- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06030336
Home Health and Air Pollution Study
April 16, 2024 updated by: Ellison Carter, Colorado State University
The goal of this clinical trial is to learn about whether indoor air quality will improve over time in homes where occupants receive personalized information about levels of health-relevant air pollutants that includes practical, budget-friendly, and culturally relevant recommendations on actions they can take to improve their home's air quality.
The rationale for the investigators' approach is that a rigorous intervention study design will generate robust evidence on the value of the in-home environmental data.
Participating homes in both the intervention and control groups will receive three, one-week Home Health Box deployments spaced six weeks apart.
After each of the first two deployments, homes in the intervention group will receive a Home Health Report with personalized information about in-home levels of health-relevant air pollutants and cost-sensitive recommendations on actions occupants can take to improve their home's air quality.
The investigators will (a) investigate whether and how air quality changes over time in control and intervention homes and (b) survey intervention households on the utility of the Home Health Reports.
Study Overview
Status
Recruiting
Conditions
Intervention / Treatment
Detailed Description
Study participation will involve: (i) an intake survey; (ii) random assignment to the intervention or control group (this will be done in blocks of 4 households, to maintain balance in the intervention and control groups over the course of study enrollment); (iii) three in-home air quality monitoring deployments with the Home Health Box; (iv) three Home Health Reports (for those randomly assigned to the intervention group) generated from data the Home Health Box provides; and (v) a follow-up survey in a subset of intervention households to investigate the value and utility of the Home Health Report.
The Home Health Report will provide quantitative information about health-relevant pollutants (fine particulate matter, carbon dioxide, nitrogen dioxide, and volatile organic compounds), their levels compared to health-based guidelines, their potential sources, as well as no- and low-cost actions occupants could take to improve indoor air quality.
The Home Health Report will be designed to maximize utility to residents.
Each Home Health Report will be provided within approximately three to four weeks after the corresponding Home Health Box has been received from the household.
The second Home Health Box deployment will occur within several weeks to one month of the household receiving their first Home Health Report.
The third and final Home Health Box deployment will occur within several weeks to one month of the household receiving their second Home Health.
Households in the control group will also receive three Home Health Box deployments spaced approximately four to eight weeks apart, but will not receive Home Health Reports after the first and second deployments.
At the close of their participation in the study, households in both the intervention and control groups will receive a comprehensive Home Health Report, including results from all three Home Health Box deployments and recommended actions occupants could take to improve their home air quality.
In total, participation in this study will last between four to six months.
Study Type
Interventional
Enrollment (Estimated)
250
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Ellison Carter, PhD
- Phone Number: 2192417141
- Email: ellison.carter@colostate.edu
Study Contact Backup
- Name: Hope Cruse
- Phone Number: (303) 724 - 0732
- Email: hope.cruse@cuanschutz.edu
Study Locations
-
-
Colorado
-
Aurora, Colorado, United States, 80045
- Recruiting
- UCHealth
-
Contact:
- Hope Cruse
- Phone Number: 303-724-0732
- Email: hope.cruse@cuanschutz.edu
-
Sub-Investigator:
- Fernando Holguin, MD
-
Fort Collins, Colorado, United States, 80523
- Recruiting
- Colorado State University
-
Contact:
- Ellison Carter, PhD
- Phone Number: 219-241-7141
- Email: ellison.carter@colostate.edu
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- living in home for at least next six months
Exclusion Criteria:
- if participants will not be living in the same household within six months of enrollment
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Intervention
The Home Health Report will provide quantitative information about health-relevant pollutants (fine particulate matter, carbon dioxide, nitrogen dioxide, and volatile organic compounds), their levels compared to health-based guidelines, their potential sources, as well as no- and low-cost actions occupants could take to improve indoor air quality.
The Home Health Report will be designed to maximize utility to residents.
Each Home Health Report will be provided after the corresponding Home Health Box deployment.
The second Home Health Box deployment will occur after the household receiving their first Home Health Report.
The third and final Home Health Box deployment will occur within one month of the household receiving their second Home Health Report.
|
The Home Health Report has been described in the intervention arm description.
|
No Intervention: Control
Households in the control group will also receive three Home Health deployments spaced over several months, but will not receive Home Health Reports after the first and second deployments.
At the close of their participation in the study, households in the control group will receive a comprehensive Home Health Report, including results from all three Home Health Box deployments and recommended actions occupants could take to improve their home air quality.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
In-Home Air Quality
Time Frame: from eight to up to 24 weeks
|
In-home concentrations of fine particulate matter, nitrogen dioxide, and volatile organic compounds.
|
from eight to up to 24 weeks
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Ellison Carter, PhD, Colorado State University
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
March 11, 2024
Primary Completion (Estimated)
June 30, 2025
Study Completion (Estimated)
June 30, 2025
Study Registration Dates
First Submitted
August 30, 2023
First Submitted That Met QC Criteria
September 6, 2023
First Posted (Actual)
September 11, 2023
Study Record Updates
Last Update Posted (Actual)
April 18, 2024
Last Update Submitted That Met QC Criteria
April 16, 2024
Last Verified
April 1, 2024
More Information
Terms related to this study
Other Study ID Numbers
- 23 - 0817
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
YES
IPD Plan Description
Our human subjects work will generate a comprehensive dataset that includes information on in home exposures, in-home activities, and home air quality in the form of quantitative, reference grade information on aerosol and gas constituents in indoor air.
After de-identifying these data (including location data), we will publish these data in peer-reviewed journals.
We will also generate subject response data from surveys and interviews.
These data will be organized, assembled, and analyzed for publication in peer-reviewed journals.
Standard restrictions would apply to the secondary research use of data involving human subjects, and these data would only be made available through a written agreement with the party requesting the data, after being deidentified.
IPD Sharing Time Frame
Data will become available to researchers associated with the project via the collaborating institutions as the data are being collected and for up to three years beyond the end of the study period.
IPD Sharing Access Criteria
Researchers will be eligible for access if they are members of the overall study team.
IPD Sharing Supporting Information Type
- STUDY_PROTOCOL
- SAP
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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