Self-estimates and Objective Blood Alcohol Concentration in Emergency Department (SEOBACED)

Self-estimates and Objective Measurement of Blood Alcohol Concentration in Patients With Alcohol Intoxication Presenting to an Emergency Department

Many patients presenting in Emergency Department (ED) present alcohol acute intoxication. Some previous studies in general population found that young people under- or over-estimated of blood alcohol concentration (BAC). The hypothesis of the study is that self-estimation of BAC by the patient is under-estimated. Moreover, comparing self-estimation of BAC and objective measure of BAC, which is routinely performed in ED, could increase in patients the awareness of the disorders, increase motivation to change of the patient, and increase the rates of seeking-treatment six months after the first evaluation, in particular in patients with alcohol use disorders.

To the investigators knowledge, there is no study investigating self-estimation, compared to objective measurement of blood alcohol concentration in patients with alcohol intoxication presenting to an Emergency Department (ED). The study will assess blood alcohol concentration and self-estimates of BAC, using the Subjective Effects of Alcohol Scale for Measuring Subjective Response to Alcohol in 100 patients with or without alcohol use disorders according to DSM-5 classification (using MINI scale and Alcohol Use Disorders Identification Test (AUDIT)

Study Overview

• Status: Completed
• Conditions: Alcohol Use Disorder; Blood Alcohol Content
• Intervention / Treatment: Biological: blood alcohol concentration withdrawal

• Study Type: Interventional
• Enrollment (Actual): 34
• Phase: Not Applicable

Contacts and Locations

Study Locations

• France
  • Amiens, France, 80480
    • CHU Amiens

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 15 years to 64 years (Child, Adult)
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Patients admitted in Emergency Department while intoxicated will be included in the study, including patients with or without alcohol use disorders according to DSM-5 classification.
• aged 15-64 years old
• patients who will be orally informed and receive a written summary
• blood alcohol concentration of 60mg/dl or higher
• Patients not opposed to participating in the study, who have received an oral and written information

Exclusion Criteria:

• Drug intoxication (cannabis, opiates, amphetamines, cocaine), psychotropic medication intoxication (benzodiazepines, antipsychotics), primary neurologic conditions, mental retardation, dementia, amnestic disorders, mental disorders due to a general, medical condition and substance-induced psychotic disorders.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: patients with alcohol use disorders	Biological: blood alcohol concentration withdrawal; The blood alcohol concentration is systematically performed in all intoxicated patients admitted in Emergency Department
Experimental: patients without alcohol use disorders	Biological: blood alcohol concentration withdrawal; The blood alcohol concentration is systematically performed in all intoxicated patients admitted in Emergency Department

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Mean change between real blood alcohol concentration and self-estimated blood alcohol concentration	Comparison of real blood alcohol concentration and self-estimated blood alcohol concentration	Day =0 (day of patient inclusion)

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Mean change between real blood alcohol concentration and self-estimated blood alcohol concentration in patient with alcohol use disorders	Comparison of real blood alcohol concentration and self-estimated blood alcohol concentration with alcohol use disorders according DSM-5 classification (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)	Day =0 (day of patient inclusion)
Mean change between real blood alcohol concentration and self-estimated blood alcohol concentration in patient without alcohol use disorders	Comparison of real blood alcohol concentration and self-estimated blood alcohol concentration without alcohol use disorders according DSM-5 classification (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)	Day =0 (day of patient inclusion)
Measure motivation to change during the first interview at the Emergency Department	Measure motivation to change during the first interview at the Emergency Department	Day =0 (day of patient inclusion)
Measure motivation to change six months following the first interview at the Emergency Department	Measure motivation to change six months following the first interview at the Emergency Department	six months following the first interview at the Emergency Department

Collaborators and Investigators

• Sponsor: Centre Hospitalier Universitaire, Amiens
• Investigators: Principal Investigator: Alain Dervaux, Pr, CHU Amiens

Publications and helpful links

General Publications

• DOI:10.1016/j.euroneuro.2020.09.032 November 2020European Neuropsychopharmacology 40(4):S20 P.029 Self-estimation of blood alcohol concentration in patients admitted for acute alcohol intoxication in emergency department

Study record dates

Study Major Dates

• Study Start (Actual): June 18, 2019
• Primary Completion (Actual): June 18, 2020
• Study Completion (Actual): June 18, 2020

Study Registration Dates

• First Submitted: June 21, 2019
• First Submitted That Met QC Criteria: June 25, 2019
• First Posted (Actual): June 26, 2019

Study Record Updates

• Last Update Posted (Estimated): November 19, 2025
• Last Update Submitted That Met QC Criteria: November 17, 2025
• Last Verified: November 1, 2025

More Information

Terms related to this study

• Keywords: Emergency Department; Alcohol use disorders; blood alcohol concentration
• Additional Relevant MeSH Terms: Mental Disorders; Pathologic Processes; Disease Attributes; Substance-Related Disorders; Chemically-Induced Disorders; Alcohol-Related Disorders; Pathological Conditions, Signs and Symptoms; Emergencies; Alcoholism; Organic Chemicals; Investigative Techniques; Specimen Handling; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Punctures; Surgical Procedures, Operative; Alcohols; Ethanol; Blood Specimen Collection
• Other Study ID Numbers: PI2018_843_0009

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No