the Individualized Stepwise Treatment Mode of Adolescent Idiopathic Scoliosis

the Individualized Stepwise Treatment Mode of Adolescent Idiopathic Scoliosis Based on Transformer Learning Algorithm

Based on the risk factors affecting adolescent scoliosis found in the previous social survey, this project adopts the paradigm based on transfer learning and semi-supervised learning, and uses mathematical methods such as multiple learning methods and Transformer image classification algorithms to develop and verify the early warning model and stepped treatment model of adolescent scoliosis, and conducts cost-effect analysis.

Study Overview

• Status: Recruiting
• Conditions: Adolescent Scoliosis
• Intervention / Treatment: Procedure: Conventional treatment; Behavioral: intervention treatment

Detailed Description

This study intends to build a standard system for the prevention and treatment of scoliosis in adolescents, do a good job in school health education and prevention and control work in school, comprehensively strengthen the construction of the prevention and control system of spondylosis, improve the ability of professionals in medical institutions, and give full play to the role of home-school-medical in the prevention and control of abnormal spinal curvature in children Firstly, relying on the investigation report, we independently develop the software platform and physical device for measuring, preventing and correcting scoliosis. Secondly, we use a series of prevention and control advantages to change from passive to active. Based on the Internet and big data technology, we integrate Western medicine data management and monitoring technology to establish the characteristics of the disease General disease information (personal history, family history, solar terms, climate and environment detection indicators, etc.) as one of the health management platform, the management platform set up health archives disease risk early warning health intervention and health promotion education follow-up management system management data quality control review data analysis and visualization 9 modules, respectively set up a management platform patient-side physician side and management background 3 parts through sampling investigation clinical research, break the medical school barriers, to build a personalized step treatment model for adolescent scoliosis.

• Study Type: Interventional
• Enrollment (Estimated): 76
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Xinyun Dr LI, Doctor; Phone Number: 8618069783240; Email: lxyjasmine2010@163.com

Study Locations

• China
  • Zhejiang
    • Hangzhou, Zhejiang, China, 311000
      • Recruiting
      • the Affiliated Zhejiang Provincial People's Hospital to Hangzhou Medical College.
      • Contact: Xinyun Dr LI, Doctor; Phone Number: 8618069783240; Email: lxyjasmine2010@163.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Diagnosis of moderate to mild scoliosis (Cobb angle less than 45°), age 12-16 years, male or female, no psychiatric illness, normal communication, reading and writing

Exclusion Criteria:

• Patients with a clear history of triggers, such as diseases caused by trauma, surgery, etc., cognitive dysfunction, severe heart, liver, kidney and other organ dysfunction, malignant tumors, immune diseases and other malignant diseases

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Triple

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
No Intervention: control; Conventional treatment
Experimental: intervention; Using paradigms based on transfer learning and semi-supervised learning, using multiple learning methods, transformer image classification algorithms and other mathematical methods, an early warning model and stepped treatment model for adolescent scoliosis were developed and verified, and a cost-effectiveness analysis was conducted at the same time.	Procedure: Conventional treatment; Routine medical treatment mode and routine treatment plan, observation and intervention for 4 months.; Behavioral: intervention treatment; Individualized step-by-step treatment model, after screening, the results are imported into the health management platform, and the optimal plan is obtained through data calculation, which is sent to the individual (family) or school, and corresponding treatment is carried out under the guidance of the platform, and observation and intervention 4 months.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of Cobb angles	X-rays were used to check the number of Cobb angles before and 4 months after the intervention to observe the improvement of scoliosis	4 months before the intervention and 4 months after the intervention
Accuracy of new screening modalities	The new screening method "general examination + forward flexion test + scoliosis measuring instrument" was used for examination, and the data results before and 4 months after intervention were compared with the X-ray examination results to verify its accuracy.	4 months before and after the intervention, 4 months after the end of the intervention, and 8 months after the end of the intervention
Hamilton Depression Volume	Depression status was rated using the Hamilton Depression Rating Scale	4 months before and after the intervention, 4 months after the end of the intervention, and 8 months after the end of the intervention

Collaborators and Investigators

• Sponsor: Hangzhou Medical College
• Investigators: Principal Investigator: Xinyun Dr Li, doctor, hangzhou medical colleage

Study record dates

Study Major Dates

• Study Start (Actual): December 20, 2023
• Primary Completion (Estimated): December 1, 2025
• Study Completion (Estimated): December 1, 2026

Study Registration Dates

• First Submitted: March 11, 2024
• First Submitted That Met QC Criteria: March 11, 2024
• First Posted (Actual): March 18, 2024

Study Record Updates

• Last Update Posted (Actual): March 18, 2024
• Last Update Submitted That Met QC Criteria: March 11, 2024
• Last Verified: March 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Musculoskeletal Diseases; Spinal Diseases; Bone Diseases; Spinal Curvatures; Scoliosis
• Other Study ID Numbers: 2024KY920

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No