Co-induction Technique Compared to Standard Inhalational and Intravenous Induction Techniques
A Novel Co-induction Technique Compared to Standard Inhalational and Intravenous Induction Techniques: a Prospective Randomized Control Study
연구 개요
상태
상세 설명
Co-induction technique refers to the use of a combination of medications to reach the desired therapeutic target. This technique is considered an approach that can be of a great benefit to patients with chronic medical illnesses and those who have moderate to high risk for general anaesthesia.
In the present study, the investigators examined the safety of a novel co-induction approach that relied on a simple timing and dosing alterations to the classical approaches of inhalational sevoflurane and propofol induction. The significance of this study is to find a reliable safe alternative method of induction that can provide optimal parameters,when compared to the classical methods of induction. The investigators evaluated the time needed for laryngeal mask airway (LMA) insertion, number of LMA insertion trials, succession of LMA insertion, adverse events related to the airway, respiratory and cardiovascular systems, haemodynamic stability and satisfaction scores of enrolled patients.
연구 유형
등록 (실제)
단계
- 해당 없음
연락처 및 위치
연구 장소
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Amman, 요르단, 11942
- Jordan University Hospital
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참여기준
자격 기준
공부할 수 있는 나이
건강한 자원 봉사자를 받아들입니다
연구 대상 성별
설명
Inclusion Criteria:
- patients with Age ≥ 65 years.
- American Society of Anaesthesiologists' (ASA) score II or III.
- minimally invasive endoscopic urological procedures.
Exclusion Criteria:
- patient refusal.
- Age < 65 years.
- family history of malignant hyperthermia.
- prolonged surgery that needed intubation.
- body mass index (BMI) > 35 kg/m2.
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 방지
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
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실험적: Group P
Patient received a dose of 1.5 mg/kg of Propofol slowly over 2 minutes for induction.
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Patients were given 1.5 mcg/Kg of fentanyl intravenously.
two minutes after the fentanyl dose, a dose of 1.5 mg/kg of propofol slowly over 2 minutes.
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실험적: Group S
Patient received 8% sevoflurane through sealed plastic facemask at 8 L/min flow of oxygen.
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Patients were given 1.5 mcg/Kg of fentanyl intravenously.
two minutes after the fentanyl dose, patient received 8% inhalational sevoflurane through sealed plastic face mask at 8 L/min flow of oxygen.
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실험적: Group C
Patient received 4% sevoflurane through sealed plastic facemask at 8 L/min flow of oxygen for 2 minutes, followed by a dose of 0.75 mg/kg of propofol given slowly.
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Patients were given 1.5 mcg/Kg of fentanyl intravenously.
two minutes after the fentanyl dose, patient received 4% sevoflurane through sealed plastic face mask at 8 L/min flow of oxygen for 2 minutes, followed by a dose of 0.75 mg/kg of propofol given slowly.
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Intraoperative respiratory adverse events
기간: 8 months
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The investigators recorded the occurrence of transient apnea intraoperatively, in addition to laryngeal spasm, coughing, gagging and increased salivation.
The study chart included the documentation these common adverse events, the timing of occurrence, and the intervention required to manage these events.
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8 months
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2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Time for successful laryngeal mask airway insertion
기간: 8 months
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The investigators assessed the time needed for LMA insertion.
The timer was started upon giving the fentanyl, recording the time till successful insertion of laryngeal mask airway.
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8 months
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Blood pressure stability
기간: 8 months
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The investigators recorded patients' blood pressure readings throughout the induction procedure.
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8 months
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Heart rate stability
기간: 8 months
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The investigators recorded patients' heart rate throughout the induction procedure.
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8 months
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Changes in oxygen saturation
기간: 8 months
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The investigators recorded patients' oxygen saturation throughout the induction procedure.
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8 months
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공동 작업자 및 조사자
연구 기록 날짜
연구 주요 날짜
연구 시작 (실제)
기본 완료 (실제)
연구 완료 (실제)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 연구와 관련된 용어
추가 관련 MeSH 약관
기타 연구 ID 번호
- 10/2016/4597
개별 참가자 데이터(IPD) 계획
개별 참가자 데이터(IPD)를 공유할 계획입니까?
약물 및 장치 정보, 연구 문서
미국 FDA 규제 의약품 연구
미국 FDA 규제 기기 제품 연구
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