Effects of Different Concentric and Eccentric Muscle Fatigue Protocols on the Knee Joint Position Sense
July 9, 2024 updated by: Universidade do Porto
Effects of Different Concentric and Eccentric Muscle Fatigue Protocols on the Knee Joint Position Sense: a Randomized Controlled Crossover Trial
The aim of this study was to investigate the effects of different concentric and eccentric muscle fatigue protocols on the knee joint position sense of healthy individuals.
Study Overview
Detailed Description
A randomized controlled crossover trial will be conducted at a biomechanics laboratory with healthy males. All participants will perform with a washout period of 1 week: a control condition (5-minute rest) and 4 local muscle fatigue protocols (concentric of quadriceps; concentric of hamstrings; eccentric of quadriceps; eccentric of hamstrings) in an isokinetic dynamometer at 30º/s. Three maximum voluntary isometric contractions (MVIC) of quadriceps and hamstrings will also be assessed in the beginning of all conditions.
Knee joint position sense will be assessed before and immediately after the fatigue protocols/control condition, through active concentric and eccentric positionings/repositionings, in sitting and prone positions, to a target range of 45º of knee flexion in an isokinetic dynamometer. Surface electromyography electrodes will also be placed on the vastus lateralis and biceps femoris during all procedures.
Study Type
Interventional
Enrollment (Actual)
22
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Porto, Portugal, 4200
- Faculdade de Desporto, Universidade do Porto
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- males aged between 18 and 30 years;
- without current or previous knee pathology or surgery;
- with a low or moderate physical activity level, according to the International Physical Activity Questionnaire;
- normal Body Mass Index (under 24.9 kg/m2), according to the World Health Organization.
Exclusion Criteria:
- those with cardiorespiratory, neurological or vestibular pathologies;
- with positive knee integrity tests (anterior drawer, Lachman's test, posterior drawer; valgus and varus stress testes); and
- those taking any medication that can affect motor control (sedatives, anxiolytics, antibiotics, analgesics, NSAIDs or myorelaxants).
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Health Services Research
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
No Intervention: Control Condition
5-minute rest period.
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Active Comparator: Quadriceps_Concentric
40 consecutive maximal concentric contractions of quadriceps at 30º/s
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Four experimental conditions consisting of different local muscle fatigue protocols performed in the isokinetic dynamometer in random order, with at least one week of interval between them.
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Active Comparator: Quadriceps_Eccentric
40 consecutive maximal eccentric contractions of quadriceps at 30°/s
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Four experimental conditions consisting of different local muscle fatigue protocols performed in the isokinetic dynamometer in random order, with at least one week of interval between them.
|
|
Active Comparator: Hamstrings_Concentric
30 consecutive maximal concentric contractions of hamstrings at 30º/s
|
Four experimental conditions consisting of different local muscle fatigue protocols performed in the isokinetic dynamometer in random order, with at least one week of interval between them.
|
|
Active Comparator: Hamstrings_Eccentric
30 consecutive maximal eccentric contractions of the hamstrings at 30º/s
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Four experimental conditions consisting of different local muscle fatigue protocols performed in the isokinetic dynamometer in random order, with at least one week of interval between them.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Absolute angular error
Time Frame: Change from Baseline (Before) to Immediately after interventions or control (After)
|
The absolute value of the difference between the target range and the achieved range
|
Change from Baseline (Before) to Immediately after interventions or control (After)
|
|
Relative angular error
Time Frame: Change from Baseline (Before) to Immediately after interventions or control (After)
|
The arithmetic difference between the target range and the range achieved
|
Change from Baseline (Before) to Immediately after interventions or control (After)
|
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Variable angular error
Time Frame: Change from Baseline (Before) to Immediately after interventions or control (After)
|
The standard deviation of the 3 repositionings
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Change from Baseline (Before) to Immediately after interventions or control (After)
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
November 2, 2023
Primary Completion (Actual)
May 5, 2024
Study Completion (Actual)
May 15, 2024
Study Registration Dates
First Submitted
March 19, 2024
First Submitted That Met QC Criteria
March 19, 2024
First Posted (Actual)
March 26, 2024
Study Record Updates
Last Update Posted (Actual)
July 11, 2024
Last Update Submitted That Met QC Criteria
July 9, 2024
Last Verified
March 1, 2024
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- JSA_Fatigue_FADEUP
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
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