Gender in Face-Voice Integration (Face-Voice)

August 29, 2018 updated by: Hospices Civils de Lyon

Neural Correlates of Multimodal Face/Voice Processing in a Gender Task.

Bayesian models of perception represent a promising approach to describe information processing by the brain. Predictive coding hypothesizes a process in which top-down expectations are continuously compared across multiple hierarchical levels with bottom-up sensory inputs and the differences or error signals are propagated in a bottom-up direction. The investigators hypothesize that strong expectations, are best investigated in expert processes such as face and voice recognition in humans. Individuals in complex social systems need to extract socially relevant information in a fast and efficient manner; hence, the majority of humans constitute face, voice and gender experts. Nevertheless, linking such combined abilities to brain activity with regards to the predictive coding hypothesis has not been attempted.Our results suggest asymmetric contributions of visual and auditory signals to the gender classification task. This sensitive psychophysical procedure is implemented in a decoding approach using fMRI and multi-voxel pattern analysis (MVPA). The investigators plan to test whether cortical areas implicated in processing auditory and visual gender signals show similar asymmetries.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

38

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • France
      • Bron, France, 69 500
        • Le Vinatier

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 40 years (Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Healthy men and women, right-handed
  • No neurological antecedent
  • Signed informed consent

Exclusion Criteria:

  • Pregnant women
  • Volunteers with MRI contraindications: persons using a pacemaker or insulin pump, persons with a metallic prosthesis or an intracerebral clip, as well as claustrophobic subjects, neurosensory stimulator or implantable defibrillator, cochlear implants, body Foreign ferromagnetic ocular or cerebral close to nerve structures, agitation of the subject (non-cooperating or agitated subjects), ventriculoperitoneal neurosurgical bypass valves, dental apparatus.
  • Persons under guardianship, curatorship or any other administrative or judicial measure of deprivation of rights or liberty, as well as persons of legal age protected by law.
  • Participants refusing to be informed of the results of the medical examination (inclusion).
  • Participants refusing to be informed of the possible detection of an anomaly.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Other: fMRI study
Other: fMRI study
Functional brain activations of face-voice processing during a gender task

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Identify neural correlates (fMRI) of face / voice interaction in a gender classification task
Time Frame: Maximum 90 days between inclusion of the subject and the 1st fMRI session (1h1 / 2). Then maximum 90 days before the 2nd session (1h1 / 2).
Classical functional analyses (GLM) and advanced statistical analyses of brain activations (BrainVoyager and Matlab softwares).
Maximum 90 days between inclusion of the subject and the 1st fMRI session (1h1 / 2). Then maximum 90 days before the 2nd session (1h1 / 2).
Identify neural correlates (fMRI) of face / voice respective contribution in a gender classification task
Time Frame: Maximum 90 days between inclusion of the subject and the 1st fMRI session (1h1 / 2). Then maximum 90 days before the 2nd session (1h1 / 2).
Classical functional analyses (GLM) and advanced statistical analyses of brain activations
Maximum 90 days between inclusion of the subject and the 1st fMRI session (1h1 / 2). Then maximum 90 days before the 2nd session (1h1 / 2).

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Hospices Civils de Lyon

Investigators

  • Principal Investigator: Alain NICOLAS, MD, Le Vinatier

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 20, 2016

Primary Completion (Actual)

May 28, 2018

Study Completion (Actual)

May 28, 2018

Study Registration Dates

First Submitted

February 8, 2017

First Submitted That Met QC Criteria

February 15, 2017

First Posted (Actual)

February 20, 2017

Study Record Updates

Last Update Posted (Actual)

August 31, 2018

Last Update Submitted That Met QC Criteria

August 29, 2018

Last Verified

August 1, 2018

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 69HCL16_0674

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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