Emotional Perception and Production in Facial Palsy: Respiratory, Vocal and Facial Markers. (ResPPF)

Production et Perception émotionnelle Chez Les Patients paralysés Faciaux: Marqueurs Respiratoires, Phonatoires et expressivité Faciale.

Respiratory function, phonation and facial expressivity are related to emotional reaction through neurophysiological process. Specific emotional respiratory, vocal and facial patterns had been described in literature. Respiratory cycles variation is modulated by stimulus arousal. Furthermore, inspiratory-to-expiratory time ratio in abdominal area is modulated by emotional valence. Inextricably linked to respiration, vocal production depends on emotional arousal and valence too.

According to embodied cognition, the effector pattern of an emotion initiates the corresponding subjective activation. Facial recognition is influenced by automatic mimicry and facial feedback. Most facial feedback studies included patients with diplegia but few studies dealt with emotional perception in Bell's palsy.

The aim of the present study is to understand production and perception of emotion in Bell's palsy with respiratory, vocal and facial markers. What impact lack of mimicry have on physiological emotional reaction in Bell's palsy? To this end, prospective monocentric study will be conducted with 60 patients with Bell's Palsy from grade II to grade VI of House & Brackmann's scale. During production and perception of vocal and facial expression, respiratory rate and thoraco-abdominal movements will be analyzed. The investigators hypothesize that severity of facial deficit is negatively correlated with variation of respiratory cycles, lower segmental and suprasegmental changes during vocal expression, and lower facial perception (congruency and arousal).

Study Overview

• Status: Completed
• Conditions: Facial Palsy
• Intervention / Treatment: Other: Records

• Study Type: Interventional
• Enrollment (Actual): 60
• Phase: Not Applicable

Contacts and Locations

Study Locations

• France
  • Paris, France, 75013
    • Laboratoire de Physiopathologie Respiratoire du Service de Pneumologie et de Réanimation

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Patients affiliated to the health care system
• Patients must have been diagnosed with unilateral peripheral facial palsy stage III to VI, according to House and Brackmann international classification.
• To be able to read, understand and sign a consent
• To be able to understand French spoken and written

Exclusion Criteria:

• Diplegia or facial graft
• Visual disorders, non corrected
• Respiratory or vocal disorders
• Psychiatric history
• Facial surgery

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Screening
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Participants	Other: Records; Respiratory records, Vocal records Video records Questionnaires

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Effects of facial impairment on the respiratory rate	Facial impairment assesed with Sunnybrook Facial Grading Scale Composite Score in %. Respiratory rate is measured with chest and abdominal belt (breaths per minute).	1hour

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Effects of facial impairment on pitch variation (Hz) during emotional vocal production.	Acoustic measures lead with Praat Analysis software. Variation pitch between first and last segment of the emotional sentence calculated in Herz.	1hour
Effects of facial impairment on perception of emotional facial displays.	Emotional facial displays perception measured with a standardized emotional program in terms of congruency (total score and standard deviation).	1hour

Collaborators and Investigators

• Sponsor: Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
• Investigators: Principal Investigator: Peggy Gatignol, Laboratoire de physiopathologie respiratoire, UMR_S 1158 INSERM/UPMC " Neurophysiologie Respiratoire Expérimentale et Clinique "

Study record dates

Study Major Dates

• Study Start (Actual): August 11, 2018
• Primary Completion (Actual): September 25, 2019
• Study Completion (Actual): April 10, 2020

Study Registration Dates

• First Submitted: July 21, 2018
• First Submitted That Met QC Criteria: August 2, 2018
• First Posted (Actual): August 8, 2018

Study Record Updates

• Last Update Posted (Actual): August 14, 2020
• Last Update Submitted That Met QC Criteria: August 13, 2020
• Last Verified: July 1, 2020

More Information

Terms related to this study

• Keywords: Emotions, Respiratory Rate, Phonation
• Additional Relevant MeSH Terms: Pathologic Processes; Nervous System Diseases; Virus Diseases; Infections; Neurologic Manifestations; Disease Attributes; Stomatognathic Diseases; Mouth Diseases; DNA Virus Infections; Cranial Nerve Diseases; Herpesviridae Infections; Paralysis; Facial Nerve Diseases; Bell Palsy; Facial Paralysis; Facies
• Other Study ID Numbers: 2018-A01043-52

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No