Evaluation of Conventional Antibiotic Prophylaxis During a Change of Hip or Knee Infected at a Time
Evaluation of the Effect of a Conventional Antibiotic Prophylaxis on the Positivity of Intraoperative Bacteriological Samples During a Change of Hip or Knee Infected at a Time
Infection is a serious complications after undergoing total hip replacement. It occurs in about 1% of cases. The optimal treatment of these infections is discussed. The team validated by international publications change strategy of the infected prosthesis at a time.
Antibiotic prophylaxis has significantly reduced the infection intraoperative contamination in orthopedic surgery rates. It must be conventionally administered before the surgical incision. In response to infection, it is typically recommended to start this antibiotic after the completion of the deep bacteriological samples, so as not to negate the risk of these samples by the prior administration of antibiotics. This attitude, however, is not formally validated by the scientific literature. In contrast, two recent publications challenge this practice, and suggest the use of a conventional antibiotic prophylaxis even in septic interventions. Our multidisciplinary team opted for a few months for this new strategy. We wish to evaluate the influence of this new approach results in the treatment of infection in total hip or knee.
研究概览
研究类型
注册 (预期的)
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- patients operated in service between January 2012 and July 2013 for treatment of an infection of total hip or knee.
Exclusion Criteria:
- patients operated in service before January 2012 and after July 2013 for treatment of an infection of total hip or knee.
学习计划
研究是如何设计的?
设计细节
- 观测模型:队列
- 时间观点:追溯
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
concordance of pre-and intraoperative bacteriological documentation
大体时间:preoperative; intraoperative
|
concordance of pre-and intraoperative bacteriological documentation (division into 3 classes: complete, partial, no - Chi-square test
|
preoperative; intraoperative
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
---|---|---|
rates to relapse of the initial infection or a new infection
大体时间:preoperative; intraoperative
|
rates to relapse of the initial infection or a new infection (survival curves according to Kaplan-Meier with log-rank test)
|
preoperative; intraoperative
|
合作者和调查者
研究记录日期
研究主要日期
学习开始
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他研究编号
- 004-14
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