- ICH GCP
- Amerikanska kliniska prövningsregistret
- Klinisk prövning NCT05375422
Effects of SARAH Protocol in Women With Rheumatoid Arthritis
11 maj 2022 uppdaterad av: Samira Tatiyama Miyamoto, PhD, Federal University of Espirito Santo
Effects of the Strengthening and Stretching Protocol for Rheumatoid Arthritis in the Hands (SARAH) on Hand Function in Women With Rheumatoid Arthritis
The aim of this randomized controlled trial is to analyze the effect of the SARAH protocol, which is a set of exercises with components of muscle strengthening, range of motion gain and home exercises, combined with an educational intervention, on hand function in women with rheumatoid arthritis (RA).
Studieöversikt
Status
Rekrytering
Betingelser
Intervention / Behandling
Detaljerad beskrivning
The volunteers will be randomized between groups: control group (n=30), which will receive usual guidelines and the SARAH group (n=30), which will perform the SARAH protocol exercises (brazilian portuguese version) along with the usual guidelines.
To participate in the research, patients must be diagnosed with RA using disease-modifying antirheumatic medication for at least 3 months, and age equal to or older to 18 years.
Participants with incomplete elementary school and score <24 on the Mini-Mental State Examination Questionnaire (MMSE) will be excluded from the study.
The participants will be evaluated before and after the intervention regarding the variables: hand function (Michigan Hand Outcomes Questionnaire), pain (Brief Pain Inventory), handgrip strength (Jamar® manual dynamometer), quality of life (Euro Quality of Life Instrument-5D), functional capacity (Health Assessment Questionnaire), RA disease activity (DAS28).
The SARAH group will receive an exercise book containing 7 mobility exercises and 4 strength exercises that are performed using elastic materials that provide progressive degrees of resistance to movement.
Patients will be guided in person by a trained professional, so that they are carried out without their presence, in the home environment, daily and monitored at periodically scheduled meetings.
A total of 4 face-to-face meetings will be held during the 3-month follow-up.
The SARAH group and the control group will receive information related to joint protection, use of splints, assistive devices and other general advice, as needed, will receive some booklets to reinforce the guidelines.
The program will last 12 weeks, with 4 face-to-face meetings lasting 40 minutes and monitored in periodically scheduled meetings.
Studietyp
Interventionell
Inskrivning (Förväntat)
60
Fas
- Inte tillämpbar
Kontakter och platser
Det här avsnittet innehåller kontaktuppgifter för dem som genomför studien och information om var denna studie genomförs.
Studiekontakt
- Namn: Samira T Miyamoto, PhD
- Telefonnummer: +55 27 997606447
- E-post: sa.miyamoto@hotmail.com
Studera Kontakt Backup
- Namn: Ludmila Forechi, PhD
- Telefonnummer: +55 21 998132300
- E-post: ludimilaforechi@yahoo.com.br
Studieorter
-
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ES
-
Vitória, ES, Brasilien, 29050-780
- Rekrytering
- Samira Tatiyama Miyamoto, PhD
-
Kontakt:
- Samira T Miyamoto, PhD
- Telefonnummer: +55 27 997606447
- E-post: sa.miyamoto@hotmail.com
-
-
Deltagandekriterier
Forskare letar efter personer som passar en viss beskrivning, så kallade behörighetskriterier. Några exempel på dessa kriterier är en persons allmänna hälsotillstånd eller tidigare behandlingar.
Urvalskriterier
Åldrar som är berättigade till studier
18 år och äldre (Vuxen, Äldre vuxen)
Tar emot friska volontärer
Nej
Kön som är behöriga för studier
Kvinna
Beskrivning
Inclusion Criteria:
- patients must be diagnosed with RA
- using disease-modifying antirheumatic medication for at least 3 months
- over 18 years old
Exclusion Criteria:
- incomplete elementary school and score <24 on the Mini-Mental State Examination Questionnaire (MMSE)
- diagnosis of another associated autoimmune disease
- having undergone previous surgical procedures on the hands
- having suffered a fracture in the joints of the upper limbs in the last six months
- being a patient on the waiting list for orthopedic surgery of the upper limb
- being pregnant.
Studieplan
Det här avsnittet ger detaljer om studieplanen, inklusive hur studien är utformad och vad studien mäter.
Hur är studien utformad?
Designdetaljer
- Primärt syfte: Behandling
- Tilldelning: Randomiserad
- Interventionsmodell: Parallellt uppdrag
- Maskning: Trippel
Vapen och interventioner
Deltagargrupp / Arm |
Intervention / Behandling |
---|---|
Experimentell: SARAH group
The SARAH group will receive an exercise book containing 7 mobility exercises and 4 strength exercises that are performed using elastic materials that provide progressive degrees of resistance to movement.
Patients will be guided in person by a trained professional, so that they are carried out without their presence, in the home environment, daily and monitored at periodically scheduled meetings.
A total of 4 face-to-face meetings will be held during the 3-month follow-up.
The SARAH group and the control group will receive information related to joint protection, use of splints, assistive devices and other general advice, as needed, will receive some booklets to reinforce the guidelines.
The program will last 12 weeks, with 4 face-to-face meetings lasting 40 minutes and monitored in periodically scheduled meetings.
|
Set of exercises with components of muscle strengthening, range of motion gain and home exercises.
Information related to joint protection, use of splints, assistive devices and other general advice, as needed.
|
Aktiv komparator: Control group
Control group will receive information related to joint protection, use of splints, assistive devices and other general advice, as needed, will receive some booklets to reinforce the guidelines. After 12 weeks, the control group will also be invited to perform the SARAH protocol exercises. |
Information related to joint protection, use of splints, assistive devices and other general advice, as needed.
|
Vad mäter studien?
Primära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
---|---|---|
Hand function
Tidsram: 3 months
|
Michigan Hand Outcomes Questionnaire.
A total of 37 items assess six domains: general hand function, activities of daily living, work performance, pain, aesthetics, and patient satisfaction with hand function.
The participant must score each item using Likert-type scales ranging from 1 to 5.
|
3 months
|
Sekundära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
---|---|---|
Pain inventory
Tidsram: 3 months
|
Brief Pain Inventory.
It classifies pain as mild when scored from 1 to 4, moderate when scored from 5 to 7, and severe when the participant selects values from 8 to 10 points.
|
3 months
|
Hand grip strength
Tidsram: 3 months
|
Hand dynamometer.
The participant should press the dynamometer with maximum force for 3 seconds and rest for 60 seconds.
All values must be recorded for later calculation of the average of three attempts.
|
3 months
|
Healthy related quality of life
Tidsram: 3 months
|
Euro Quality of Life Instrument-5D (EQ-5D).
The questionnaire consists of questions about health and disease states, such as: mobility, personal care, usual activities, pain/discomfort, anxiety/depression, and each of these has three associated levels of severity, corresponding to no problems (level 1).
), some problems (level 2) and extreme problems (level 3) experienced or felt by the individual.
|
3 months
|
Functional capacity
Tidsram: 3 months
|
Health Assesment Questionnaire (HAQ).
Eight categories with scores from 0 (no problem) to 3 (unable to do) per category.
The score for each category appears at the highest number of any of its items, and the final HAQ score is the average of the scores for the eight categories.
|
3 months
|
Disease activity
Tidsram: 3 months
|
Disease Activity Score (DAS-28).
The DAS-28 score can be interpreted on a categorical scale: it is indicative of disease remission values <2.6, light activity when it has a result between 2.6 and 3.2, moderate activity when values >3.2 to 5, 1 and high disease activity when the result is greater than 5.1.
|
3 months
|
Samarbetspartners och utredare
Det är här du hittar personer och organisationer som är involverade i denna studie.
Studieavstämningsdatum
Dessa datum spårar framstegen för inlämningar av studieposter och sammanfattande resultat till ClinicalTrials.gov. Studieposter och rapporterade resultat granskas av National Library of Medicine (NLM) för att säkerställa att de uppfyller specifika kvalitetskontrollstandarder innan de publiceras på den offentliga webbplatsen.
Studera stora datum
Studiestart (Faktisk)
7 februari 2022
Primärt slutförande (Faktisk)
7 maj 2022
Avslutad studie (Förväntat)
7 februari 2024
Studieregistreringsdatum
Först inskickad
11 maj 2022
Först inskickad som uppfyllde QC-kriterierna
11 maj 2022
Första postat (Faktisk)
16 maj 2022
Uppdateringar av studier
Senaste uppdatering publicerad (Faktisk)
16 maj 2022
Senaste inskickade uppdateringen som uppfyllde QC-kriterierna
11 maj 2022
Senast verifierad
1 maj 2022
Mer information
Termer relaterade till denna studie
Nyckelord
Ytterligare relevanta MeSH-villkor
Andra studie-ID-nummer
- FUEspiritoSanto03
Plan för individuella deltagardata (IPD)
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NEJ
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Kliniska prövningar på SARAH
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