To Investigate the Effectiveness of Topical Glycerine Sulphate, Hirudoid Cream and Nil Application in Treating Peripheral Cannula Related Phlebitis

Effectiveness of Topical Glycerine Sulphate Paste, Hirudoid Cream and Nil Application on Superficial Phlebitis

Sponsors

Lead sponsor: Tan Tock Seng Hospital

Source Tan Tock Seng Hospital
Brief Summary

The aim of the interventional study is to compare the different treatment modalities in reducing erythema size and rate of resolving phlebitis.

Overall Status Completed
Start Date November 2009
Completion Date February 2010
Primary Completion Date February 2010
Phase N/A
Study Type Interventional
Primary Outcome
Measure Time Frame
Erythema size 5 days
Secondary Outcome
Measure Time Frame
Time to resolve redness 5 days
Enrollment 147
Condition
Intervention

Intervention type: Drug

Intervention name: Glycerine Magnesium sulphate paste

Description: Dosage to apply adheres to the manufacturer's recommendation. Sufficient amount should cover the erythema size. Dose frequency is 12 hourly.

Arm group label: Glycerine Magnesium Sulphate paste

Intervention type: Drug

Intervention name: Mucopolysaccharide polysulphate

Description: Dosage to apply adheres to the manufacturer's recommendation. Sufficient amount should cover the erythema size. Dose frequency is 12 hourly.

Arm group label: Hirudoid cream

Intervention type: Other

Intervention name: No application

Description: No application

Arm group label: No application

Eligibility

Criteria:

Inclusion Criteria:

- Patients admitted to the study institution between Dec 2009 and Feb 2010 and observed to develop redness associated with peripheral infusion cannula.

Exclusion Criteria:

- Thrombosis, poor skin condition, and pus seen at the previous puncture.

Gender: All

Minimum age: 21 Years

Maximum age: N/A

Healthy volunteers: No

Overall Official
Last Name Role Affiliation
Isabel Ng, MSc Epidemiology Principal Investigator Tan Tock Seng Hospital
Location
facility Tan Tock Seng Hospital
Location Countries

Singapore

Verification Date

October 2010

Responsible Party

Name title: Isabel Ng Hui Leng

Organization: Tan Tock Seng Hospital

Keywords
Has Expanded Access No
Condition Browse
Number Of Arms 3
Arm Group

Arm group label: Glycerine Magnesium Sulphate paste

Arm group type: Active Comparator

Arm group label: Hirudoid cream

Arm group type: Active Comparator

Description: Topical Mucopolysaccharide polysulphate

Arm group label: No application

Arm group type: Experimental

Description: Patient will not receive any topical application to apply on the phlebitis site. The outcome assessor will monitor regularly at pre-determined schedule as patients in other active arms.

Study Design Info

Allocation: Randomized

Intervention model: Parallel Assignment

Primary purpose: Treatment

Masking: None (Open Label)

Source: ClinicalTrials.gov