Influence of Selected Lower Limb Biomechanical Variables on Pain, Disability and Balance in Women With PFPS.

Influence of Selected Lower Limb Biomechanical Variables on Pain, Disability and Balance in Women With Patellofemoral Pain Syndrome: A Cross Sectional Study.

Purpose: The aim of this study is to figure out how does the selection of lower-extremity biomechanical variables presented by dynamic knee valgus, tibial torsion and navicular drop may influence pain, disability, and balance in women with patellofemoral pain syndrome.

Methods: Sixty-five women with patellofemoral pain syndrome will be evaluated for lower limb biomechanical variables.

Study Overview

• Status: Completed
• Conditions: Patellofemoral Pain Syndrome; Patellofemoral Malalignment Syndrome

Detailed Description

Subjects:

Sixty five women who will be referred by an Orthopedist with patellofemoral pain syndrome diagnosis.

Inclusion criteria:

Women were enrolled in this study according to the following criteria:

1. Female participants with patellofemoral pain syndrome.
2. Age ranges between 18 and 38 years old.
3. Bilateral or unilateral involvement.
4. Minimum score (3 out of 10-point) numerical pain scale (NPR) .
5. Orthopedic clinical confirmation revealing a history of anterior or retro-patellar knee pain aggravated by at least 2 of the following functional activities: 1. prolonged sitting, 2. stairs use, 3. squatting, 4. running, 5. kneeling, 6. hopping/jumping, and/or insidious onset of symptoms unrelated to any traumatic incident and persistent for at least 6 weeks.

Exclusion criteria:

A woman was excluded from the study if she has one or more of the following:

1. History of patellar dislocation or subluxation.
2. Osteoarthritis in the patellofemoral joint.
3. Meniscal or other intraarticular pathologic conditions.
4. cruciate or collateral ligament involvement.
5. Lower limb surgery.
6. Fracture, low back pain condition such as: spondylolisthesis and spondylosis.
7. Neurological deficits.
8. Traumatic injury or any abnormality in the lower extremity.

Methods: Sixty-five women with patellofemoral pain syndrome will be evaluated for dynamic knee valgus using Kinovea software program , tibial torsion using universal goniometer, and navicular drop using calliper.

Numerical pain rating scale (NPRS) will be used to measure pain severity. Arabic version of Kujala score will assess the functional disability in these patients.

Biodex Balance System will screen and will record the Medial-lateral stability index (MLSI), Anterior-posterior stability index (APSI) and an Overall stability index (OSI).

Assessments will be performed in a single session. Then correlation between these variables will be calculated.

• Study Type: Observational
• Enrollment (Actual): 165

Contacts and Locations

Study Locations

• Egypt
  • Cairo, Egypt
    • Ahmed ElMelhat [aelmelhat]

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Sixty-five women with patellofemoral pain syndrome, were included in this study. Individuals were selected from the outpatient clinics present in Cairo University and from private clinics in Cairo and Giza.

The age of selected women was ranging between 18 and 38 years old. They were able to follow instructions and understand the given commands

Description

Inclusion Criteria:

• Female participants with patellofemoral pain syndrome.
• Age ranges between 18 and 38 years old.
• Bilateral or unilateral involvement.
• Minimum score (3 out of 10-point) numerical pain scale (NPR)
• Orthopedic clinical confirmation revealing a history of anterior or retro-patellar knee pain aggravated by at least 2 of the following functional activities: 1. prolonged sitting, 2. stairs use, 3. squatting, 4. running, 5. kneeling, 6. hopping/jumping, and/or insidious onset of symptoms unrelated to any traumatic incident and persistent for at least 6 weeks.

Exclusion Criteria:

• History of patellar dislocation or subluxation.
• Osteoarthritis in the patellofemoral joint.
• Meniscal or other intraarticular pathologic conditions.
• Cruciate or collateral ligament involvement.
• Lower limb surgery.
• Fracture, low back pain condition such as: spondylolisthesis and spondylosis.
• Neurological deficits.
• Traumatic injury or any abnormality in the lower extremity

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Is there an impact of dynamic knee valgus on pain, disability and balance in women with patellofemoral pain?	Dynamic knee valgus is a biomechanical variable that will be measured by Kinovea software program to measure 2D Frontal Plane Projection Angle (2D-FPPA) .	baseline
Is there an impact of tibial torsion on pain , disability and balance in women with patellofemoral pain syndrome ?	Tibial Torsion will be measured with a universal goniometer with the participant prone on a low table, and with the tested knee bent at 90°.	baseline
Is there an impact of navicular drop on pain , disability and balance in women with patellofemoral pain syndrome ?	Each participant will be asked to stand barefoot, with weight distributed evenly over each foot. the distance between the navicular tuberosity and the floor will be measured, in millimetres, with a calliper.	baseline
Women were assessed using numerical pain rating scale (NPRS) for pain severity.	The NPRS has been extensively used to assess pain severity.The Arabic version of NPRS, has been culturally adapted and validated.	baseline
Women were assessed by Arabic version of Kujala for functional disability.	Kujala Scale, also known as anterior knee pain questionnaire (AKPS), is a self-report tool including 13 knee-specific questions. the Arabic version (AAKPS) has been tested for its validity and reliability in Arabian patients	baseline
Women were assessed by Biodex Balance System for balance.	Biodex Balance System will screen and will record the Medial-lateral stability index (MLSI), Anterior-posterior stability index (APSI) and an Overall stability index (OSI).	baseline

Collaborators and Investigators

• Sponsor: Cairo University
• Investigators: Study Director: Medhat EM [mmofty], Cairo University

Publications and helpful links

Helpful Links

• Is spinopelvic sagittal alignment correlated with pain level, functional disability and frontal plane projection angle in women with patellofemoral pain syndrome? A cross-sectional study
• Comparison of selected lower limb biomechanical variables between university of ibadan sportsmen with and without patellofemoral pain syndrome
• Evaluation of postural balance using the biodex balance system in subjects with and without low back pain

Study record dates

Study Major Dates

• Study Start (Actual): June 10, 2023
• Primary Completion (Actual): July 20, 2023
• Study Completion (Actual): August 20, 2023

Study Registration Dates

• First Submitted: April 24, 2023
• First Submitted That Met QC Criteria: April 24, 2023
• First Posted (Actual): May 3, 2023

Study Record Updates

• Last Update Posted (Actual): January 22, 2024
• Last Update Submitted That Met QC Criteria: January 18, 2024
• Last Verified: January 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pathologic Processes; Disease; Joint Diseases; Musculoskeletal Diseases; Syndrome; Patellofemoral Pain Syndrome
• Other Study ID Numbers: PFPS and lower limb alignment

Drug and device information, study documents

• Studies a U.S. FDA-regulated device product: No