- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05635526
Assessment of Corneal Biomechanics With the Corvis ST in Different Age of Myopia With Orthokeratology
November 22, 2022 updated by: Tianjin Eye Hospital
The present research focused on the effect of the age for the corneal biomechanics of low and moderate myopia patients after wearing orthokeratology (OK lens).
According to age, the included cases were divided into 3 groups.
Through the analysis of corneal biomechanical parameters, further learn the influence of OK lens on the patient cornea.
It would help ophthalmologist and optometrist find out the potential issue and reach a better control result.
Study Overview
Status
Completed
Conditions
Detailed Description
The present research focused on the effect of the age for the corneal biomechanics of low and moderate myopia patients after wearing orthokeratology (OK lens).
According to age, the included cases were divided into 3 groups: Ⅰ (8-12 years old), Ⅱ (13-16 years old), Ⅲ (over 16 years old).
The OK lenses used in the present study are of the same design (Euclid Systems Orthokeratology; Euclid System, Herndon, VA, USA).
The base line (Day 0) and different follow-up time point (Day 1, Week 1, Week 2, Month 1, Month 3, and Month 6) of dynamic corneal response (DCR) (including 19 items) of the patients derived by Corvis ST were collected.
The difference between before and after wearing OK Lens and the changes of parameters among the three groups were both analyzed.
And the correlation between axis length (AL) and the 19 parameters also was analyzed.
Through the analysis of corneal biomechanical parameters, further learn the influence of OK lens on the patient cornea.
It would help ophthalmologist and optometrist find out the potential issue and reach a better control result.
Study Type
Observational
Enrollment (Actual)
134
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Tianjin
-
Tianjin, Tianjin, China
- Tiajin Eye Hospital
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
8 years to 40 years (Child, Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
Myopia with orthokeratology lens and complete follow-up.
Description
Inclusion Criteria:
- age from 8 to 40 years old
- spherical equivalent(SE) was range from -1.00D to -5.00D
- conform to the standard of wearing orthokeratology lens
Exclusion Criteria:
- ocular diseases and systemic diseases
- visual acuity was less than 20/20
- unable to follow visitors on time
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Observational Models: Other
- Time Perspectives: Retrospective
Cohorts and Interventions
Group / Cohort |
---|
1
8-12 years old
|
2
13-16 years old
|
3
over 16 years old
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
The change of dynamic corneal response (DCR)
Time Frame: The change of baseline and 1 day, 1 week, 2 weeks, 1 month, 3 months, and 6 months
|
The axial length was measured by Corvis ST
|
The change of baseline and 1 day, 1 week, 2 weeks, 1 month, 3 months, and 6 months
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
The change of axial length
Time Frame: The change of baseline and 6 months
|
The axial length was measured by AL-scan
|
The change of baseline and 6 months
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
June 1, 2020
Primary Completion (Actual)
June 1, 2021
Study Completion (Actual)
October 1, 2022
Study Registration Dates
First Submitted
November 22, 2022
First Submitted That Met QC Criteria
November 22, 2022
First Posted (Actual)
December 2, 2022
Study Record Updates
Last Update Posted (Actual)
December 2, 2022
Last Update Submitted That Met QC Criteria
November 22, 2022
Last Verified
October 1, 2022
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 2022049
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
No
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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