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Social Network Approach for Increasing Testing Coverage Among Men Who Have Sex With Men

2021年12月19日 更新者:Tsz Ho Kwan、Chinese University of Hong Kong
HIV testing is essential in shortening the time to identify a new infection, the first 90 of the UNAIDS 90-90-90 targets. However, over one-third of the men who have sex with men (MSM) had never been tested for HIV; even if they did, one-fifth had their tests done more than a year ago. Assortative mixing pattern observed in the HIV-positive MSM group shaped the transmission dynamics and could be leveraged for intervention. Barriers to access HIV testing services could, on the other hand, be hurdled by self-tests. A network approach for intervention could therefore be promising in delivering effective HIV self-tests. To experiment with such an approach, a 2-phase study was conceptualised incorporating actual network-based referred HIV self-tests and an agent-based simulation evaluating its impact. Sixty-four MSM would be recruited as seeds for promoting HIV self-tests within their network and those being referred could refer their friends for the same after passing online training. To facilitate the process, an online platform would be developed offering information, collecting informed consent, requesting HIV self-test kits, returning results, performing online training, and referring peers. Participants could opt to receive self-tests by delivery or to conduct it on-site with staff assistance. A hotline with video conferencing support would be maintained to assist those who self-test at home. They could also choose between blood and oral fluid tests. Two user interfaces, namely gamification and neumorphism, would be randomly assigned. Primary outcomes to measure are number and proportion of MSM who had never or not tested within 12 months and the associating factors, and usability of the two user interfaces. Data collected in the empirical study would be used for parameterising the agent-based simulation to evaluate the impact of the approach in increasing testing coverage and shortening time to diagnosis. Its economic assessment would also be performed to cost each new infection to be identified. The approach could be feasible and effective to be adopted for future broader implementation for peer-led HIV self-test kit or HIV prevention message distribution.

研究概览

研究类型

观察性的

注册 (实际的)

463

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

      • Sha Tin、香港
        • Stanley Ho Centre for Emerging Infectious Diseases

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

18年 及以上 (成人、年长者)

接受健康志愿者

有资格学习的性别

男性

取样方法

非概率样本

研究人群

Adult men who have sex with men in Hong Kong

描述

Inclusion Criteria:

  • male
  • had sex with another male in the preceding year
  • able to communicate in written Chinese or English
  • normally resided in Hong Kong

Exclusion Criteria:

  • prisoners
  • having mental illnesses that informed consent cannot be obtained

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 观测模型:队列
  • 时间观点:横截面

队列和干预

团体/队列
干预/治疗
Men who have sex with men
MSM receiving a self-test kit with optional assistance
fingerprick and oral fluid HIV self-tests with optional on-site or hotline staff assistance
Gamification or neumorphism user interface

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
effectiveness of the approach in reaching MSM who have never or not recently tested for HIV
大体时间:Through study completion, at year 2
proportion of testers who have never or not recently tested for HIV
Through study completion, at year 2
Usability and acceptability of two user interfaces
大体时间:Through study completion, at year 2
System Usability Scores (SUS) and proportion of testers giving a score of at least 71
Through study completion, at year 2

次要结果测量

结果测量
措施说明
大体时间
Determinants of key actors in the social network
大体时间:Through study completion, at year 2
Network metrics predicting important actors in the referral network
Through study completion, at year 2
Preference of two forms of HIV self-testing
大体时间:Through study completion, at year 2
Proportion of testers favouring each form of self-testing
Through study completion, at year 2
Effect of network-based HIV self-test promotion in controlling transmission among MSM
大体时间:Through study completion, at year 2
Number of infections identified from the agent-based model
Through study completion, at year 2
Proportion and characteristics of promoters
大体时间:Through study completion, at year 2
Promoters are testers giving an SUS score of at least 80
Through study completion, at year 2

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

一般刊物

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2021年3月1日

初级完成 (实际的)

2021年5月12日

研究完成 (实际的)

2021年5月12日

研究注册日期

首次提交

2020年5月2日

首先提交符合 QC 标准的

2020年5月6日

首次发布 (实际的)

2020年5月7日

研究记录更新

最后更新发布 (实际的)

2022年1月11日

上次提交的符合 QC 标准的更新

2021年12月19日

最后验证

2021年12月1日

更多信息

与本研究相关的术语

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)?

药物和器械信息、研究文件

研究美国 FDA 监管的药品

研究美国 FDA 监管的设备产品

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

艾滋病毒感染的临床试验

HIV self-test kit的临床试验

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