The Effects of Vestibular Exercise and Cervical Stabilization Exercise Training on Balance and Gait in MS Patients

Comparison of the Effects of Vestibular Exercise and Cervical Stabilization Exercise Training on Balance and Gait in Multiple Sclerosis Patients

The population of this research consists of individuals between the ages of 18-65 with MS disease. MS patients to be included in the study will be directed by the Neurology outpatient clinic of Sanko University Hospital. All volunteers who agreed to participate in this randomized controlled pretest-posttest design study and met the sample criteria will be included in the study.Individuals who agree to participate will be divided into three groups by simple random method and closed envelope method. Vestibular exercise training group will be formed as Group 1 and Cervical stabilization exercise training group as Group 2, control group, and Group 3 as control group.Functional reach test, tandem stand test, 25 step walking test scale form, Multiple Sclerosis Quality of Life Scale form ( MSQOL-54),Fatigue Impact Scale,Beck depression inventory, MS walking scale (msys-12), dizziness disability inventory, four step square test, timed sit and stand test

, 2 minutes walking test be performed before and after treatment,

Study Overview

• Status: Recruiting
• Conditions: Multiple Sclerosis; Exercises; Vestibular
• Intervention / Treatment: Other: Exercises

Detailed Description

Group 1: Vestibular exercise training will be given in addition to conventional treatment (including TENS, electrical stimulation and normal joint range of motion exercises) for 12 weeks. Cawthorne-Cooksey Exercises will be given as a treatment protocol for vestibular exercise training.

Group 2 :Cervical stabilization exercise training will be given in addition to conventional treatment (including Tens, electrical stimulation and normal range of motion exercises) for 12 weeks. Cervical stabilization training improves the sense of cervical proprioception as well as strength and endurance, thereby reducing joint position sense error. Cervical stabilization exercises and training, consisting of 3 stages with increasing difficulty level, will be applied.

Group3: Classical balance exercise training will be given to the control group in addition to conventional treatment (including Tens, electrical stimulation and normal range of motion exercises) for 12 weeks. These exercises were selected among the exercises routinely used in balance rehabilitation in the literature and clinic.

Balance exercise program: walking on tiptoe and heel, walking straight and diagonally on the line, standing on a balance board, supine/prone rolling on the rehabilitation ball, pelvis control in the sagittal and frontal planes on the rehabilitation ball, prone balance on the rehabilitation ball, walking on mats of different softness , was created from side walking exercises.

• Study Type: Interventional
• Enrollment (Anticipated): 36
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Hakan Polat; Phone Number: 05386487265; Email: hakan.polat@sanko.edu.tr

Study Locations

• Turkey
  • Şehitkamil
    • Gaziantep, Şehitkamil, Turkey, 27500
      • Recruiting
      • SANKO University
      • Contact: Hakan Polat; Phone Number: 05386487265; Email: hakan.polat@sanko.edu.tr

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 65 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• be diagnosed with MS
• Not having received physiotherapy-oriented treatment in the last 1 year
• not have had an attack in the last 1 month and not be in the attack period

Exclusion Criteria:

• having systemic diseases such as hypertension, heart disease, diabetes mellitus, hyperlipidemia, malignancy
• individuals whose ambulation is not independent
• Those who have undergone any surgery in the last 6 months

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Vestibular Exercises; Cawthorne-Cooksey Exercises applied to 1st group for 3 days/week for 12 weeks	Other: Exercises; Exercises
Active Comparator: Cervical Stabilization Exercises; cervical stabilization Exercises applied to 1st group for 3 days/week for 12 weeks	Other: Exercises; Exercises
Active Comparator: Balance Exercises; classical balance Exercises applied to 1st group for 3 days/week for 12 weeks	Other: Exercises; Exercises

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Static Balance	functional reach test	12 weeks
Gait speed	25-step walking test	12 weeks
Dizziness	dizziness disability inventory	12 weeks
Dinamic Balance	tandem stance test	12 weeks
Dinamic Balance	4 square step test	12 weeks
Endurance	2-minute walk test	12 weeks
Coordination	timed sit and stand test	12 weeks
Postural swing	GYKO	12 weeks
Walkiing difficulty	Multiple Sclerosis Walking Scale-12 (MSYS-12)	12 Weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Fatigue	fatigue impact scale	12 weeks
Depression	beck depression inventory	12 weeks
MSQ54 İnventory	quality of life	12 weeks

Collaborators and Investigators

• Sponsor: Sanko University
• Investigators: Study Director: hakan Polat, SANKO University

Study record dates

Study Major Dates

• Study Start (Actual): October 1, 2021
• Primary Completion (Anticipated): January 25, 2023
• Study Completion (Anticipated): February 1, 2023

Study Registration Dates

• First Submitted: April 8, 2022
• First Submitted That Met QC Criteria: June 2, 2022
• First Posted (Actual): June 8, 2022

Study Record Updates

• Last Update Posted (Actual): January 23, 2023
• Last Update Submitted That Met QC Criteria: January 18, 2023
• Last Verified: January 1, 2023

More Information

Terms related to this study

• Keywords: Multiple Sclerosis; gait; vestibular exercises; cervical stabilization
• Additional Relevant MeSH Terms: Pathologic Processes; Nervous System Diseases; Immune System Diseases; Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Demyelinating Diseases; Autoimmune Diseases; Multiple Sclerosis; Sclerosis
• Other Study ID Numbers: HakanP

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No