Pain Management in Elderly Patients With or Without Cognitive Frailty Hospitalized "ALGOGER" (ALGOGER)

Retrospective Study of Protocol-based Pain Management in Elderly Patients With or Without Cognitive Frailty Hospitalized at UPOG for Fracture of the Upper Extremity of the Femur in 2022

Today, the standard treatment is to operate on patients suffering from a fracture of the upper end of the femur. The aim of treatment is to enable immediate mobilization and weight-bearing, and as rapid a return as possible to normal living conditions.

Surgery is the best treatment option. It maximizes the chances of functional recovery and, by stabilizing the fracture, reduces pain: it is the most effective and longest-lasting analgesic.

Adequate analgesia in elderly patients with femoral neck fractures has a beneficial effect. In particular, a lower probability of death has been shown in cervical fracture patients receiving opioids than those not receiving them.

Pain management is a matter of protocol in the UPOG department of the CHU de Nîmes.

Pain prevention appears to improve morbidity and mortality. Cognitive fragility, such as neurocognitive disorders, confusion or long-term use of psychotropic drugs, appear to be confounding factors in pain management.

The investigators therefore wished to observe whether the presence of cognitive fragility has an impact on pain management on the ward, despite protocol-based management.

Study Overview

• Status: Recruiting
• Conditions: Cognitive Deterioration

• Study Type: Observational
• Enrollment (Estimated): 350

Contacts and Locations

• Study Contact: Name: GAULTIER; Phone Number: O6.05.16.89.71; Email: josephine.gaultier@free.fr
• Study Contact Backup: Name: SIMONET; Phone Number: 0466685148; Email: anne.clarisse.simonet@chu-nimes.fr

Study Locations

• France
  • CHU De Nîmes
    • Nîmes, CHU De Nîmes, France, 30029
      • Recruiting
      • GAULTIER
      • Contact: SIMONET; Phone Number: 0466685148; Email: anne.clarisse.simonet@chu-nimes.fr
      • Principal Investigator: GERONIMI-ROBELIN
      • Sub-Investigator: GAULTIER

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

All patients hospitalized at UPOG for fracture of the upper end of the femur between January 1 and December 31, 2022.

Description

Inclusion Criteria:

• Patients aged > 75 years
• Hospitalized for a fracture of the upper extremity of the femur at the UPOG of the CHU de Nîmes during 2022

Exclusion Criteria:

• Opioid allergy
• No surgical management of fracture
• Long-term treatment with high-dose opiates
• Patient has objected to the use of his or her data.

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Morphine sulfate equivalent rate in each group, mg/day	mg/day	Pre-operative
Morphine sulfate equivalent rate in each group, mg/day	mg/day	Early post-operative between Day 0 and Day 3
Morphine sulfate equivalent rate in each group, mg/day	mg/day	Late post-operative between Day 4 and day 7

Collaborators and Investigators

• Sponsor: Centre Hospitalier Universitaire de Nīmes

Study record dates

Study Major Dates

• Study Start (Actual): March 9, 2023
• Primary Completion (Estimated): October 30, 2023
• Study Completion (Estimated): October 30, 2023

Study Registration Dates

• First Submitted: June 22, 2023
• First Submitted That Met QC Criteria: September 25, 2023
• First Posted (Actual): September 28, 2023

Study Record Updates

• Last Update Posted (Actual): September 28, 2023
• Last Update Submitted That Met QC Criteria: September 25, 2023
• Last Verified: June 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pathologic Processes; Frailty
• Other Study ID Numbers: Local/2023

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No