The Efficacy of Oregano Essential Oil in Reducing Oral Halitosis

The Efficacy of Oregano Essential Oil in Reducing Oral Halitosis :A Randomized Controlled Trial

the efficacy of commercially available oregano essential oil mouthwash in the reduction of oral halitosis was compared to chlorhexidine and distilled water and the results showed significant reduction of organoleptic tongue and floss scores and BANA test scores compared to placebo

Study Overview

• Status: Completed
• Conditions: Halitosis
• Intervention / Treatment: Other: oregawash; Other: placebo; Other: corsodyl

Detailed Description

the results showed that oregawash showed a comparable effect to chx in reducing oral halitosis

• Study Type: Interventional
• Enrollment (Actual): 54
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Iraq
  • Rasafa
    • Baghdad, Rasafa, Iraq, 00964
      • Univeristy of Baghdad

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 16 years to 21 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

1. Organoleptic score was >2 at baseline.
2. Participants between 18-23 years of age.
3. The subjects had no systemic disease and were not taking antibiotics or receiving other antimicrobial therapy.
4. The subjects did not receive the same time treatment for their halitosis.

Exclusion Criteria:

1. Smokers, alcoholics and drug addicts.
2. Patients with periodontitis or pocket depth >6 mm.
3. Patients taking drugs which induced xerostomia.
4. Subjects consuming spicy food: garlic or onions two days before examination.
5. Patients with orthodontic appliances or removable dentures.
6. pregnancy

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: oregano; oregawash mouthwash was used twice times daily for 7 days	Other: oregawash; mouthwash containing oregano essential oil
Placebo Comparator: placebo; distilled water was used twice times daily for 7 days	Other: placebo; distilled water; Other Names: distilled water
Active Comparator: chlorhexidine; Corsodyl with 0.2%CHX mouthwash was used twice times daily for 7 days	Other: corsodyl; 0.2% chlorhexidine mouthwash; Other Names: chlorhexdine

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
organoleptic tongue and floss scores	organoleptic measuements	9 month

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
BANA test	chair side BANA test	9 month

Collaborators and Investigators

• Sponsor: MOHAMED SAEED M. ALI
• Investigators: Principal Investigator: mohamed s albana, director, Univeristy of Baghdad

Study record dates

Study Major Dates

• Study Start (Actual): January 12, 2020
• Primary Completion (Actual): November 15, 2020
• Study Completion (Actual): November 17, 2020

Study Registration Dates

• First Submitted: February 27, 2021
• First Submitted That Met QC Criteria: February 27, 2021
• First Posted (Actual): March 3, 2021

Study Record Updates

• Last Update Posted (Actual): March 4, 2021
• Last Update Submitted That Met QC Criteria: March 2, 2021
• Last Verified: March 1, 2021

More Information

Terms related to this study

• Keywords: mouthwash; oral halitosis; oregano essential oil
• Additional Relevant MeSH Terms: Signs and Symptoms, Digestive; Halitosis; Anti-Infective Agents, Local; Anti-Infective Agents; Dermatologic Agents; Disinfectants; Chlorhexidine; Chlorhexidine gluconate
• Other Study ID Numbers: 131619

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No