Retinal Function in Diabetic Patients Without Retinopathy (NEURODIAB)

For diabetic patients :

age between 20 and 55 type 1 or type 2 diabetes mellitus diabetes duration of more than 5 years no diabetic retinopathy on fundus examination or fundus photographs

For control subjects :

sex and age matching with the diabetic patients no diabetes, no familial or personal history of elevated blood sugar

Inclusion Criteria:

• For diabetic patients :

  • age between 20 and 55
  • type 1 or type 2 diabetes mellitus
  • diabetes duration of more than 5 years
  • no diabetic retinopathy on fundus examination or fundus photographs

• For control subjects :

  • sex and age matching with the diabetic patients
  • no diabetes, no familial or personal history of elevated blood sugar

Exclusion Criteria:

*For both diabetic patients and control subjects :

• presence of cataract or history of cataract surgery
• intraocular pressure of more than 21 mmHg
• abnormal score on the Ishihara test
• other ocular disease
• ametropia more than 3 diopters, anisometropia more than 1 diopter, astigmatism more than 1 diopter
• systemic hypertension (defined as systolic blood pressure > 140 mmHg, diastolic blood pressure > 90 mmHg)
• treatment with vasoactive drugs
• tobacco consumption of more than 20 cigarettes a day