Computer-Assisted Adherence Program for Patients Taking Anti-HIV Drugs
A Computer-Based HIV Medication Adherence Intervention
研究概览
详细说明
Highly active antiretroviral therapy (HAART) for HIV produces dramatic reductions in morbidity and mortality for many patients who maintain a high level of adherence to their medications. However, 20% to 33% of HIV infected patients will miss at least one of their medication doses over a one to three day period. Patient self-report is the most practical method for assessing adherence, but it may produce unreliable and invalid results unless optimally performed. A computer-assisted, self-administered adherence program could improve HIV infected patients' adherence behaviors by accurately and efficiently assessing their medication adherence, delivering an adherence intervention to patients, and producing adherence reports for providers. By providing a neutral and seemingly private interview, computer programs may increase patient disclosure of non-adherence. This study will evaluate the efficacy of a computer-assisted, self-administered adherence program in reducing regimen misunderstandings and enhancing patient adherence.
Participants in this study will be recruited from within the Positive Health Program at San Francisco General Hospital. Patients will be randomly assigned to a Control or Intervention Group. Control Group participants will complete an audio computer-assisted self-interview (A-CASI) assessing their understanding of their medication regimen and adherence. Intervention Group participants will complete the adherence A-CASI and will receive a brief computer-delivered intervention consisting of a graphical depiction of their correct regimen and strategies for improving adherence. Study investigators will forward a computer-generated adherence report, which summarizes their adherence and suggests appropriate interventions, to the Intervention Group's health care providers. All participants will be assessed at least three times over a 6-month period: study entry, Month 3, and Month 6.
研究类型
注册
阶段
- 不适用
联系人和位置
学习地点
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California
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San Francisco、California、美国、94110
- San Francisco General Hospital
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria
- Receiving HIV care at San Francisco General Hospital's Positive Health Program
- Three or more antiretroviral medications
- HIV-1 viral load > 500 copies/ml
- At least one previous salvage regimen
- Ability to read English at 8th grade level
Exclusion Criteria
- Visual impairments that prevent patient from reading text on a computer screen
- Obvious cognitive impairment
学习计划
研究是如何设计的?
设计细节
- 主要用途:教育/咨询/培训
- 分配:随机化
- 介入模型:阶乘赋值
- 屏蔽:无(打开标签)
合作者和调查者
调查人员
- 学习椅:Frederick M. Hecht, MD、San Francisco General Hospital
- 研究主任:Amy B. Bronstone, PhD、West Portal Software Corporation
- 首席研究员:Roger Hofmann, BS、West Portal Software Corporation
研究记录日期
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.
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