- ICH GCP
- US Clinical Trials Registry
- Klinisk utprøving NCT03798405
Reactive vs. Proactive Pain Control in IBD (PAIN-Sparing)
Reactive vs. Proactive Pain Control in Hospitalized Patients With Inflammatory Bowel Disease
The investigators will compare two physician behaviors for managing pain in patients with IBD: proactive vs. reactive. Both the proactive and reactive behavior/strategies are standard of care at the institution in which the study will be performed. The PROACTIVE strategy is an IBD-specific analgesic orderset (built into our EMR and approved by the institution's Pharmacy and Therapeutics committee), the REACTIVE strategy is a traditional "reactive" analgesic prescribing (prescribing medications only when patients have pain). The PROACTIVE IBD-specific analgesic orderset consists of medications which have evidence for use in IBD-related pain. This orderset is an educational guide, it does not force any order. The reactive prescribing habits could contain an array of pain medications depending on what the provider wants to prescribe.
Aims:
Aim 1: To assess whether there is a difference in pain scores or functional activity among hospitalized patients with IBD between reactive vs proactive physician behaviors.
Aim 2: To assess whether there is a difference in inpatient opioid-prescribing between reactive vs proactive physician behaviors.
Aim 3: To assess whether there is a difference in health care utilization, including length-of-stay and 30-day readmission, between reactive vs proactive physician behaviors.
Studieoversikt
Status
Intervensjon / Behandling
Detaljert beskrivelse
Studietype
Registrering (Faktiske)
Fase
- Ikke aktuelt
Kontakter og plasseringer
Studiesteder
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California
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Los Angeles, California, Forente stater, 90048
- Cedars-Sinai Medical Center
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Deltakelseskriterier
Kvalifikasjonskriterier
Alder som er kvalifisert for studier
Tar imot friske frivillige
Kjønn som er kvalifisert for studier
Beskrivelse
Inclusion Criteria:
- Adults with confirmed IBD diagnosis
- Admitted for primary IBD-related sign or symptom
Exclusion Criteria:
- Admitted for primary non-IBD complaint
- Surgery in the last 30 days
- Alternative (non-IBD) GI diagnosis determined
- Age <18
- Pregnancy
Studieplan
Hvordan er studiet utformet?
Designdetaljer
- Primært formål: Helsetjenesteforskning
- Tildeling: Randomisert
- Intervensjonsmodell: Parallell tildeling
- Masking: Dobbelt
Våpen og intervensjoner
Deltakergruppe / Arm |
Intervensjon / Behandling |
---|---|
Eksperimentell: Proactive
Proactive Analgesic Inpatient Narcotic-Sparing: Pain management in patients in the proactive physician-behavior group will be based on the IBD Pain orderset in our EMR. This orderset is already in use and standard-of-care at Cedars. The orderset uses pain medications, which have evidence for use in IBD. The orderset is simply a guide to clinicians and does not force any doctor or patient to be in a "protocol". |
Medications suggested to the physician with enhanced ease of ordering.
Andre navn:
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Ingen inngripen: Reactive (Control Group)
Pain management in patients in the reactive group (control group) will follow traditional prescribing habits.
As different providers vary in the way they treat pain, analgesic medication prescribing in the control group will be inherently variable in nature.
The control group does not constitute a lack of treatment or placebo; rather, pain management in the control group will not be proactive as in the intervention group.
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Hva måler studien?
Primære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
---|---|---|
Patient-Reported Pain Scores
Tidsramme: Difference in the average daily pain score from the first to the last day of hospitalization, typically 7 days.
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Visual Analog Pain Numeric Rating Scale (Scale range 0 (no pain) to 10 (severe pain))
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Difference in the average daily pain score from the first to the last day of hospitalization, typically 7 days.
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Sekundære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
---|---|---|
Healthcare Utilization
Tidsramme: From hospital admission until hospital discharge, typically 7 days.
|
Hospital length of stay (in days)
|
From hospital admission until hospital discharge, typically 7 days.
|
Functional Activity
Tidsramme: From hospital admission until hospital discharge, typically 7 days.
|
FitBit activity (number of steps per day)
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From hospital admission until hospital discharge, typically 7 days.
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Opioid-Consumption
Tidsramme: From hospital admission until hospital discharge, typically 7 days.
|
Milligram morphine-equivalents consumed per day
|
From hospital admission until hospital discharge, typically 7 days.
|
Samarbeidspartnere og etterforskere
Sponsor
Etterforskere
- Studieleder: Sameer K Berry, MD, MBA, Cedars-Sinai Medical Center
Studierekorddatoer
Studer hoveddatoer
Studiestart (Faktiske)
Primær fullføring (Faktiske)
Studiet fullført (Faktiske)
Datoer for studieregistrering
Først innsendt
Først innsendt som oppfylte QC-kriteriene
Først lagt ut (Faktiske)
Oppdateringer av studieposter
Sist oppdatering lagt ut (Faktiske)
Siste oppdatering sendt inn som oppfylte QC-kriteriene
Sist bekreftet
Mer informasjon
Begreper knyttet til denne studien
Nøkkelord
Ytterligere relevante MeSH-vilkår
Andre studie-ID-numre
- Pro00050742
Plan for individuelle deltakerdata (IPD)
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