Ultrasonic Measurement of IVC and IJV in Predicting Hypotension After Anesthesia Induction

Ultrasonic Measurement of Inferior Vena Cava and Internal Jugular Vein in Predicting Hypotension After Anesthesia Induction in Patients Undergoing Gastrointestinal Surgery

This research is expected to study ultrasonic measurement of internal jugular vein and inferior vena cava, which can be used as a good index to predict hypotension after anesthesia induction, and its measurement method is simple and quick.

Study Overview

• Status: Unknown
• Conditions: Anesthesia

Detailed Description

The induction of anesthesia is the process from the physiological state to the anesthetic state in a short period of time. Hypotension after anesthesia induction is closely related to many organ injuries. Gastrointestinal surgery patients' prohibition of fasting is an important mechanism of severe hypotension after anesthesia induction. At present, ultrasonic measurement of inferior vena cava and internal jugular vein has been proved to be a convenient and non-invasive means to evaluate patients' blood volume. The purpose of this research was to study the relativity between ultrasonic measurement of inferior vena cava and internal jugular vein and hypotension after anesthesia induction in patients.

• Study Type: Observational
• Enrollment (Anticipated): 150

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 60 years to 75 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

patients undergoing gastrointestinal surgery in the Affiliated Hospital of Xuzhou Medical University

Description

Inclusion Criteria:

• Gastrointestinal surgery
• BMI 18~24
• ASA score gradeⅠ~ III

Exclusion Criteria:

• anemia
• cirrhosis
• Emergency surgery
• severe hypertension
• New York Heart Association III ~ IV or ejection fraction <40%
• cirrhosis
• Other serious systemic diseases

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
hypotension; Patients with hypotension after induction of anesthesia
non-hypotension; Patients without hypotension after induction of anesthesia

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Incidence of hypotension after anesthesia Induction	Hypotension can be diagnosed if one of the following conditions is true: (1) a decrease in mean arterial pressure of > 20% compared to the baseline value (2) mean arterial pressure < 60mmHg	within 12 hours after anesthesia induction

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Ultrasonic measurement of inferior vena cava and internal jugular vein	Measure the maximum diameter, minimum diameter and cross-sectional area of inferior vena cava and internal jugular vein	within 1 hour before anesthesia induction

Collaborators and Investigators

• Sponsor: Jin Dong Liu
• Investigators: Study Director: Jin Dong Liu, The Affiliated Hospital of Xuzhou Medical University

Study record dates

Study Major Dates

• Study Start (Anticipated): May 8, 2020
• Primary Completion (Anticipated): December 30, 2020
• Study Completion (Anticipated): December 30, 2020

Study Registration Dates

• First Submitted: May 1, 2020
• First Submitted That Met QC Criteria: May 6, 2020
• First Posted (Actual): May 7, 2020

Study Record Updates

• Last Update Posted (Actual): May 7, 2020
• Last Update Submitted That Met QC Criteria: May 6, 2020
• Last Verified: May 1, 2020

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Cardiovascular Diseases; Vascular Diseases; Hypotension
• Other Study ID Numbers: XYFY2019-1202

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No