Vitamin D Supplementation and CD4 Count in HIV-Infected Children

Inclusion Criteria:

• HIV-infected children as defined by ≥ 2 positive HIV DNA PCRs and/or HIV cultures of blood for children less than 18 months of age, or by positive screening and confirmatory serologic testing in those older than 18 months of age
• Stable HIV disease, defined by the absence of change in HIV clinical or immunologic category during the preceding 6 month period, prior to commencing the study
• Age 3 years through 18 years
• Voluntary informed consent

Exclusion Criteria:

• Any antiretroviral medication change in the 6 months prior to the study, or any anticipated antiretroviral medication change during the duration of the study
• Active participation in another treatment trial
• Serum calcium < 2mmol/L at baseline