: Ji Xunming,MD,PhD, Capital Medical University

Intracranial Arterial Stenosis in Young Patients: a Multicenter Longitudinal Cohort Study

The goal of this study is to evaluate the characteristic of intracranial arterial stenosis among young patients.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

500

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • China
      • Beijing, China, 100053
        • Recruiting
        • Xuanwu Hospital, Capital Medical University
        • Contact:
          • Chuanjie Wu, MD
      • Zhengzhou, China
        • Recruiting
        • the First Affiliated Hospital of Zhengzhou University
        • Contact:
          • Yajun Lian
    • An Hui
      • Suzhou, An Hui, China
        • Recruiting
        • Suzhou Municipal Hoapital
        • Contact:
          • Zhengfei Ma, MD
    • Hebei
      • Shijiazhuang, Hebei, China
        • Recruiting
        • The Second Hospital of Hebei Medical University
        • Contact:
          • Fang Xue, MD
        • Principal Investigator:
          • Fang Xue, MD

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Patients with intracranial arterial stenosis

Description

Inclusion Criteria:

  • age < 45 years.
  • stenosis of a major intracranial artery.

Exclusion Criteria:

-

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Symptomatic intracranial arterial stenosis
Other: Routine clinical treatment
Routine clinical treatment is based on the latest international and local guidelines
Asymptomatic intracranial arterial stenosis
Other: Routine clinical treatment
Routine clinical treatment is based on the latest international and local guidelines

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Ischemic stroke in territory of qualifying artery
Time Frame: 1 year
1 year

Secondary Outcome Measures

Outcome Measure
Time Frame
Death
Time Frame: 1 year
1 year
Ischemic stroke in other territory
Time Frame: 1 year
1 year
Any stroke
Time Frame: 1 year
1 year
Stenosis of the intracranial artery
Time Frame: 1 year
1 year

Other Outcome Measures

Outcome Measure
Time Frame
Death
Time Frame: 5 year
5 year
Ischemic stroke in the territory of qualifying artery
Time Frame: 3 year
3 year
Ischemic stroke in other territory
Time Frame: 3 year
3 year
Any stroke
Time Frame: 3 year
3 year
Death
Time Frame: 3 year
3 year
Stenosis of the intracranial artery
Time Frame: 3 year
3 year
Ischemic stroke in the territory of qualifying artery
Time Frame: 5 year
5 year
Ischemic stroke in other territory
Time Frame: 5 year
5 year
Any stroke
Time Frame: 5 year
5 year
Stenosis of the intracranial artery
Time Frame: 5 year
5 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Capital Medical University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 1, 2022

Primary Completion (Estimated)

October 1, 2025

Study Completion (Estimated)

October 1, 2030

Study Registration Dates

First Submitted

April 25, 2023

First Submitted That Met QC Criteria

April 25, 2023

First Posted (Actual)

May 6, 2023

Study Record Updates

Last Update Posted (Actual)

April 24, 2025

Last Update Submitted That Met QC Criteria

April 21, 2025

Last Verified

April 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • ICAS-Young

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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