Project Healthy Eating in Children. A Study on the Health Effects of Fish Intake in Overweight Children

Title in Norwegian: Ung og Frisk. En Studie av Helseeffekter av Fiskeinntak i Overvektige Barn.

It has previously been seen that increased fish intake improves the metabolic health of overweight and obese adults, and animal protein improved metabolic health of obese rats. In this project the investigators will investigate whether increased intake of fish or meat improve metabolic health in children aged 9-12 years as well when replacing processed food. The hypothesis is that increased intake of unprocessed fish or meat will improve metabolic health in children as measured by glucose tolerance, lipid metabolism and inflammatory markers.

Study Overview

• Status: Terminated
• Conditions: Healthy
• Intervention / Treatment: Other: Salmon Group; Other: Cod Group; Other: Meat Group

• Study Type: Observational
• Enrollment (Actual): 25

Contacts and Locations

Study Locations

• Norway
  • Bergen, Norway, 5021
    • University of Bergen

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 9 years to 12 years (Child)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Cildren aged 9-12 years are invited to participate in the study. The children must be healthy and not use prescription medications that affects lipid metabolism, glucose regulation or the immunesystem.

Description

Inclusion Criteria:

• overweight (iso-BMI > 25)
• 9-12 years
• healthy

Exclusion Criteria:

• diagnosed diseases such as diabetes, CVD, intestinal diseases, arthritis
• prescription medications affecting the metabolism of glucose, lipids or the immune system
• use of supplements containing long chain n-3 fatty acids
• high intake of fish
• food allergy

Study Plan

How is the study designed?

Number of groups / cohorts

3

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Salmon Group; Participants will eat 75 - 150 grams of salmon for dinner, three times a week for 12 weeks.	Other: Salmon Group; The children are advised to eat at least 75g of salmon per serving, but no more than 150g
Cod Group; Participants will eat 75-150 grams of cod for dinner, three times a week for 12 weeks.	Other: Cod Group; The children are advised to eat at least 75g of cod per serving, but no more than 150g
Meat Group; Participants will eat 75-150 grams of mixed meat for dinner, three times a week for 12 weeks.	Other: Meat Group; The children are advised to eat at least 75g of meat per serving, but no more than 150g

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Changes in metabolic status (glucose, lipids, inflammation)	We will investigate any changes in the metabolic status by analyzing parameters affected by changes in glucose homeostasis, lipid metabolism and inflammation.	Baseline and end of intervention period (12 weeks)

Secondary Outcome Measures

Outcome Measure	Time Frame
Body composition	Baseline and end of intervention (12 weeks)

Collaborators and Investigators

• Sponsor: University of Bergen
• Collaborators: The Fisheries and Aquaculture Industry Research Fund
• Investigators: Principal Investigator: Oddrun A Gudbrandsen, PhD, University of Bergen

Study record dates

Study Major Dates

• Study Start: August 1, 2014
• Primary Completion (Actual): August 1, 2015
• Study Completion (Actual): August 1, 2015

Study Registration Dates

• First Submitted: December 17, 2013
• First Submitted That Met QC Criteria: December 30, 2013
• First Posted (Estimate): January 1, 2014

Study Record Updates

• Last Update Posted (Estimate): May 24, 2016
• Last Update Submitted That Met QC Criteria: May 22, 2016
• Last Verified: May 1, 2016

More Information

Terms related to this study

• Keywords: Children; Age 9-12 years; Overweight (iso-BMI > 25)
• Additional Relevant MeSH Terms: Body Weight; Overweight
• Other Study ID Numbers: 2013/541