Interstitial Lung Disease and Obstructive Sleep Apnea

October 26, 2023 updated by: Dan Liu

Study on the Clinical Characteristics of Interstitial Lung Disease and Obstructive Sleep Apnea

Clinically, all patients with interstitial lung disease were observed, and relevant clinical data were collected. Bronchoscopic specimens were collected according to the condition of the enrolled patients, and the ROSE smear was evaluated, combined with the NGS results of these patients. To observe the etiology and biological characteristics of exacerbation in patients with interstitial lung disease.

Patients with apnea should be tested for polysomnography, and corresponding biological specimens should be obtained for molecular biology or other tests

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

70

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • China
      • Tianjin, China, 300000
        • Recruiting
        • Tianjin Medical University General Hospital
        • Contact:
        • Contact:
        • Principal Investigator:
          • Dan Liu

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Interstitial lung disease and respiratory sleep apnoea

Description

Inclusion criteria:

  • over 18 years old and under 80 years old.
  • Clinical diagnosis of interstitial lung disease or obstructive respiratory sleep apnea syndrome.
  • Patient is conscious and capable of signing informed consent.
  • The patient may wear a polysomnograph.

Exclusion criteria:

  • malignant tumors.
  • severe heart failure.
  • uremia.
  • autoimmune diseases.
  • pulmonary embolism, and end-stage chronic obstructive pulmonary disease.
  • Patients with mental illnesscannot sign informed consent on their own.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
OSA group
Sleep detection was performed in OSA patients，And according to the severity of the analysis, obtain the corresponding biological specimens, the relevant detection
Diagnostic test: The relationship between imaging and ROSE and NGS
The correlation between ROSE and NGS in imaging and bronchoscopy of ILD patients was observed
Other Names:
  • Association between the severity of OSA and biological specimen examination
Interstitial lung disease group
Bronchoscopy was performed to obtain alveolar lavage fluid in ILD patients and lung tissue was obtained for ROSE and NGS in appropriate patients
Diagnostic test: The relationship between imaging and ROSE and NGS
The correlation between ROSE and NGS in imaging and bronchoscopy of ILD patients was observed
Other Names:
  • Association between the severity of OSA and biological specimen examination

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
imaging changes and ROSE and NGS in patients
Time Frame: 2Day
Relationship between imaging changes and ROSE and NGS in patients with interstitial lung disease
2Day

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Severity and biological examination of OSA patients
Time Frame: 2Day
Classification of the severity of OSA and the relationship between positive results of biological or other tests
2Day

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Dan Liu

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 1, 2023

Primary Completion (Estimated)

December 31, 2023

Study Completion (Estimated)

December 31, 2023

Study Registration Dates

First Submitted

April 10, 2023

First Submitted That Met QC Criteria

April 20, 2023

First Posted (Actual)

May 1, 2023

Study Record Updates

Last Update Posted (Actual)

October 27, 2023

Last Update Submitted That Met QC Criteria

October 26, 2023

Last Verified

October 1, 2023

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Dliu

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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