Smoking Cessation, Anxiety, Pain Relationship

Preoperative Smoking Cessation, Preoperative Anxiety, Postoperative Anxiety and Pain Relationship

Smoking, anxiety and pain are clearly related conditions. We aimed to reveal the relationship between smoking cessation before surgery and preoperative anxiety, postoperative anxiety and pain in chronic smokers.

METHODS ASA I-II group patients without chronic disease and history of drug use were included in the study. Those who did not want to participate in the study, patients with ASA III and above were excluded from the study. The patients were randomized into 2 groups: smokers (Group S, n = 60) and non-smokers (Group NS, n = 60). Group S was asked to quit smoking 2 weeks before the operation. Preoperative period and postoperative 0, 2, 4. And 6. hour Spielberger State-Trait Anxiety Inventory (STAI) values, postop 0., 2., 4., 6. hour Visual Analogue Scale (VAS) values were recorded.

Study Overview

• Status: Completed
• Conditions: Smoking Cessation; Pain; Anxiety
• Intervention / Treatment: Other: The Relationship Between Preoperative Smoking Cessation, Anxiety, Pain

Detailed Description

it has been revealed in the current study that smoking, pain and anxiety are interrelated with each other. In the preoperative period, high anxiety scores are related to surgery and anesthesia stress. High anxiety scores in the smoker group both in the preoperative period and in the postoperative period are associated with smoking cessation. While the pain scores were similar in the postoperative period, high anxiety scores strengthened the idea of smoking withdrawal and this study gained value. We believe that future studies with a large number of patients, with different parameters and multiple centers will strengthen the results.

• Study Type: Interventional
• Enrollment (Actual): 120
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey
  • Tuşba
    • Van, Tuşba, Turkey, 65080
      • Van Yuzuncu Yil University Faculty of Medicine Department of anesthesiology and reanimation
    • Van, Tuşba, Turkey, 65080
      • Van Yüzüncü Yil University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 20 years to 60 years (ADULT)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• ASA I,II patients
• planned Rhinoplasti cases
• accepted participating study

Exclusion Criteria:

• Patients with chronic systemic disorders,
• ASA III and above situation
• emergency and bleeding cases,
• patients with any cardiac and neurological disorders,
• refused to participate in the study

Study Plan

How is the study designed?

Design Details

• Primary Purpose: OTHER
• Allocation: NON_RANDOMIZED
• Interventional Model: CROSSOVER
• Masking: NONE

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
SHAM_COMPARATOR: smokers (S)	Other: The Relationship Between Preoperative Smoking Cessation, Anxiety, Pain; Preoperative anxiety high score suggests stress related to surgery and anesthesia. High anxiety scores independent of post-operative pain showed smoking withdrawal.
ACTIVE_COMPARATOR: non smokers (NS)	Other: The Relationship Between Preoperative Smoking Cessation, Anxiety, Pain; Preoperative anxiety high score suggests stress related to surgery and anesthesia. High anxiety scores independent of post-operative pain showed smoking withdrawal.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Anxiety	assesed with STAI form	2 hours

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
pain scores	independent of anxiety, assesed with VAS scores	2 hours

Collaborators and Investigators

• Sponsor: Yuzuncu Yıl University
• Investigators: Principal Investigator: Arzu Esen Tekeli, MD, yuzuncu yil

Study record dates

Study Major Dates

• Study Start (ACTUAL): February 17, 2018
• Primary Completion (ACTUAL): February 18, 2019
• Study Completion (ACTUAL): January 13, 2020

Study Registration Dates

• First Submitted: May 18, 2020
• First Submitted That Met QC Criteria: May 22, 2020
• First Posted (ACTUAL): May 28, 2020

Study Record Updates

• Last Update Posted (ACTUAL): May 28, 2020
• Last Update Submitted That Met QC Criteria: May 22, 2020
• Last Verified: May 1, 2020

More Information

Terms related to this study

• Keywords: pain; anxiety; Smoking Cessation; VAS Scores; STAI Values
• Additional Relevant MeSH Terms: Mental Disorders; Anxiety Disorders
• Other Study ID Numbers: 2018/05

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED
• IPD Plan Description: I do not want to share before publishing

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No