C-Reactive Protein/Albumin Ratio and Acne Vulgaris

August 21, 2023 updated by: Erdal Pala, Ataturk University

Relationships Between Disease Severity and The C-Reactive Protein/Albumin Ratio and Various Hematological Parameters in Patients With Acne Vulgaris

Objective: Acne vulgaris, an inflammatory disease, was investigated in this study with the claim that C-reactive protein (CRP) / albumin ratio and some hematological parameter ratios have the potential to be used as inflammatory markers to monitor disease severity and prognosis.

Methods: A descriptive cross-sectional study was conducted with two groups of patients aged 18-65 years, 61 patients diagnosed with acne vulgaris and 35 healthy control patients, and routine hemogram and biochemical parameters were compared. The Global Acne Severity Index was used to determine the severity of acne vulgaris.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

96

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
      • Erzurum, Turkey
        • AtaturkU

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Probability Sample

Study Population

Acne vulgaris patients and control healthy individuals

Description

Inclusion Criteria:

  • Acne vulgaris patients diagnosed by a dermatologist
  • Healthy participants without acne
  • 18-40 years of age
  • Voluntary participation

Exclusion Criteria:

  • Aged below18 or above 40 years
  • Not voluntarily participated patents
  • Pregnants, breast milked mothers, emergency situations

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Control group
Healthy participants
Diagnostic test: Biochemical blood analysis
Serum CRP and albumin levels
Acne group
Acne Vulgaris Diagnosed Patients
Diagnostic test: Biochemical blood analysis
Serum CRP and albumin levels

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
CRP/albumin ratio
Time Frame: 3 months
Statistical difference between groups
3 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Usage of CRP/albumin ratio as a Biomarker
Time Frame: 3 months
New detection of CRP/albumin ratio as a new biomarker in the Acne patients
3 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ataturk University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 5, 2022

Primary Completion (Actual)

February 2, 2023

Study Completion (Actual)

May 1, 2023

Study Registration Dates

First Submitted

August 16, 2023

First Submitted That Met QC Criteria

August 21, 2023

First Posted (Actual)

August 22, 2023

Study Record Updates

Last Update Posted (Actual)

August 22, 2023

Last Update Submitted That Met QC Criteria

August 21, 2023

Last Verified

August 1, 2023

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 30.12.2021/567

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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